Award Data

Through this STTR contract, we propose to evaluate the efficacy of our vaccine, FlowVax Marburg, in nonhuman primates (NHPs). This will be achieved through four Tasks. In Task 1, we will manufacture the vaccine in a quantity sufficient for the animal studies. In Task 2, we will perform MHC genotyping on a representative population of NHPs and, based on results, select a set of MHC-matched NHPs for ...

There are currently no vaccines or therapeutics available for Marburg Virus Disease (MVD). Given the specter of weaponization and the terrible morbidity and high mortality rate of MVD, this represents a critical threat to the operational readiness of the Warfighter. While traditional vaccines have contributed greatly to public health, they have some limitations especially in the context of operati ...

Traditional spherical optics implemented on a common optical axis are the foundation of today’s fielded gunsights for small arms fire control. SA Photonics has helped pioneer the application of precision injection molded freeform optical surfaces in head/helmet mounted display (HMD) systems for augmented reality (AR), virtual reality (VR) and low light level sensor applications. SA Photonics tea ...

Military platforms and personnel rely on Global Positioning System (GPS) for precision navigation and targeting, to enhance situational awareness, improve command and mission effectiveness, and to operate more safely. However, Global Navigation Satellite System (GNSS – including GPS and other similar systems such as Galileo, GLONASS) rely on very low-powered signals susceptible to threats from j ...

High-average current and high-brightness electron beams are needed in advance applications such as ultra-high power Free-Electron Lasers (FELs) and electron accelerators. The technologically important material properties of diamond are of significant interest for development of electron emission, detector, and wide-bandgap semiconductor applications, including radiation-hard devices. A diamond amp ...

Advances in DNA sequencing technology have generated a rapid expansion of human genome information and the revelation of extraordinary individual-level genetic variation. Individual genome sequencing will soon be routine and cost-effective. To exploit this resource to the benefit of warfighters, we propose an approach for identifying and characterizing genetic variants that compromise metabolic ef ...

Melanin-based biomaterials present novel solutions to radiation shielding/countermeasures, camouflage, and insulation, among others. A scalable and sustainable production process for natural melanins is needed to support the R&D and commercialization of melanin-based technologies. MelaTech proposes to develop a fermentation system that involves a novel, rapid melanin isolation process to yield gra ...

Next-level improvements in thermal extremity protection for the current Extended Cold Weather Clothing System (ECWCS) are needed for soldiers in order to improve mobility and achieve peak performance in bitterly cold Arctic climes. In this STTR program, 2W iTech LLC proposes to develop phase change material (PCM) based thermal regulating films, in collaboration with the Multiscale Thermal Science ...

Next Generation Combat Vehicles are demanding increase power and energy density to advance current offensive and defensive weaponry (Direct Energy Weapons and Active Protection Systems. While lithium ion batteries are improving energy capacity and power supplies, there is an increase safety risk due to thermal runaway which can cause electrolyte combustion or even explosion. Energy Storage Systems ...

The ALE-PNNL Team is developing a nonflammable high capacity and high power 18650 cell using nonflammable electrolyte for military electric vehicle and energy storage applications. The 18650 cells will be nonflammable even under extreme temperature conditions and after metal penetration, even including bullet penetration.