Award Data

Software and hardware flaws can be exploited to make programs perform unintended computations or leak sensitive data. We propose to counter these threats by isolating libraries and other program units inside a single process. The developer will insert source-level annotations that i) map code and data units to compartments and ii) capture how each compartment is intended to interact with others, i ...

Rapidly expanding Low Earth Orbit (LEO) satellite constellations force traditional ground-based tracking methods to adapt as the current ground sensor networks can no longer provide a data rich tracking environment. Accurate tracking information is continually consumed by the Government and private sector to varying degrees of accuracy throughout satellites’ mission lifecycles to provide and uti ...

Opterus Research and Development, Inc. (Opterus) and Colorado State University (CSU) have combined the best features of high strain composites (HSC), continuum robots, and tendon actuated robots to develop a new concept called Continuum Actuated Redundant Tendon (CART) Robot to enable self-reconfigurable modular robots that can perform various tasks (e.g., walking, crawling, wheeling, and grasping ...

As unmanned aircraft systems (UAS) become more prevalent there is an increasing desire to automate UAS navigation and control. To enable future UASs to perform a wider variety of missions, they must be able to complete autonomous relative navigation to accomplish missions. Current technologies rely heavily on GPS measurements, which are undesirable since GPS signals may be unavailable in many DoD ...

There are currently no vaccines or therapeutics available for Marburg Virus Disease (MVD). Given the specter of weaponization and the terrible morbidity and high mortality rate of MVD, this represents a critical threat to the operational readiness of the Warfighter. While traditional vaccines have contributed greatly to public health, they have some limitations especially in the context of operati ...

In resource limited settings, rapid and accurate diagnosis of infections is critical for managing potential exposures to highly virulent pathogens, whether occurring from an act of bioterrorism or a natural event. This is especially important for hard to detect intracellular bacterial and alphavirus infections, that overlap symptomatically and often treated empirically due to a lack of reliable an ...

Stottler Henke proposes PACT to address the threat posed by unknown/novel bacteria. Stottler Henke’s solution leverages AI/ML technologies to assess the pathogenic potential of unknown/novel bacteria for DARPA’s Biological Technologies Office. Threat assessment is inferred from phenotype as characterized by a series of assays developed by Harvard University as part of DARPA’s Friend or Foe p ...

Through this STTR contract, we propose to evaluate the efficacy of our vaccine, FlowVax Marburg, in nonhuman primates (NHPs). This will be achieved through four Tasks. In Task 1, we will manufacture the vaccine in a quantity sufficient for the animal studies. In Task 2, we will perform MHC genotyping on a representative population of NHPs and, based on results, select a set of MHC-matched NHPs for ...

Surgical simulations aiming to support surgeon practices and medical education have attracted enormous research effort over the last two decades. However, the physical reality, especially on simulating aggregated tissue interaction, is still unsatisfactory. In this proposed work, an open source surgery simulation framework, SoFMIS, will be utilized and enhanced with tissue interaction models to a ...

The modern warfighter faces the constant threat of endemic infections, multi-drug resistant bacteria and Biological Warfare Agents. In order to provide accurate front-line treatment that will curtail the overuse of antibiotics, a rapid and robust molecula