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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Marburg Virus Prophylactic Medical Countermeasure

    SBC: Flow Pharma, Inc.            Topic: CBD18A002

    Through this STTR contract, we propose to evaluate the efficacy of our vaccine, FlowVax Marburg, in nonhuman primates (NHPs). This will be achieved through four Tasks. In Task 1, we will manufacture the vaccine in a quantity sufficient for the animal studies. In Task 2, we will perform MHC genotyping on a representative population of NHPs and, based on results, select a set of MHC-matched NHPs for ...

    STTR Phase II 2020 Department of DefenseOffice for Chemical and Biological Defense
  2. Marburg Virus Prophylactic Medical Countermeasure

    SBC: MAPP BIOPHARMACEUTICAL, INC.            Topic: CBD18A002

    There are currently no vaccines or therapeutics available for Marburg Virus Disease (MVD). Given the specter of weaponization and the terrible morbidity and high mortality rate of MVD, this represents a critical threat to the operational readiness of the Warfighter. While traditional vaccines have contributed greatly to public health, they have some limitations especially in the context of operati ...

    STTR Phase II 2020 Department of DefenseOffice for Chemical and Biological Defense
  3. Novel Circulating RNA-based Markers as Diagnostic Biomarkers of Infectious Diseases

    SBC: CFD RESEARCH CORPORATION            Topic: CBD18A001

    In resource limited settings, rapid and accurate diagnosis of infections is critical for managing potential exposures to highly virulent pathogens, whether occurring from an act of bioterrorism or a natural event. This is especially important for hard to detect intracellular bacterial and alphavirus infections, that overlap symptomatically and often treated empirically due to a lack of reliable an ...

    STTR Phase II 2020 Department of DefenseOffice for Chemical and Biological Defense
  4. Hardened, Optically-Based Temperature Characterization of Detonation Environments

    SBC: SA PHOTONICS, LLC            Topic: DTRA19B001

    Improving the effectiveness of counter-WMD operations requires improved understanding of weapon-target interaction. Specifically, time-resolved measurements of temperature and composition are required to allow temporal evolution of a detonation fireball. To address this need, SA Photonics will develop MONITOR, a laser-based temperature diagnostic that will enable wide dynamic range temperature mea ...

    STTR Phase I 2020 Department of DefenseDefense Threat Reduction Agency
  5. DOEYK: Detecting Objects with Enhanced YOLOv3 and Knowledge Graph

    SBC: Intelligent Automation, Inc.            Topic: DTRA19B002

    Current state-of-the-art object detection algorithms are almost exclusively based on Deep Convolutional Neural Network (DCNN). These algorithms all require a large amount of labeled examples for each of the object categories they can recognize. These algorithms will fail for novel objects that only very few or even no prior examples are available. These algorithms are also far less accurate when c ...

    STTR Phase I 2020 Department of DefenseDefense Threat Reduction Agency
  6. Production of Inactivated Virus Vaccines Using Supralethal Irradiation

    SBC: BIOLOGICAL MIMETICS, INC.            Topic: DTRA14B002

    We seek a proof-of-concept study for the development of a new platform technology for the rapid and complete inactivation of pathogen infectivity for vaccine development of medically important micro-organisms (e.g. viruses, bacteria and parasites). A recently discovered reconstituted Mn+2-decapeptide phosphate complex (Mn-Dp-Pi) of the radiation-resistant bacterium Deinococcus radiodurans was foun ...

    STTR Phase I 2015 Department of DefenseDefense Threat Reduction Agency
  7. A Novel, Microscale, Distributable Sensor Technology for Ionizing Radiation

    SBC: CFD RESEARCH CORPORATION            Topic: DTRA14B004

    Terrorist use of radioactive nuclear materials via nuclear and/or radiological dispersion devices (dirty bombs) is a serious threat. Therefore, it is critical to detect the proliferation of nuclear material. Critical challenges facing this objective include: (a) high sensitivity detection of signature emissions (e.g., gamma rays) from common radioactive isotopes behind shielding, and (b) cost-effe ...

    STTR Phase I 2015 Department of DefenseDefense Threat Reduction Agency
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