Award Data

Surgical simulations aiming to support surgeon practices and medical education have attracted enormous research effort over the last two decades. However, the physical reality, especially on simulating aggregated tissue interaction, is still unsatisfactory. In this proposed work, an open source surgery simulation framework, SoFMIS, will be utilized and enhanced with tissue interaction models to a ...

The modern warfighter faces the constant threat of endemic infections, multi-drug resistant bacteria and Biological Warfare Agents. In order to provide accurate front-line treatment that will curtail the overuse of antibiotics, a rapid and robust molecula

The ready availability of universal donor plasma to rapidly treat massively bleeding hospital trauma patients and warfighters with combat casualties is a key element of current recommendations for trauma resuscitation, yet universal AB donor plasma is rel

Establish a radiation-aware analysis capability in a commercial EDA design flow that will enable first-pass success in radiation-hardened by design (RHBD) for DoD ASICs in much the same way that existing EDA design suites ensure first pass functionality and performance success of complex ASICs destined for commercial applications. Layout-aware, calibrated single-event radiation models that captur ...

We propose to use a hybrid analog-digital electronic computer to solve partial differential equations (PDEs) arising in scientific simulations and high performance computing (HPC). The simulation of PDEs has extensive applications in commerce, research, and defense. Analog computation potentially decreases the time and energy needed to reach a solution by providing an ability to carry out iterativ ...

Future vaccine development should focus on rapid upscale production, long-term and broad protection, and sufficient global distribution to prevent and reduce the impact of many infectious diseases and potential epidemics. Agave BioSystems proposes to develop a novel whole-microorganism vaccine inactivation strategy involving high-throughput screen of extensive radio-protectant matrices and radiati ...

Terrorist use of radioactive nuclear materials via nuclear and/or radiological dispersion devices (dirty bombs) is a serious threat. Therefore, it is critical to detect the proliferation of nuclear material. Critical challenges facing this objective include: (a) high sensitivity detection of signature emissions (e.g., gamma rays) from common radioactive isotopes behind shielding, and (b) cost-effe ...

The Environmental Engineering Group (EEG), Inc. in collaboration with the Oak Ridge National Laboratory (ORNL) proposes to develop a novel magnetic and chemical microsensor for in-situ, real-time detection, and unattended use. We envision a micro-system built around a single type of micro-structure element integrating a monolithic optical system and electronics package. We will integrate into th ...

Current off-the-shelf Windows-based software/hardware data acquisition and control (DAC) systems are relatively slow, inflexible, and incapable of driving high speed, multi-channel systems. The proposed product will advance this technology through the development of an innovative, Windows-based Graphic User Interface (GUI) and required PC-resident module interfaced with a VXI chassis containing s ...

Time Domain Corporation proposes novel devices for achieving second harmonic generation in Laser Systems. The result will be a micro-size, layered, periodic, Semiconductor structure or a fiber Bragg grating that will perform several orders of magnitude better than devices in use today. Most second harmonic crystals that are currently used are of millimeter=size or greater. The simple design of ...