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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Enhancing Clergy Suicide Prevention and Referral

    SBC: ACADEMIC EDGE, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Suicide is the 2nd leading cause of death in persons aged 25-34, the 3rd leading cause of death among people in the age groups 10-14 and 15-24, and the 8th leading cause of male deaths. Faith leaders and clergy have been identified in national strategic public health documents as important front-line gatekeepers for suicide prevention. Preliminary research by t ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  2. Identification of Anti-HIV Lead Compounds Targeting Rev

    SBC: ADVANCED GENETIC SYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): There is a significant need for novel HIV therapies given the emergence of viruses resistant to existing drug regimens. The Rev-RRE protein-RNA interaction in HIV plays an essential role in the transport of viral mRNA from the nucleus to the cytoplasm where it can be translated or packaged. In preliminary work, two distinct assays targeting the HIV Rev protein ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  3. CODA Assembly of Mutant Genes

    SBC: VERDEZYNE, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The general goal of this proposal is to assemble directed mutant gene sets quickly, cheaply, easily, and reliably. Mutant gene sets can share sub-assemblies, yielding savings of time, cost, and effort not possible if designed and assembled all as single genes. The approach is to build upon experience gained in Phase I, to extend and generalize methods of DNA de ...

    STTR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  4. A Pb-212 Generator Using Resistant Substrate and Rn Cold Trapping

    SBC: ALPHAMED, INC            Topic: N/A

    DESCRIPTION (provided by applicant): Targeted Pb-212 therapy in preclinical animal tests has shown a cure in groups receiving the highest dose of this therapy. Scaling the dose that was most efficacious in animal studies to people would bring the human dose required from 50 to 100 mCi. This application will research an approach that would provide a generator system that would support these require ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  5. Optimization of dipeptide-linked benzimidazole topoisomerase 1 poisons

    SBC: Apogee Biotechnology Corporation            Topic: N/A

    DESCRIPTION (provided by applicant): Derivatives of camptothecin (CPT) that inhibit Topoisomerase I (Top1) activity have demonstrated clinical utility in the treatment of various cancers. However, limitations in CPT pharmaceutical properties have driven the search for new CPT-like poisons that target the Top1 protein-DNA cleavage complex. We hypothesized that bifunctional agents that simultaneousl ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  6. Improvement of Liver Transplantation by a Sphingosine Kinase Inhibitor

    SBC: Apogee Biotechnology Corporation            Topic: N/A

    DESCRIPTION (provided by applicant): Severe shortages of donor organs limit the use of orthotopic liver transplantation (LT), the only proven therapy for end-stage liver diseases. Primary non-function (PNF) of liver grafts after transplantation typically results in recipient death or necessitates retransplantation, which further exacerbates the shortage of donor livers. Unfortunately, effective th ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  7. Tribosupplementation of Injured Joints

    SBC: TRIBOLOGICS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Injury is a well established risk factor in the pathogenesis of osteoarthritis (OA) as supported by several large longitudinal population studies. Patients with meniscal and ACL injuries in particular are at risk for early OA. Chondroprotection of the joint surface is mediated by lubricin which forms an ordered nanofilm and provides anti-adhesion via steric rep ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  8. Second Manhood: A Multimedia Intervention for Male Sexual Problems after Cancer

    SBC: Digital Science Technologies LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Sexual dysfunction is one of the most prevalent and persistent problems after cancer treatment. This Fast Track STTR will create and evaluate a multimedia educational and counseling tool to promote recovery of sexual satisfaction in men treated for cancer. Second Manhood: Recovering Your Sex Life after Cancer will be viewable over the internet, on a CD or DVD, ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  9. Exosomal microRNA profiles as diagnostic biomarkers of ovarian cancer

    SBC: TEKSHIFA, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Detection of ovarian cancer at Stage I results in 5-year survivals of greater than 90%; however, only 23% of ovarian cancers are diagnosed early, with 67% being diagnosed with metastatic disease. Thus, new markers are being sought to accurate identify patients with ovarian cancer, particularly in early stage. Emerging evidence suggests the potential involvement ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  10. An Acoustic Mobility Aid for the Visually Impaired

    SBC: BIOMIMETIC SYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this project is to develop a sonar system that can be used as a mobility aid by the visually impaired. The system will consist of an ultrasonic acoustic source using a waveform that is designed to optimize target discrimination and a pair of miniature microphones that are mounted near the ears to create natural interaural level and timing difference ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
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