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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Training Simulation to Teach Alcohol Screening and Brief Intervention

    SBC: SIMMERSION LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Alcohol use disorders are common among primary care patients. They are also associated with serious adverse effects. Many health care professionals, however, often lack sufficient background in alcohol screening and brief intervention strategies to effectively help patients who use alcohol above recommended limits. In particular, they often lack the necessary i ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  2. Mobile Training of Skilled Support Personnel

    SBC: BANDEMAR NETWORKS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant) Skilled Service Personnel (SSP) support emergency response organizations during an emergency incident involving weapons of mass destruction and include laborers, operating engineers, carpenters, ironworkers, sanitation workers and utility workers. SSP called to an emergency incident rarely have recent detailed training on the chemical, biological, radiological, ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  3. Pre-clinical Feasibility Study of Tissue Oxygenation Imager

    SBC: Modulated Imaging Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Chronic wounds are non-healing wounds such as diabetic ulcers and pressure ulcers. Each year, 6.5 million cases occur in the U.S., costing the economy billions of dollars. Cost-effective and efficient management of chronic wounds depends on quick assessment and diagnosis of the underlying reasons for compromised healing. Ischemia is one of the main complication ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  4. Recombinant system for ultra-large scale biomanufacturing of therapeutic proteins

    SBC: SOLAZYME, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Solazyme, Inc. in collaboration with the City University of New York (CUNY) proposes to develop a novel recombinant protein expression platform by transforming the photosynthetic microalgal species Dunaliella salina. The organism's autotrophic production of nutrients from sunlight and extreme halotolerance will allow new biomanufacturing processes to overcome t ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  5. Development of Force Based Orthodontic Appliances

    SBC: OSCAR, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The proposed project will develop a series of new orthodontic appliances using a patented technology. Using the appliances, clinicians will be able to quantify and manipulate the orthodontic force systems, which are not feasible at present. The ability to control the force system is essential for the advancement of orthodontical treatment. It enables the orthod ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  6. Vaccine-enhanced DLI to prevent cancer recurrence after stem cell transplantation

    SBC: CERUS CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): Delayed reconstitution of antigen-specific immunity following allogeneic hematopoietic stem cell transplantation (HSCT) predisposes patients to opportunistic infections and tumor recurrence. To address these problems, we are developing a vaccination methodology using a non-replicating but highly immunogenic Listeria monocytogenes (Lm) vector. When an Lm vaccine ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  7. Nasal Delivery of Naltrexone for Treatment of Alcoholism

    SBC: INTRANASAL TECHNOLOGY, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Alcohol abuse, dependence, and related societal effects exert a tremendous toll on world-wide and American health and economics. Given this devastating impact, the significant lack of pharmaceutical intervention, even for those patients seeking treatment, is troubling. This phase 1 Small Business Technology Transfer Research (STTR) project will apply novel nasa ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  8. Multiplexed Ultrasensitive Mix-and-Read Tumor Marker Quantification Assays

    SBC: NESHER TECHNOLOGIES INC            Topic: N/A

    DESCRIPTION (provided by applicant): Nesher Technologies, Inc. (NTI) licensed from UCLA the IP for a revolutionary suite of ultrasensitive biodetection technologies involving alternating laser excitation (ALEX) fluorescence spectroscopy. These technologies were developed at the UCLA Single Molecule Biophysics Laboratory (headed by Prof. Shimon Weiss). NTI proposes to apply one of these technologie ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  9. Micro-Targeting Capillary Ballistic Delivery System

    SBC: Seashell Technology LLC            Topic: N/A

    Methods for the delivery of therapeutics, tracking dyes, genes and other substances into complex neural tissue, organotypic cultures and cell types are limited in their effectiveness. The biolistic process, based upon acceleration of carrier particles to sufficient velocity, has recently been shown to be a relatively effectual delivery method for neuronal systems. However, cell damage and tissue d ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  10. Plasmin-activated Prodrug Therapy for Pancreatic Cancer

    SBC: SERENDIPITY PHARMACEUTICALS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Pancreatic cancer is the fourth leading cause of cancer related deaths and the median survival time after diagnosis is only five months. The disease is generally metastatic with limited treatment options. Research is proposed to evaluate in vivo a newly designed, targeted, prodrug therapy for pancreatic cancer that should be effective against metastatic and res ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
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