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The Award database is continually updated throughout the year. As a result, data for FY21 is not expected to be complete until September, 2022.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Novel Circulating RNA-based Markers as Diagnostic Biomarkers of Infectious Diseases

    SBC: CFD Research Corporation            Topic: CBD18A001

    In resource limited settings, rapid and accurate diagnosis of infections is critical for managing potential exposures to highly virulent pathogens,whether occurring from an act of bioterrorism or a natural event. This is especially important for hard to detect intracellular bacterial andalphavirus infections, that overlap symptomatically and often treated empirically due to a lack of reliable and ...

    STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
  2. Marburg Virus Prophylactic Medical Countermeasure

    SBC: MAPP BIOPHARMACEUTICAL, INC.            Topic: CBD18A002

    There are currently no vaccines or therapeutics available for Marburg Virus Disease (MVD). Given the specter of weaponization and the terriblemorbidity and high mortality rate of MVD, this represents a critical threat to the operational readiness of the Warfighter. While traditionalvaccines have proven to be a huge contribution to public health, they do have some limitations especially in the cont ...

    STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
  3. Host-Targeted Antiviral Drugs Providing Rapid, Scalable, Stable, Broad-Spectrum MedicalCountermeasure Against Marburg Virus

    SBC: Evrys Bio, LLC            Topic: CBD18A002

    In a pandemic or exposure to weaponized Marburg virus the morbidity, mortality and social unrest that will ensue before vaccines orMilitary operating on foreign soil as well as to the population of the US Homeland. Practically all threat agents of biological origin (except forcertain non-proteinaceous toxins, typically produced by marine organisms and fungi) have their structure and vital function ...

    STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
  4. Marburg Virus Prophylactic Medical Countermeasure

    SBC: Flow Pharma, Inc.            Topic: CBD18A002

    Flow Pharma, Inc. is a biotechnology company in the San Francisco Bay Area developing fully synthetic cytotoxic T lymphocyte (CTL)stimulating peptide vaccines for Marburg virus. The FlowVax vaccine platform allows us to create dry powder formulations of biodegradablemicrospheres and TLR adjuvants incorporating class I and class II T cell epitopes. FlowVax vaccines can be designed for delivery by i ...

    STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
  5. Fast Parameter Identification for Personalized Pharmacokinetics

    SBC: Autonomous Healthcare Inc            Topic: DHP17B003

    Drug dosingcan bemademore precise by using pharmacokineticand pharmacodynamicmodeling. Pharmacokinetics is thestudy of the concentration of drugs in tissueasafunction of timeand doseschedule,whereas pharmacodynamics is thestudy of therelationship between drugconcentration and drugeffect. By relating doseto resultant drugconcentration (pharmacokinetics)and concentration to effect (pharmacodynamics) ...

    STTR Phase I 2018 Department of DefenseDefense Health Agency
  6. INSPIRE- In-Mask Sensors for Physiological Investigation of Respiratory Exhalation

    SBC: MAKEL ENGINEERING, INC.            Topic: DHP16C002

    Makel Engineering, Inc. and Sandia National Laboratories propose to demonstrate an advanced multi-modal sensor system for in-situ analysis of exhaled volatile organic compounds (VOCs) for pilots, divers and field patients. The In-Mask Sensors for Physiological Investigation of Respiratory Exhalation – INSPIRE combines a micro-gas chromatograph (?GC) and miniature ion mobility spectrometer (IMS) ...

    STTR Phase II 2018 Department of DefenseDefense Health Agency
  7. ECCCHO: Effective Combat Casualty Care Handoff Operations

    SBC: Tier 1 Performance Solutions, LLC            Topic: DHA17B002

    Approximately 70% of sentinel events in medical care are related to communication mishaps, and despite regular and frequent occurrence, an even higher percentage (80%) of severe medical errors are related to miscommunication during handoffs (i.e., the transferring of information, responsibility, and authority for patient care from one provider to another). The TiER1 team proposes to address challe ...

    STTR Phase I 2018 Department of DefenseDefense Health Agency
  8. Handoff Training for Combat Casualty Care (HTC3) Framework

    SBC: Perceptronics Solutions, Inc.            Topic: DHA17B001

    This proposal is to develop a Handoff Training for Combat Casualty Care (HTC3) Framework.Training is the crux of the handoff problem today. Patient handoffs are a crucial part of casualty care, both in military and civilian environments; and today handoffs are being performed in less than optimal fashion, with ineffective communications accounting for 80% of the handoff errors. Our new HTC3 Framew ...

    STTR Phase I 2018 Department of DefenseDefense Health Agency
  9. Infectious Disease Diagnostics and Differentiation of Viral vs. Bacterial Infections for Point ofCare Applications

    SBC: GENECAPTURE            Topic: CBD15C001

    GeneCapture, Inc. is proposing to develop a rapid in vitro diagnostic prototype using our patented molecular-based CAPTURE (ConfirmActive Pathogens Through Unamplified RNA Expression) assay. Based on the results and experience gained in our Phase I STTR contractHDTRA1-16C-0061: Infectious Disease Diagnostics and Differentiation of Viral vs. Bacterial Infections for Point of Care Applications, we p ...

    STTR Phase II 2018 Department of DefenseOffice for Chemical and Biological Defense
  10. High Fidelity Computational Models for Aggregated Tissue Interaction in Surgical Simulations

    SBC: CFD Research Corporation            Topic: DHP16A001

    Surgical simulations aiming to support surgeon practices and medical education have attracted enormous research effort over the last two decades. However, the physical reality, especially on simulating aggregated tissue interaction, is still unsatisfactory. In this proposed work, an open source surgery simulation framework, SoFMIS, will be utilized and enhanced with tissue interaction models to a ...

    STTR Phase I 2016 Department of DefenseDefense Health Agency
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