Award Data

Electron spin resonance (ESR) spectroscopy is a widely used forensic technique to study post-nuclear debris fields, radiation-induced damage in solids and many other phenomena surrounding the interaction of radioactivity with solid matter. ESR spectroscopy is also used to analyze dust, smoke and other gaseous samples. Our Micro-ESR technology has the benefit of being an extremely robust, lightweig ...

The objective of the proposed Phase II project is to develop a hand-held, rapid plasmonic biosensor -- a detector based upon surfaceplasmon resonances (SPR) that incorporates a new class of supercharged proteins that functionalize a low-cost, disposable plasmonicchip. Each protein is designed to bind to a pre-determined toxin with high specificity. Upon successful binding, the protein superfoldsre ...

To address the Chemical and Biological Defense programs (CBDs) need for medical countermeasures against mycotoxin intoxication, PhysicalOptics Corporation (POC) proposes to develop a new Mycotoxin Neutralization Treatment (MyNT). This proposed solution is based on neutralizingmycotoxin from its deleterious effects by acting on multiple levels of mycotoxin metabolism through the novel combination o ...

In this proposal, we aim to validate the human gut microbiome and arid soil as a source of antibiotic natural products (NPs ) by using ametagenomic NP discovery platform developed at Radiant Genomics. Recent studies suggest that the genomes of uncultivated microorganisms,like their cultivated counterparts, encode an enormous number of NPs. Gaining systematic access to NPs using standard, cultivati ...

To address CBDs need for development of analytical approaches to fuse sensor data from multiple modalities to provide common operationalpictures in threat environments, Physical Optics Corporation (POC) proposes to develop a Wavelet-based Approach for Signal Processing andAnalysis (WASP). WASP is based on novel application of wavelet-based analysis to multimodel, multidimensional data available fr ...

As a foundational component of a Layered Sensing architecture, Toyon proposes to develop a Multi-Modal Fusion Module (M2FM) capable ofconfirming detections from Chemical, Biological and Radiological (CBR) sensing networks by fusing together information from other (non-CBR)sensors. The module will provide information to assist operators in confirming an initial CBR detection or rejecting it as a fa ...

This program develops innovative technology for chip-to-chip and intra-chip interconnects that will operate in extreme radiation environments.There is considerable development in chip-to-chip and intra-chip interconnects in the commercial market.This program will leverage these advancements and demonstrate their applicability to satellite and unmanned avionic vehicles (UAV) platforms.

The capabilities of modern x-ray light sources have opened up new areas in the study of the temporal evolution of complex materials under dynamic loading, which require detectors with high sensitivity, wide dynamic range at frame rates approaching the bunch repetition rates of modern light sources and detection at x-ray energies above 20keV.However, the capability to do such research is limited by ...

The fundamental problem addressed by this SBIR proposal is the capability to uncover new entity types, relations and topics that are implicit in text documents.Joint inference offers an opportunity to make discoveries that are more accurate and more nuanced than traditional pipelined approaches, but the hypothesis space is more complex and extraordinarily large.In this project we propose to develo ...

To address the DTRA need to enhance island-mode tactics for defense critical infrastructure (DCI) in the event of commercial power grid loss disruption due to an electromagnetic pulse (EMP) or high power microwaves (HPMs), Physical Optics Corporation (POC) proposes to develop an Optimizing power Availability and Sustainability in Islanded Sites (OASIS) strategy based on islanded power management, ...