Award Data

Traumatic injuries account for 30% of all life years lost in the US and is the leading cause of death for people under 46 years of age. Uncontrolled bleeding or hemorrhage constitute 30-40% of trauma related deaths and are considered to be a major cause o

Defense Health Agency (DHA) is seeking a multi-functional diagnostic to determine blood coagulopathy in real time at point-of-care (POC). Blood coagulopathy, resulting in uncontrolled bleeding, is implicated in 80% of operating room deaths and 50% of trau

Terrorist use of radioactive nuclear materials via nuclear and/or radiological dispersion devices (dirty bombs) is a serious threat. Therefore, it is crucial to detect proliferation of nuclear material. Critical challenges include: (a) high sensitivity detection of signature emissions from radioactive isotopes, and (b) cost-effectiveness for deployment of sensor networks across large storage facil ...

At the completion of the research and development effort a Li-foil multi-wire proportional counter (MWPC) neutron detector with more than 625-cm2 of active area will be included in a portable radiation detection system. The system is expected to outperform the standards set by the ANSI N42.53 standards, and gamma-ray rejection ratio (GRR) of 1.0x10-8 or better. A gamma-ray spectrometer for isotope ...

There is a lack of quantitative tools to accurately map tissue viability in a rapid and quantitative manner so a surgeon can properly excise tissue prior to grafting. Spatial Frequency Domain Imaging (SFDI) is an optical method that has been shown to be a reliable method for physiology assessment - particularly for burn depth. SFDI measures of tissue structure (scattering) and function (hemoglobi ...

Cost-effective application of advanced commercial electronics technologies in DoD space systems requires early development of radiation-hardened-by-design (RHBD) techniques, and use of simulations is critical to the efficiency of this process. CFDRC has developed an integrated, mixed-mode simulation approach allowing their NanoTCAD device physics simulator to interface with commercial circuit simu ...

Makel Engineering, Inc. and Sandia National Laboratories propose to demonstrate an advanced multi-modal sensor system suitable for in-situ analysis of exhaled VOCs for pilots, divers and field patients. Our proposed system will combine a micro-gas chromatograph (GC) and miniature ion mobility spectrometer (IMS) for detection of trace amounts of exhaled breath VOCs with miniature solid state sensor ...

BaySpec Inc., in collaboration with Pacific Northwest National Laboratory, proposes to develop an innovative orthogonal sensor systemthat would be able to detect, identify and quantify the inorganic components of breathing mixes, (i.e., nitrogen, oxygen, carbon dioxide, argon, helium, and water vapor), as well as individual detectable VOCs within the exhaled breath in real-time. The Phase I resear ...

The goal of this STTR effort is to design a portable, multimodal, non-contact imaging system for burn depth diagnosis and tracking of wound healing. UC and Vanderbilt University will build upon our previous efforts demonstrated via porcine model studies to combine results from structural B-mode optical coherence tomography (OCT) images and functional data (pulse speckle imaging- PSI) to classify d ...

Terrorist use of radioactive nuclear materials via nuclear and/or radiological dispersion devices (dirty bombs) is a serious threat. Therefore, it is critical to detect the proliferation of nuclear material. Critical challenges facing this objective include: (a) high sensitivity detection of signature emissions (e.g., gamma rays) from common radioactive isotopes behind shielding, and (b) cost-effe ...