Award Data

Aflatoxins are a paradigm among fungal produced mycotoxins that are present in food supplies and are strongly associated with increased risk forthe development of hepatocellular carcinoma. Currently, there are no known countermeasures that can selectively mitigate aflatoxin toxicity andthe available options are only symptomatic treatments. To meet this challenge, we propose to harness the microbio ...

Surgical simulations aiming to support surgeon practices and medical education have attracted enormous research effort over the last two decades. However, the physical reality, especially on simulating aggregated tissue interaction, is still unsatisfactory. In this proposed work, an open source surgery simulation framework, SoFMIS, will be utilized and enhanced with tissue interaction models to a ...

Small drinking water systems consistently provide safe, reliable drinking water to their customers; however challenges of such systems include; lack of financial resources, aging infrastructure, lack of scale, and technical/logistical challenges associated with regulation compliance. The deployment ofnew cost-effective monitoring technologies hold opportunities to substantially advance infrastruct ...

Polyurethanes are now made by reacting two components, one of which has toxic isocyanate groups. Isocyanates are especially hazardous to workers that spray-apply polyurethane paints. Researchers have developed less hazardous ways to make polyurethane, but they have poor performance, cure too slowly or are too expensive. In this project, TDA Research, Inc. (TDA) will develop new non-isocyanate two- ...

Environmental DNA from three extreme samples will be isolated, cloned into a fosmid library (5760 clones) for sequencing. The sequencing datawill cover ~ 240 Megabases and will be assembled into contigs long enough (~ 40 Kilobases) to represent potential biosynthetic gene clusters(BGCs). This data will be compared to BGC databases looking for homology to antibiotic targets of DoD interest and with ...

Typical procedures for respirator masks sizing and protective fit test are time-consuming and user intensive, requiring taking anthropometric measurements of the wearer, sampling the wearers breathing zone and the use of specialized tools and equipment. The proposed software app aims to quickly, accurately and automatically perform respirator mask sizing and predict protective fit using only 2D im ...

The United States Department of Defense (DOD) requires a container for the safe transportation of chemically or biologically contaminated materials, in accordance with DOD, federal and international standards.These materials must be packaged in a manner so that they arrive at their destination in good condition and without presenting a hazard to nearby persons during transport.The packaging requir ...

Coupling high intensity and high flux x-ray capabilities with impact drivers (lasers, gas guns, etc.) provide opportunity for directly probing material deformation mechanisms under extreme loading conditions. Limitations in existing x-ray detection capabilities prevent complete mapping of the temporal evolution of dynamic material events under fast loading rates. X-ray energy detection > 20 keV is ...

U.S. forces require the ability to protect personnel from an attack by chemical warfare (CW) agents. TDA Research, Inc. (TDA) is currently developing novel chemistry to mitigate the effects of CW agents. In this effort TDA will extend the development of a

TDA Research, Inc., a leading developer of specialty sorbents, will design and test sorbents for incorporation into passive dosimeter badges designed by a major dosimeter manufacturing company. For the past 15 years, wearable passive major dosimeter badges provided by our partner. have been used by crews of U.S. submarines to monitor exposure to chemical hazards, including many of concern in the s ...