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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Commercialization of a Rapid Blood Test for Traumatic Brain Injury

    SBC: Fawkes Biotechnology, LLC            Topic: 100

    Traumatic brain injuryTBIis a substantial health care issue affecting both civilian and military populationsAlthough extremes of head injury are recognizablemild to moderate TBImmTBIis more difficult to diagnose leading to a need for the identification of circulating biomarkers of brain injury that may facilitate early identificationUsing a rat model of TBI we identified a novel marker of neuronal ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  2. Reopening the Central Airway With Needle-Size Tentacle Manipulators

    SBC: Virtuoso Surgical, Inc.            Topic: NHLBI

    Project Summary AbstractThe objective of this proposal is to perform proof of concept experiments on a new hand held surgical instrument that provides dexterity at the tip of a rigid bronchoscopeThis approach is less invasive than traditional open surgeryand will be safer than the current rigid bronchoscopic approachwhich lacks dexterity in port delivered instrumentsOur new system will feature nee ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Catheter Based Cardiovascular Device Retrieval System

    SBC: Onocor LLC            Topic: NHLBI

    During the past decade there has been an exponential growth in the numberscope and complexity of catheter based interventions for structural heart diseaseTranscatheter aortic valve replacementTAVRendovascular aneurysm repairEVARvena caval filters and intracardiac defect closure are all well developed and growing treatment strategiesThe recent FDA approval of left atrial appendageLAAocclusion for a ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Measuring Bladder Permeability with MRI Using a Novel Contrast Agent Formulation

    SBC: LIPELLA PHARMACEUTICALS INC.            Topic: 300

    ABSTRACT This Phase II SBIR proposal leverages the progress made in Phase I on the development of a novel contrast mixture enhanced Tweighted MRI technique as a safesensitiveand objective diagnostic test for the increased permeability in the luminal surface of the urinary bladder in Interstitial Cystitis Bladder Pain SyndromeIC BPSpatientsThe purpose of having such a test is ultimately to allow cl ...

    STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  5. Myocardial delivery of MMP inhibiting hydrogels

    SBC: Prohibix, LLC            Topic: NHLBI

    ABSTRACTOvermillion people in the United States currently suffer from heart failure caused by a myocardial infarctionMIand more thansurvivable MIs occur each yearThese troubling statistics amount to an economic burden of over $billion annuallyCurrent clinical treatments for MI include coronary stents and bypass surgeries to overcome the blocked artery and pharmacologic prescription to lessen the w ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  6. Development of Small Molecule Therapeutics Targeting Hemorrhagic Fever Viruses

    SBC: FOX CHASE CHEMICAL DIVERSITY CENTER INC.            Topic: NIAID

    The ultimate goal of this Phase I application is to develop novel small moleculebroad spectrum therapeutics against viral infections caused by filoviruses that depend on the PPxY L domain motif for virus egress and spread of infectionEbolaEBOVand MarburgMARVviruses are highly pathogenic and classified as Category Ahigh priority bioterror pathogensAs there are no commercially available therapeutic ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  7. Trigriluzole for the Treatment of Cocaine Addiction

    SBC: FOX CHASE CHEMICAL DIVERSITY CENTER INC.            Topic: NIDA

    We have discovered trigriluzoleTRLZa tripeptide prodrug improved version of the market drug riluzoleRLZThe glutamic acid lowering properties of RLZ are ideally suited for the treatment of cocaineCOCaddictionand TRLZ is a major advance in delivering riluzole in vivo as validated in multiple in vivo studies in mouseratcynomolgous monkey and humansPhase I PKsafety and tolerability clinical trialTRLZ ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  8. Graft-protective properties of LGM2605 in Lung Transplantation

    SBC: Lignamed, LLC            Topic: NHLBI

    LignaMedLLC is developing LGMa novel medical device that will be administered via an FDA approved ex vivo lung perfusion deviceEVLPto improve lung function parameters of ex vivo donor lungs in advance of transplant surgeryPer FDA device regulations LGMwill be fully flushed and cleared from the donor lung prior to transplantThe major challenge with lung transplantation is the oxidative damage that ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  9. Automated Object Contouring Methods and Software for Radiotherapy Planning

    SBC: Quantitative Radiology Solutions LLC            Topic: 102

    Abstract In 2015, 1,658,370 new cancer cases are estimated to occur in the US, where nearly two-thirds will have radiation therapy (RT). Given that there are over 2,300 RT centers in the US, and current systems for contouring organs at risk (OARs) rely mostly on manual methods, there is a strong commercial opportunity for producing a software system that can contour OARs in medical images at a hig ...

    STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  10. Dual Tack Mesh Fixation System: Creation of a Mesh Fixation System for Hernia Treatment and Prevention

    SBC: Paradigm Surgical LLC            Topic: 300

    Contact PD PIFischerJohn Dual Tack Mesh Fixation SystemCreation of a Mesh Fixation System for Hernia Treatment and PreventionIncisional herniaIHis a significant public health issue in the United StatesUSwith an estimatedcases per year and over $billion spent on hernia treatmentRecurrence rates for surgical IH repairs areand those who experience recurrence are susceptible to a vicious cycle of morb ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
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