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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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An adjuvanted influenza vaccine platform for dose sparing, multiplexing, and rapid deployment
SBC: POP Biotechnologies Inc. Topic: NIAIDAbstract Influenza is the cause of considerable morbidity and mortality globally. Certain groups, i.e., infants, pregnant young women, and older adults are especially at risk for severe disease. Despite immunization being the most effective and economical prophylactic approach, vaccines often provide less than optimal defense against an influenza illness, with efficacies ranging from 10-60%. This ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
An Immersive Virtual Reality Peer Support Application for Individuals with Opioid Use Disorder: Development and Initial Evaluation
SBC: Very Real Help, LLC Topic: NIDAPROJECT SUMMARY Drug overdoses are the leading cause of death in the United States with approximately 72,000 people dying from drug overdose in 2017. Many of these fatalities occurred in individuals with opioid use disorder (OUD), which is one of the greatest public health issues confronting the United States today. Digital Recovery Support Services (DRSs) that include peer support, psychoeducatio ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
A Novel Approach to Purifying iPSC Derived Cell Cultures
SBC: HocusLocus Inc. Topic: 200DESCRIPTION provided by applicant We are pioneering an RNA based switch technology called structurally interacting RNAs sxRNA which utilizes post transcriptional gene regulation as a reporter for miRNA detection Normally RNA binding proteins RBP associate with a andapos stem loop structure to facilitate translation of an upstream coding region by as much as an order of magnitude It is ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
A Novel, Microscale, Distributable Sensor Technology for Ionizing Radiation
SBC: CFD RESEARCH CORPORATION Topic: DTRA14B004Terrorist use of radioactive nuclear materials via nuclear and/or radiological dispersion devices (dirty bombs) is a serious threat. Therefore, it is critical to detect the proliferation of nuclear material. Critical challenges facing this objective include: (a) high sensitivity detection of signature emissions (e.g., gamma rays) from common radioactive isotopes behind shielding, and (b) cost-effe ...
STTR Phase I 2015 Department of DefenseDefense Threat Reduction Agency -
A novel monobody-drug conjugate to treat mutant Ras multiple myeloma
SBC: TEZCAT Laboratories LLC Topic: 102Project Summary: Multiple myeloma is an incurable hematologic malignancy with an expected median survival of 7-8 years. The proteasome inhibitors, bortezomib, carfilzomib and the recently approved ixazomib, are a mainstay of current myeloma treatment. Despite an initial response rate approaching 90% to proteasome inhibitor-containing combinations, all patients relapse and eventually become resista ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
A Novel Polymeric Valve for Transcatheter Aortic Valve Replacement
SBC: POLYNOVA CARDIOVASCULAR INC Topic: NHLBIProject Summary: A Novel Polymeric Valve for Transcatheter Aortic Valve Replacement Minimally invasive transcatheter aortic valve replacement (TAVR) has emerged as an effective therapy for the unmet clinical need of inoperable patients with severe aortic stenosis (AS). Recent longitudinal follow-up studies of TAVR patients however indicate that this procedure and associated technology may result i ...
STTR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health -
A PET Diagnostic for Imaging Bacterial Infection
SBC: CHRONUS PHARMACEUTICALS, INC. Topic: NIBIBPROJECT SUMMARY Bacterial infections such as those of prosthetic joints, bones (osteomyelitis) and heart valves (infective endocarditis) are difficult to diagnose and treat, and are a major cause of mortality, morbidity and health care costs. The long-term goal of our program is to develop a positron emission tomography (PET) radiotracer that can be used for non-invasive PET imaging to detect and ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
Automated Assessment of Leptomeningeal Collaterals on CT Angiograms
SBC: KITWARE INC Topic: 108DESCRIPTION provided by applicant The primary goal of this study is to develop an automated scoring system of leptomeningeal collaterals based on CT angiography CTA as a quantitative assessment of acute stroke Leptomeningeal collaterals provide an alternate path of blood flow in the setting of a proximal occlusion The presence and effectiveness of leptomeningeal collaterals i e andquot c ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Biodegradability and Biocompatibility of a Shape Memory Polymer Wrap to Improve Saphenous Vein Graft Patency in Peripheral and Coronary Artery Bypass Grafting Surgeries
SBC: VenoStent, Inc. Topic: NHLBIPROJECT SUMMARY/ABSTRACT Peripheral artery disease (PAD) affects nearly 12 million people in the United States. One of the most common surgical therapies is peripheral artery bypass grafting (PABG). Some patients are eligible for less invasive treatment options like angioplasty, but patients with calcified lesions are not. In patients that do receive PABG, approximately 20% fail within the first y ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
Broad Spectrum Bitter Taste Antagonists Discovery
SBC: DISCOVERYBIOMED, INC. Topic: NIDCDPrincipal Investigators for Small Business: DiscoveryBioMed, Inc. (DBM) and Monell Chemical Senses Center Project Summary Abstract Bitter taste in foods and medicines presents a barrier to overcoming global public health challenges: food insecurity, poor nutritional health, and poor compliance with medication use, particularly among children and the elderly. Sugar and salt, the mainstays to addres ...
STTR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health