Award Data

SpringActive Inc. collaborating with Arizona State University will design and build a spring-based, passive prosthetic ankle that stores energy in the stance phase and returns it at push-off to propel the user forward. The team will leverage experience in designing tuned spring ankles. A plantarflexion spring will allow the ankle to plantarflex smoothly and align to the ground after heel strike. ...

Medical moulage is used in medical training to simulate injuries or pathologies, however current moulage is static and does not provide the trainee feedback on the quality of care or ultimate outcome of that care. Allowing a trainee to witness the injury or pathology -morph- while treatment is being provided can provide feedback on any potential mistreatment and enhance the learning and proficienc ...

This proposal aims to develop a wireless IMU (WIMU) activity recognition system for SpringActive`s powered ankle prosthesis, Odyssey. Robust activity detection via WIMU will revolutionize the state-of-the-art in powered, lower limb prosthetics by integrating (i) bio-inspired intelligence with (ii) biomimetic mechanics into a highly-maneuverable, smart, ankle-foot prosthesis system. Odyssey is the ...

There is a lack of quantitative tools to accurately map tissue viability in a rapid and quantitative manner so a surgeon can properly excise tissue prior to grafting. Spatial Frequency Domain Imaging (SFDI) is an optical method that has been shown to be a reliable method for physiology assessment - particularly for burn depth. SFDI measures of tissue structure (scattering) and function (hemoglobi ...

Cost-effective application of advanced commercial electronics technologies in DoD space systems requires early development of radiation-hardened-by-design (RHBD) techniques, and use of simulations is critical to the efficiency of this process. CFDRC has developed an integrated, mixed-mode simulation approach allowing their NanoTCAD device physics simulator to interface with commercial circuit simu ...

Estimation of the primary parameters like IC 50 in traditional dose-response modelsmay fail or lead to misleading results when the observations are non-onotonic due to drugresistance or virus mutation in various biomedical lab research. The objective of this project isto develop a novel approach to assess dose response relationship, which is applicable to generalpharmacologic, toxicologic, or othe ...

Makel Engineering, Inc. and Sandia National Laboratories propose to demonstrate an advanced multi-modal sensor system suitable for in-situ analysis of exhaled VOCs for pilots, divers and field patients. Our proposed system will combine a micro-gas chromatograph (GC) and miniature ion mobility spectrometer (IMS) for detection of trace amounts of exhaled breath VOCs with miniature solid state sensor ...

BaySpec Inc., in collaboration with Pacific Northwest National Laboratory, proposes to develop an innovative orthogonal sensor systemthat would be able to detect, identify and quantify the inorganic components of breathing mixes, (i.e., nitrogen, oxygen, carbon dioxide, argon, helium, and water vapor), as well as individual detectable VOCs within the exhaled breath in real-time. The Phase I resear ...

The goal of this STTR effort is to design a portable, multimodal, non-contact imaging system for burn depth diagnosis and tracking of wound healing. UC and Vanderbilt University will build upon our previous efforts demonstrated via porcine model studies to combine results from structural B-mode optical coherence tomography (OCT) images and functional data (pulse speckle imaging- PSI) to classify d ...

Surgical simulations aiming to support surgeon practices and medical education have attracted enormous research effort over the last two decades. However, the physical reality, especially on simulating aggregated tissue interaction, is still unsatisfactory. In this proposed work, an open source surgery simulation framework, SoFMIS, will be utilized and enhanced with tissue interaction models to a ...