Award Data

Netrias, the Texas A&M Health Science Center (TAMHSC) and the Texas A&M Engineering Experiment Station (TEES), and expert consultants will expand and extend the capabilities of PathEngine, an advanced computational platform that ingests and integrates a corpus of bacterial phenotype measurements suitable for the training of a pathogenicity machine learning algorithm. We will enhance the data integ ...

Stottler Henke proposes PACT to address the threat posed by unknown/novel bacteria. Stottler Henke’s solution leverages AI/ML technologies to assess the pathogenic potential of unknown/novel bacteria for DARPA’s Biological Technologies Office. Threat assessment is inferred from phenotype as characterized by a series of assays developed by Harvard University as part of DARPA’s Friend or Foe p ...

In resource limited settings, rapid and accurate diagnosis of infections is critical for managing potential exposures to highly virulent pathogens, whether occurring from an act of bioterrorism or a natural event. This is especially important for hard to detect intracellular bacterial and alphavirus infections, that overlap symptomatically and often treated empirically due to a lack of reliable an ...

There are currently no vaccines or therapeutics available for Marburg Virus Disease (MVD). Given the specter of weaponization and the terrible morbidity and high mortality rate of MVD, this represents a critical threat to the operational readiness of the Warfighter. While traditional vaccines have contributed greatly to public health, they have some limitations especially in the context of operati ...

Through this STTR contract, we propose to evaluate the efficacy of our vaccine, FlowVax Marburg, in nonhuman primates (NHPs). This will be achieved through four Tasks. In Task 1, we will manufacture the vaccine in a quantity sufficient for the animal studies. In Task 2, we will perform MHC genotyping on a representative population of NHPs and, based on results, select a set of MHC-matched NHPs for ...

As unmanned aircraft systems (UAS) become more prevalent there is an increasing desire to automate UAS navigation and control. To enable future UASs to perform a wider variety of missions, they must be able to complete autonomous relative navigation to accomplish missions. Current technologies rely heavily on GPS measurements, which are undesirable since GPS signals may be unavailable in many DoD ...

Clearly demonstrate that a sub-sea methane harvesting power station can be developed, deployed, and operated to produce power at the 1kW level. Show that no major hurdles remain to produce a fully functional prototype system. Such a system will harvest methane from a productive methane ocean seep and operate autonomously for several years.

Software and hardware flaws can be exploited to make programs perform unintended computations or leak sensitive data. We propose to counter these threats by isolating libraries and other program units inside a single process. The developer will insert source-level annotations that i) map code and data units to compartments and ii) capture how each compartment is intended to interact with others, i ...

The Defense Advanced Research Projects Agency (DARPA) is seeking to utilize small reconfigurable robotic system to operate independently in unknown highly complex environments. We propose a modular reconfigurable robot, which presents several locomotion modality to handle different type of off-road environments. We proposed several configurations for the robot, which are well-suited to the type of ...

DoD has a critical need for protecting sensitive data to make sure that only the intended, trusted programs or parts of programs can access the data. This protection must be also effective when data is loaded into memory while being processed by software. Lately, the side-channel attacks which are based on information gained from the implementation of a computer system rather than exploiting algor ...