Award Data

The U.S. Air Force is interested in developing hypersonic vehicles including reusable transport aircraft, cruise missiles, and unmanned systems. Hypersonic flight regimes result in multifaceted and very difficult design challenges that can be encapsulated into an aerothermoelastic problem, which is a complex interaction of structural, thermal, and aerodynamic mechanisms. When a flexible structural ...

This is a prototype system that will take raw observation data, detect and characterize maneuvers, and use reinforcement learning to understand and react to evasive RSO behaviors in near real time. This will provide a framework to evaluate autonomous behavior strategies, such a safety, effectiveness, and robustness to manipulation. This work will enable surveillance operators to distinguish betwee ...

The DF&NN team has significant experience in delivering Space Domain Awareness tools. These tools will be applied to 2 years of GEO ephemeris data of active satellites at DF&NN. The RDESB prototype will reduce the risk in rapidly discovering the behavioral patterns of potentially evasive and/or ambiguous active resident space objects. RDESB will detect non-Keplerian behavior in ephemeris data for ...

Space superiority requires space protection and space situational awareness (SSA), which rely on rapid and accurate space object behavioral and operational intent discovery. The focus of this project is to develop a stochastic approach for rapid discovery of evasive satellite behaviors. Designing the innovative decision support tool has numerous challenges: (i) partial observable actions; (ii) eva ...

In response to the challenges described in AF173-CT05, Applied Defense Solutions (ADS) and the University of New Mexico (UNM) (equivalently, the ADS Team) propose to research and develop innovative validation and verification (V&V) algorithms for spacecraft GN&C. The ADS Team is unique in that it brings operational flight GN&C software experience (ADS) with cutting edge research on algorithm V&V ( ...

Abstract E cigaretteE ciguse has rapidly proliferated worldwideIt is speculated that E cig use may exceed conventional cigarette use withinyearsCigarette smoking is the leading preventable cause of death and disabilityAs E cigs are a relatively new productstudies are needed to determine their long term detrimental effectssome of which may be similar to the long term detrimental effects of nicotine ...

Measurement of cervical dilation during late pregnancy and labor informs decisions in the management of labor and deliveryPrior published research suggests that practitioners are onlytoaccurate when judging cervical simulatorsWhen measuring laboring womentwo practitionersandaposmeasurements agree onlyof the timeDrEva Martin of Elm Tree Medical Incdeveloped a novel deviceDilaCheckto enable practiti ...

Traumatic brain injuryTBIis a substantial health care issue affecting both civilian and military populationsAlthough extremes of head injury are recognizablemild to moderate TBImmTBIis more difficult to diagnose leading to a need for the identification of circulating biomarkers of brain injury that may facilitate early identificationUsing a rat model of TBI we identified a novel marker of neuronal ...

PROJECT SUMMARY Melanoma is one of the most prevalent cancers and is estimated to account for overdeaths inin the United States aloneAlthough highly curable when detected earlytheyear survival rates decline precipitously for patients with regionaland metastaticmelanoma indicating a lack of efficacy of conventional therapiesand a strong need for novel therapies for this patient populationIn respons ...

There is increasing interest in the use of biomarkers in clinical drug developmentwith much of thest Century Cures Act focused on encouraging this approachIdeallybiomarkers could provide and acute and objective read out of drug mechanism of actionpharmacodynamic biomarkersor prediction of later clinical benefit or harmsurrogate outcome measureHoweververy few biomarkers have been validated for rout ...