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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Omniphobic Cerebral Shunt to Eliminate Clogging and Dysfunction
SBC: FREEFLOW MEDICAL DEVICES LLC Topic: 106PROJECT SUMMARY Hydrocephalus causes long term neurological problems and patient suffering. Current treatments, most of which involve surgical diversion of cerebrospinal fluid (CSF) with shunt catheters, fail at an alarming rate. Approximately 98% of all shunts fail within 10 years, and this failure rate is the dominant contributor to the $2 billion-per-year cost that hydrocephalus incurs on our h ...
STTR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health -
Nucleotide inhibitors as precision medicine in breast cancer
SBC: RECOMBINATION THERAPEUTICS LLC Topic: 102Breast cancer is the most frequently diagnosed cancer in women, and 15-20% of patients have triple negative breast cancer (TNBC) which results in a 70% mortality rate within 5 years of diagnosis. 10-15% of TNBC patients possess heritable mutations in the BRCA1/BRCA2 tumor suppressor genes which promote homologous recombination (HR) of DNA double-strand breaks (DSBs). BRCA-mutated cells are highly ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
Portable Affordable Innovative and Smart Device-Coupled Electronic Fetal Monitoring System to Improve Rural Access to Obstetrics Services and Improve Outcomes in Rural Communities
SBC: Fetal Life, LLC Topic: 102Obstetricians measure fetal heartrate (FHR) and uterine contractions to evaluate fetal health during pregnancy and labor. This monitoring is performed to decrease the development of complications while minimizing the need for unnecessary obstetric interventions and is especially important for women with high-risk pregnancies. However, many women, especially in rural areas, do not have the time or ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
Catheter Based Cardiovascular Device Retrieval System
SBC: Onocor LLC Topic: NHLBIRecent advances in technology have made possible the treatment of a growing number of structural cardiovascular diseases by catheter based procedures. Atrial septal defects (ASD), ventricular septal defects (VSD), aortic aneurysm, congenital defects and valve disease are all currently being treated with catheter based strategies. These procedures are complex and are prone to device misplacement, e ...
STTR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health -
Eliminating the human factor from stereotaxic surgeries
SBC: POPNEURON LLC Topic: 104Project Summary: The main goal of this research project is to develop a new line of new stereotaxic devices for small animal research that outperforms existing devices in terms of accuracy, reproducibility, and ease of use. Advancing a tool such as an electrode, injection pipette or optical fiber through a small hole in the cranium, sometimes over long distances, and placing it precisely in a part ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
Novel AMPK Activators for the Treatment of Lithium-Induced Nephrogenic Diabetes Insipidus
SBC: NephroDI Therapeutics, Inc. Topic: 400PROJECT SUMMARYNephrogenic diabetes insipidus (NDI) is a disease characterized by the production of very large quantities of dilute urine from an inability of the kidney to respond to vasopressin. NDI can be either congenital or acquired. Acquired NDI is a common side effect of lithium therapy. Lithium-induced NDI patients produce over 3 L/d of dilute urine. Lithium is the first-line treatment for ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
Functionalized perfluorocarbon nanoemulsions for enhanced cell labeling for fluorine-19 MRI detection
SBC: CELSENSE, INC. Topic: NIBIBThis project aims to develop and commercialize a novel MRI probe technology for the cell therapy tools market. This project will transfer technology invented in the academic lab of Dr. Ahrens at UCSD, to Celsense, Inc., an established company that offers imaging agents for visualizing and quantifying the trafficking of cell therapies and inflammation in the body using magnetic resonance imaging (M ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
Real-time Multimodal Diffuse Reflectance and Polarization Imaging Based Nerve Identification in Surgical Field of View
SBC: YAYA SCIENTIFIC LLC Topic: NIBIBPROJECT SUMMARY We propose to develop a novel non-contact, label-free multimodality imager that provides real-time intraoperative identification of nerves within the surgical field-of-view to facilitate the prevention of unintended nerve damage (termed iatrogenic nerve injury) during surgical procedures, as they are a major source of postsurgical complications, e.g., chronic pain. In the United St ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
Enabling membrane protein structural analysis: Tools for capillary diffusion crystallization and remote in situ diffraction experiments
SBC: Elk Valley Enterprises, Inc. Topic: 400Project SummaryThis proposal is to develop an integrated capillary counter diffusion-based approach to in situ collection of macromolecule diffraction data. The method to be developed will enable both cryogenic and ambient temperature data collection, with the latter being critical to structure-based drug design. The approach is based on a capillary that is pre-mounted in a holder that facilitates ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
Lead compound discovery from proprietary mycobacterial strains for treatment of PTSD
SBC: MYCOBACTERIA THERAPEUTICS CORPORATION Topic: NCCIHProject Summary Immunoregulation, i.e., balanced expression of regulatory and effector T cells, is thought to be compromised in modern high-income settings due in part to reduced contact with commensal and environmentally derived bacteria, also known as “old friends”. Failed immunoregulation is thought to be one factor contributing to recent increases in stress-related and chronic inflammatory ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health