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The Award database is continually updated throughout the year. As a result, data for FY22 is not expected to be complete until September, 2023.
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Novel Circulating RNA-based Markers as Diagnostic Biomarkers of Infectious DiseasesSBC: CFD RESEARCH CORPORATION Topic: CBD18A001
In resource limited settings, rapid and accurate diagnosis of infections is critical for managing potential exposures to highly virulent pathogens, whether occurring from an act of bioterrorism or a natural event. This is especially important for hard to detect intracellular bacterial and alphavirus infections, that overlap symptomatically and often treated empirically due to a lack of reliable an ...STTR Phase II 2020 Department of DefenseOffice for Chemical and Biological Defense
Marburg Virus Prophylactic Medical CountermeasureSBC: MAPP BIOPHARMACEUTICAL, INC. Topic: CBD18A002
There are currently no vaccines or therapeutics available for Marburg Virus Disease (MVD). Given the specter of weaponization and the terrible morbidity and high mortality rate of MVD, this represents a critical threat to the operational readiness of the Warfighter. While traditional vaccines have contributed greatly to public health, they have some limitations especially in the context of operati ...STTR Phase II 2020 Department of DefenseOffice for Chemical and Biological Defense
Marburg Virus Prophylactic Medical CountermeasureSBC: Flow Pharma, Inc. Topic: CBD18A002
Through this STTR contract, we propose to evaluate the efficacy of our vaccine, FlowVax Marburg, in nonhuman primates (NHPs). This will be achieved through four Tasks. In Task 1, we will manufacture the vaccine in a quantity sufficient for the animal studies. In Task 2, we will perform MHC genotyping on a representative population of NHPs and, based on results, select a set of MHC-matched NHPs for ...STTR Phase II 2020 Department of DefenseOffice for Chemical and Biological Defense
Information SalienceSBC: DISCERNING TECHNOLOGIES, LLC Topic: OSD11TD1
Empirical-based mathematical framework and computer algorithms, for representing human perception and cognition processes and limitations, which influence the recognition of salient information about rapidly changing events.STTR Phase II 2015 Department of DefenseOffice of the Secretary of Defense
Infectious Disease Diagnostics and Differentiation of Viral vs. Bacterial Infections for Point of Care ApplicationsSBC: GeneCapture, Inc. Topic: CBD15C001
The modern warfighter faces the constant threat of endemic infections, multi-drug resistant bacteria and Biological Warfare Agents. In order to provide accurate front-line treatment that will curtail the overuse of antibiotics, a rapid and robust moleculaSTTR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
Technologies for Rare Earths Enrichment of a Novel Low-Cost Raw MaterialSBC: Physical Sciences Inc. Topic: OSD12T01
A critical step in the extraction of elements from ore, especially rare earth elements that are found in complex minerals, is separation. Froth flotation is a highly versatile method for physically separating particles based on differences in the ability of air bubbles to selectively adhere to specific mineral surfaces in a mineral/water slurry. The particles with attached air bubbles are then ca ...STTR Phase II 2015 Department of DefenseOffice of the Secretary of Defense