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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Plasmid-seeded aligned nanofibrillar scaffold for acute muscle injury treatment

    SBC: Fibralign Corporation            Topic: DHP14009

    Based on encouraging Phase I feasibility results, we propose developing a novel gene therapy approach to promote guided vascular regeneration in treating extremities after traumatic injury. Our approach is to provide thread-like implants comprised of aligned nanofibrillar collagen scaffolds loaded with Hepatocyte Growth Factor (HGF) vectors (e.g., HGF DNA plasmid, modified mRNA) designed to enhanc ...

    SBIR Phase II 2016 Department of DefenseDefense Health Agency
  2. Game-Based Learning and Assessment Computer Applications with Direct Representations of Mathematics

    SBC: BRAINQUAKE INC            Topic: 1

    The final product will include a suite of three app-based puzzle games aligned to national math standards for number sense, algebraic thinking, and problem solving. The games will be designed for use in grade 5 and 6 classrooms where students develop and apply content expertise to solving challenges. The games will include an adaptive engine that assesses and adjusts content based on student level ...

    SBIR Phase II 2016 Department of Education
  3. Apps for Rapid Epidemiological Analysis: Disease Outbreak Command Station (AREA-DOCS)

    SBC: Perceptronics Solutions, Inc.            Topic: OSD11H17

    This proposal is for a subsequent Phase II for the SBIR project Apps for Rapid Epidemiological Surveillance (AREA).Our Phase II accomplishments focused on AREA handheld apps and their use for managing epidemiological data acquisition.Our proposed subsequent Phase II effort will increase the AREA capabilities for data stream integration and decision support by extending the system to a Disease Outb ...

    SBIR Phase II 2016 Department of DefenseDefense Health Agency
  4. Systems Biology Based Tools for Modeling Platelet Storage Lesion for Optimal Blood Transfusions

    SBC: CFD RESEARCH CORPORATION            Topic: DHP15011

    Vascular trauma is the leading cause of death in military environments and hemorrhage is the major preventable cause of mortality among trauma patients. Recent experience from Iraq and Afghanistan has demonstrated improved 24-h and 30-day survival in combat casualties requiring early massive transfusion. Unlike plasma and erythrocytes, which can be cold stored for longer time periods, platelets ca ...

    SBIR Phase II 2016 Department of DefenseDefense Health Agency
  5. Rapid Detection of Borrelia burgdorferi (Lyme disease) from Ticks

    SBC: VECTOR TEST SYSTEMS            Topic: DHP15006

    VecTOR Test Systems, Inc. will develop assay for rapid detection of the Lyme disease pathogen Borrelia burgdorferi in ticks in a field setting. In Phase I prototype assays to detect Borrelia burgdorferi were developed that met Phase I objectives. The development work will continue in Phase II in which the assay with the required sensitivity and specificity will be completed and evaluated in the la ...

    SBIR Phase II 2016 Department of DefenseDefense Health Agency
  6. Rapid Detection of Borrelia burgdorferi (Lyme disease) from Ticks

    SBC: NANOCOMPOSIX, INC.            Topic: DHP15006

    Lyme disease is the most common tick-borne disease in North America and one of the fast-growing infectious diseases in the United States.An inexpensive, portable and accurate diagnostic device for the detection of Borrelia bacteria in the deer tick will be developed.The diagnostic device will consist of an efficient extractor for disrupting the hard exoskeleton on the tick, an ultra-sensitive late ...

    SBIR Phase II 2016 Department of DefenseDefense Health Agency
  7. Methodologies and Tools for Securing Medical Device Systems in Integrated Clinical Environments (ICE)

    SBC: REAL-TIME INNOVATIONS, INC.            Topic: DHP15004

    The focus of this effort is to enable the deployment of patient-centric and context-aware networked medical systems. Securing medical device communications is a foundational requirement before the Medical Internet of Things can become a reality. Devices and applications need to be provisioned with certified credentials; they need to discover each other through a secure discovery process; and mecha ...

    SBIR Phase II 2016 Department of DefenseDefense Health Agency
  8. PHASE II: NON-TOXIC, HIGHLY-EFFECTIVE BIOINSPIRED CRYOPROTECTANTS

    SBC: X-Therma Inc.            Topic: DHP15013

    On-demand cell and tissue samples are critical for both mass trauma care and advanced personalized medical procedures and continue to grow in importance. Biological tissue banks to support these on-demand applications lack safe and effective long-term storage methods. Current cryopreservation techniques and protocols use toxic cryoprotective agents that prevent successful full viability recovery o ...

    SBIR Phase II 2016 Department of DefenseDefense Health Agency
  9. Ophthalmic Microendoscope

    SBC: HEDGEFOG RESEARCH INC.            Topic: DHP15016

    Ocular injuries have constituted approximately 13% of all casualties from Operation Enduring Freedom/Iraqi Freedom. Of 76 patients that sustained open globe injuries and underwent surgery at Walter Reed National Military Medical Center to restore vision, 38% ultimately went blind.In many cases, severely scarred corneas preclude adequately visualizing the retina and other intraocular structures to ...

    SBIR Phase II 2016 Department of DefenseDefense Health Agency
  10. Low-Cost Biological Solution for Reducing Carbon Pollution in Chemical Manufacturing

    SBC: INDUSTRIAL MICROBES INC            Topic: 14NCER1A

    Industrial Microbes is developing a green fermentation platform to replace carbon-emitting petrochemical production with newer methods that build chemicals out of methane and carbon dioxide.Chemical production is a major source of carbon pollution, responsible for 18% of direct industrialemissions. Our innovation is an engineered microbe that can consume carbon dioxide and methane and produce a ch ...

    SBIR Phase II 2016 Environmental Protection Agency
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