Award Data

New pathogens, both naturally occurring and adversary-engineered, are increasingly likely to emerge and represent a significant and growing risk to global health and security. These new threats often have limited genetic similarity to prior known pathogens and cannot be identified through standard genetic tests. The application of machine learning algorithms to phenotypic tests to predict pathogen ...

The US Navy, industry and the scientific community is using and developing a variety of AUVs, underwater sensors, and other systems that can be easily deployed and operated with minimal maintenance or recurring costs. A primary hindrance to the long-term implementation of these systems is the availability of in situ energy. The concepts presented herein focus on the harvesting of methane from seep ...

Autonomous underwater vehicles (AUVs) are critical to DoD undersea missions including the future capabilities for sea and sub-sea forces communication and connectivity. AUV mission lengths are currently limited to 24 hours due to the prohibitive battery storage and AUV energy demands. Makai Ocean Engineering, with the University of Hawaii’s Hawaii Natural Energy Institute (HNEI), proposes to dev ...

In this program, Morton Photonics (MP) and its STTR partner Professor John Bowers and his research group at the University of California at Santa Barbara (UCSB) will develop two truly disruptive integrated laser devices: (1) A broadly tunable integrated laser with ultra-low linewidth, ultra-low relative intensity noise (RIN), and high output power; the Integrated Coherent Tunable Laser (ICTL), whi ...

In resource limited settings, rapid and accurate diagnosis of infections is critical for managing potential exposures to highly virulent pathogens,whether occurring from an act of bioterrorism or a natural event. This is especially important for hard to detect intracellular bacterial andalphavirus infections, that overlap symptomatically and often treated empirically due to a lack of reliable and ...

The goal of this workis to establish a radiation-aware capability in a commercial EDA design flow that will enable first-pass success in radiation resiliency for DoD ASIC designs in much the same way that existing EDA design suites ensure first pass functionality and performance success of complex ASICs destined for commercial applications.Such an integrated capability does not presently exist.The ...

Next Century Corporation will develop novel means to acquire data on patterns of exploration of web-based information. For the proposed effort, we will integrate fine-grained logging of activities across different search paths and develop new methods for extracting web content that provides and analyzes the broader context in which such activities take place. In addition, we will develop a robust ...

GeneCapture, Inc. is proposing to develop a rapid in vitro diagnostic prototype using our patented molecular-based CAPTURE (ConfirmActive Pathogens Through Unamplified RNA Expression) assay. Based on the results and experience gained in our Phase I STTR contractHDTRA1-16C-0061: Infectious Disease Diagnostics and Differentiation of Viral vs. Bacterial Infections for Point of Care Applications, we p ...

Hypersonic vehicles impose demanding thermal structural requirements on refractory C/C and CMC materials. The thermal and mechanical properties from small, standard test samples on which the design of specific hypersonic hot structure components are typically based are usually not duplicated in real flight structures. Manufacturing limitations in fabricating real structures versus thin, simple sh ...

At the completion of the research and development effort a Li-foil multi-wire proportional counter (MWPC) neutron detector with more than 625-cm2 of active area will be included in a portable radiation detection system. The system is expected to outperform the standards set by the ANSI N42.53 standards, and gamma-ray rejection ratio (GRR) of 1.0x10-8 or better. A gamma-ray spectrometer for isotope ...