Award Data

The modern warfighter faces the constant threat of endemic infections, multi-drug resistant bacteria and Biological Warfare Agents. In order to provide accurate front-line treatment that will curtail the overuse of antibiotics, a rapid and robust molecula

GeneCapture, Inc. is proposing to develop a rapid in vitro diagnostic prototype using our patented molecular-based CAPTURE (ConfirmActive Pathogens Through Unamplified RNA Expression) assay. Based on the results and experience gained in our Phase I STTR contractHDTRA1-16C-0061: Infectious Disease Diagnostics and Differentiation of Viral vs. Bacterial Infections for Point of Care Applications, we p ...

Empirical-based mathematical framework and computer algorithms, for representing human perception and cognition processes and limitations, which influence the recognition of salient information about rapidly changing events.

There are currently no vaccines or therapeutics available for Marburg Virus Disease (MVD). Given the specter of weaponization and the terriblemorbidity and high mortality rate of MVD, this represents a critical threat to the operational readiness of the Warfighter. While traditionalvaccines have proven to be a huge contribution to public health, they do have some limitations especially in the cont ...

Flow Pharma, Inc. is a biotechnology company in the San Francisco Bay Area developing fully synthetic cytotoxic T lymphocyte (CTL)stimulating peptide vaccines for Marburg virus. The FlowVax vaccine platform allows us to create dry powder formulations of biodegradablemicrospheres and TLR adjuvants incorporating class I and class II T cell epitopes. FlowVax vaccines can be designed for delivery by i ...

In resource limited settings, rapid and accurate diagnosis of infections is critical for managing potential exposures to highly virulent pathogens,whether occurring from an act of bioterrorism or a natural event. This is especially important for hard to detect intracellular bacterial andalphavirus infections, that overlap symptomatically and often treated empirically due to a lack of reliable and ...

The broader impact/commercial potential of this Small Business Technology Transfer Phase I project is to improve the recycling rates and efficiency of lithium ion (Li-ion) batteries, as well as lower the cost of cathode materials for Li-ion batteries. This research project will accomplish these goals by recovering cathode material from a broad spectrum of Li-ion battery regardless of size, shape o ...

The broader impact/commercial potential of this project lies in next generation gas turbines where the heart of the engine, the combustor and the blade, are constructed from ceramic matrix composites (CMCs). These developments will spell a new phase of air transportation beyond the current engines that rely upon nickel-base superalloys, which have reached their maximum capability. The ceramic engi ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) project will be the development of a highly accurate genotype analysis technique and the computational pipeline for assessing genetic provenance in crop plants. The commercial potential of the proposed products and services is based on the need to increase crop yield and accelerate breeding programs. The prop ...

The broader impact / commercial potential of this Small Business Technology Transfer (STTR) Phase I project is to enable electrification of remote oil & gas processes to reduce methane emissions, improve on-site safety, and provide leak-detection and monitoring capabilities. This will be achieved by developing a robust, efficient, small-scale power generator capable of converting on-site fuel to e ...