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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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A biochemical companion diagnostic platform to measure kinase inhibitor pharmacodynamics in leukemia
SBC: MICROFLUIDIC INNOVATIONS, LLC Topic: 102DESCRIPTION provided by applicant Kinase inhibitors created a new paradigm in chemotherapy and are a major focus of new oncology drug development The Bcr Abl inhibitor imatinib was a breakthrough drug for chronic myelogenous leukemia with overwhelming early results however at least of patients are either intolerant resistant or experience recurrence within years and individual respo ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
A dual-polarized Doppler Radar system for fall detection in an indoor environment
SBC: MS Technologies Corporation Topic: NIADESCRIPTION provided by applicant Falls are a leading cause of injuries and deaths among older adults OAs and will be an increasing public health concern given projections of future increases in the number of OAs in the US Fall detection and or surveillance systems are needed to enhance an OAandapos s confidence and independence and to facilitate rapid post fall responses This project wil ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Advanced Data Association Algorithms to Address Emerging Threats
SBC: ARCHARITHMS INC Topic: MDA19T001The proposed approach provides innovative sensor data association algorithms capable of performing correct data association in multi-target tracking environments with one or more sensors. Current air and missile threats have the ability to fly non-ballistic, highly maneuvering hypersonic trajectories, and the ability to maintain closely spaced trajectories. Improved detection/track association is ...
STTR Phase I 2020 Department of DefenseMissile Defense Agency -
AFM based nanoscale IR Spectroscopy (AFM-IR) as a characterization platform for P
SBC: Anasys Instruments Corp. Topic: 300DESCRIPTION provided by applicant Anasys Instruments and Prof Lynne Taylor of Purdue propose to develop nanoscale chemical characterization capabilities for drug formulation research This project will build on successful Phase I research demonstrating feasibility of atomic force microscope based infrared spectroscopy AFM IR in pharmaceutical applications This Phase II research will advance ...
STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health -
A Genes-to-Molecules Platform for Expanding Natural Product Diversity
SBC: Lassogen, Inc. Topic: NCCIHProject Summary Natural products (NPs) and derivatives thereof provide a rich source of chemical matter for drug discovery and development. Over the past 30 years, NP-derived drugs have accounted for more than 35% of FDA approvals. Despite their demonstrated importance, development of new NPs has slowed over the past 15 years due to the lack of efficient methods for discovery, production, and opti ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
A high-throughput kit for detection of RNA modifications
SBC: MAVERIX BIOMICS, INC. Topic: NIDADESCRIPTION provided by applicant The broad objective of this project is to develop an integrated wet lab dry lab kit for high throughput detection of RNA modifications The final product will provide all required molecular biology reagents a set of simple and robust experimental manipulations for facile analysis of modifications and researcher friendly analytic cloud based software requi ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
A hormonal therapy for preeclampsia
SBC: ADEPTHERA, LLC Topic: NICHDDESCRIPTION provided by applicant Preeclampsia is a pregnancy specific hypertensive disorder that can lead to multi organ failure seizure and maternal death Preeclampsia is also responsible for as many as of premature births in the United States Although better neonatal care has improved the likelihood of preterm babies surviving many face increased mortality and serious long term mor ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Aminonaphthyridine compounds as potential therapeutics for lung and thyroid cancers
SBC: KINARX, INC Topic: 102Over the past three decades a growing number of cancer-driving protein kinases have been successfully targeted as reflected in the approval of 49 kinase inhibitors by the Food and Drug Administration (FDA). Recent approval of the first tyrosine kinase inhibitor (Larotrectinib) for treatment of any cancer bearing mutation in neurotrophic receptor kinase validated a novel paradigm of precision targe ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
A new generation of targeted therapeutics for the treatment of cancer
SBC: NERX BIOSCIENCES, INC. Topic: NCIDESCRIPTION provided by applicant Development of novel lung cancer therapeutics targeting the DNA damage response Abstract Lung tissue is constantly exposed to a wide variety of inhaled chemical agents While the majority of these maybe innocuous those that damage DNA have severe consequences Thus the DNA damage response DDR and DNA repair in these tissues is extremely important The vast ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
A new treatment for NSAID-associated gastrointestinal damage
SBC: Anteana Therapeutics Inc Topic: NIDDKDESCRIPTION provided by applicant Non steroidal anti inflammatory drugs NSAIDs are among the most widely consumed pharmaceuticals but their prolonged use causes gastric injury and damage to the small intestine Previous work has shown that anandamide an endogenous endocannabinoid substance produced in the gastrointestinal GI mucosa plays an important role in epithelial homeostasis and re ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health