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The Award database is continually updated throughout the year. As a result, data for FY21 is not expected to be complete until September, 2022.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Commercialization of a Novel Therapeutic for Alzheimer's Disease

    SBC: CoPlex Therapeutics, LLC            Topic: NIA

    ABSTRACT Traditional mon therapeutictarget driven approaches to drug development for Alzheimer s diseaseADare becoming increasingly expensive and in many cases disappointingly unsuccessfulBased on preliminary in vitro and in vivo studies we have identified a novel small moleculemethyldimethyloxodihydrobenzo cnaphthyridinecarboxylateBNCthat significantly decreases neuroinflammation and production o ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Enabling point-of-care molecular diagnostics by developing an adaptive PCR instrument and on-demand kit reagents

    SBC: BIOVENTURES, INC            Topic: 172

    Because of its high sensitivitypolymerase chain reactionPCRis the gold standard for the diagnosis of many infectious diseasesbut generally only implemented in well equipped laboratoriesOne of the major roadblocks for expanding PCR to point of care markets is the lack of simplerobustsingle tube PCR designs which preserve its laboratory based high sensitivity and specificityIn this Fast Track STTR a ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Expressing humanized bacterial luciferase in stem cells: Moving beyond fireflyluciferase to expand the informational capacity of animal models for regenerativemedicine

    SBC: 490 BIOTECH INC            Topic: 400

    Expressing humanized bacterial luciferase in stem cellsMoving beyond firefly luciferase toexpand the informational capacity of animal models for regenerative medicine Project Summary This Small Business Technology TransferSTTRPhase II project proposes to develop complementary autonomously bioluminescentautobioluminescentin vitro stem cell lines and in vivo small animal model systems that enable th ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  4. RF-IR Data Fusion

    SBC: Decibel Research, Inc.            Topic: MDA12T002

    deciBel Research, Inc. and the Electrical Engineering Department at the University of Mississippi - the deciBel Team - proposes to continue to develop and mature threat physics based classification, track association/track correlation, and dynamic attributes determination threat characterization algorithms that effectively and efficiently fuse data from multiple sensors. The classification algorit ...

    STTR Phase II 2017 Department of DefenseMissile Defense Agency
  5. veriScan

    SBC: Sentar, Inc.            Topic: OSD06SP2

    The goal of the Information Assurance Run-time Auditing (IARA) Phase I project was to provide a framework that promotes the specification of software system monitoring, audit, analysis, and threat mitigation capabilities in large scale software intensive systems (LSSIS). IARA was designed to promote software assurance by incorporating novel tools that help certify the operations of untrusted soft ...

    STTR Phase II 2017 Department of DefenseMissile Defense Agency
  6. System of Systems Control Interactions

    SBC: GTD Unlimited LLC            Topic: MDA15T002

    In this research effort, the GTD team will design tools for efficiently specifying, representing, and analyzing the interactions between control systems in System of Systems (SoS). Three approaches will be considered and integrated. The first two are based in the rigorous application of H_8 control theory to the SoS design problem. The third will use complexity measures to generate a metric that c ...

    STTR Phase II 2017 Department of DefenseMissile Defense Agency
  7. Advanced Hit Detection Systems

    SBC: FREENT TECHNOLOGIES, INC.            Topic: MDA13015

    FreEnt Technologies, Inc. (FreEnt) and Johns Hopkins Universitys Applied Physics Laboratory (APL) are proposing a multiple-hit detection sensor called the Optical Lethality Measurement System (OLMS). This system is based on the Planar Optical Penetration Sensor (POPS) technology (originally developed and patented by APL) and prior art associated with the Blast Initiation Detector (BID). The BID is ...

    STTR Phase II 2017 Department of DefenseMissile Defense Agency
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