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The Award database is continually updated throughout the year. As a result, data for FY21 is not expected to be complete until September, 2022.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Marburg Virus Prophylactic Medical Countermeasure

    SBC: MAPP BIOPHARMACEUTICAL, INC.            Topic: CBD18A002

    There are currently no vaccines or therapeutics available for Marburg Virus Disease (MVD). Given the specter of weaponization and the terriblemorbidity and high mortality rate of MVD, this represents a critical threat to the operational readiness of the Warfighter. While traditionalvaccines have proven to be a huge contribution to public health, they do have some limitations especially in the cont ...

    STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
  2. Marburg Virus Prophylactic Medical Countermeasure

    SBC: Flow Pharma, Inc.            Topic: CBD18A002

    Flow Pharma, Inc. is a biotechnology company in the San Francisco Bay Area developing fully synthetic cytotoxic T lymphocyte (CTL)stimulating peptide vaccines for Marburg virus. The FlowVax vaccine platform allows us to create dry powder formulations of biodegradablemicrospheres and TLR adjuvants incorporating class I and class II T cell epitopes. FlowVax vaccines can be designed for delivery by i ...

    STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
  3. Novel Circulating RNA-based Markers as Diagnostic Biomarkers of Infectious Diseases

    SBC: CFD Research Corporation            Topic: CBD18A001

    In resource limited settings, rapid and accurate diagnosis of infections is critical for managing potential exposures to highly virulent pathogens,whether occurring from an act of bioterrorism or a natural event. This is especially important for hard to detect intracellular bacterial andalphavirus infections, that overlap symptomatically and often treated empirically due to a lack of reliable and ...

    STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
  4. Optimizing Human-Automation Team Workload through a Non-Invasive Detection System

    SBC: Stottler Henke Associates, Inc.            Topic: ST16C003

    We propose to investigate, in collaboration with MGH Voice Center and Altec, Inc., application of surface electromyography (sEMG) to assessing cognitive workload, strain, and overload. Specifically, sEMG sensors placed on the face and neck will detect emotional/motor responses to workload strain. The proposed effort will build on the substantial sEMG experience of our partner, MGH (including resea ...

    STTR Phase II 2018 Department of DefenseDefense Advanced Research Projects Agency
  5. Assess Stability and Anti-Fragility of Dense Urban Terrains

    SBC: Cordillera Applications Group, Inc.            Topic: ST17C003

    The objective of this proposal is to examine the feasibility of defining and measuring key dimensions of an urban system to include its essential functions and networks, and whether they can be modelled in a computational framework for assessing robustness and resilience of DUTs (and their tipping points) under conditions of volatility and stress. This proposal will conduct a comprehensive review ...

    STTR Phase I 2018 Department of DefenseDefense Advanced Research Projects Agency
  6. Complex Networks for Computational Urban Resilience (CONCUR)

    SBC: Perceptronics Solutions, Inc.            Topic: ST17C003

    CONCUR develops a computational framework for assessing and characterizing urban environments stability or fragility in response to volatility and stress, identifying specific weaknesses as well as key tipping points which could lead to rapid systemic failure. CONCUR explicitly models urban environments as emergent complex systems, focusing attention on the critical triggers that could lead to rap ...

    STTR Phase I 2018 Department of DefenseDefense Advanced Research Projects Agency
  7. Infectious Disease Diagnostics and Differentiation of Viral vs. Bacterial Infections for Point ofCare Applications

    SBC: GeneCapture, Inc.            Topic: CBD15C001

    GeneCapture, Inc. is proposing to develop a rapid in vitro diagnostic prototype using our patented molecular-based CAPTURE (ConfirmActive Pathogens Through Unamplified RNA Expression) assay. Based on the results and experience gained in our Phase I STTR contractHDTRA1-16C-0061: Infectious Disease Diagnostics and Differentiation of Viral vs. Bacterial Infections for Point of Care Applications, we p ...

    STTR Phase II 2018 Department of DefenseOffice for Chemical and Biological Defense
  8. Forager

    SBC: Next Century Corporation            Topic: SB12A004

    Next Century Corporation will develop novel means to acquire data on patterns of exploration of web-based information. For the proposed effort, we will integrate fine-grained logging of activities across different search paths and develop new methods for extracting web content that provides and analyzes the broader context in which such activities take place. In addition, we will develop a robust ...

    STTR Phase II 2018 Department of DefenseDefense Advanced Research Projects Agency
  9. Ultra-Coherent Semiconductor Laser Technology

    SBC: Morton Photonics Incorporated            Topic: A14AT005

    In this STTR program, technology created in Professor John Bowers research group at the University of California at Santa Barbara (UCSB) to fabricate silicon photonics based integrated lasers, including wafer bonded III-V gain elements and ultra-low loss silicon nitride waveguides and microresonators, will be utilized to develop ultra-coherent integrated laser devices that are widely tunable. Nov ...

    STTR Phase II 2016 Department of DefenseDefense Advanced Research Projects Agency
  10. Infectious Disease Diagnostics and Differentiation of Viral vs. Bacterial Infections for Point of Care Applications

    SBC: GeneCapture, Inc.            Topic: CBD15C001

    The modern warfighter faces the constant threat of endemic infections, multi-drug resistant bacteria and Biological Warfare Agents. In order to provide accurate front-line treatment that will curtail the overuse of antibiotics, a rapid and robust molecula

    STTR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
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