Award Data

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project may reach millions of people and provide a key tool in safeguarding the public health through the COVID-19 pandemic. Sensitive, selective and quantitative detection usually requires complex laboratory-based methods and instrumentation to achieve consistent results; however, this project advanc ...

This Small Business Technology Transfer (STTR) Phase I project supports the development of a medical device that enables minimally invasive graft-based reconstruction of the urethra as a long-lasting treatment for male urethral stricture, a class of conditions causing restrictions in flow. Approximately 1% of men on Medicare are treated for stricture annually, and an estimated 1 in 5 men will get ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) project is to develop a photocatalytic process to facilitate enhanced speed and efficiency for production of key intermediate chemicals for production of Remdesivir, a potential life-saving drug in the fight against COVID-19. Remdesivir has been identified as one of the most promising treatments for COVID-19; ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project is to improve job-site safety of dry-stacking installation of masonry walls without binding mortar through the use of novel Aerated Interlocking Masonry Units (AIMU). The AIMU multi-component wall system combines the advantages of wood and those of concrete and is potentially applicable for mi ...

The broader/commercial impact of this SBIR Phase I project leverages recent advances in additive manufacturing to solve key technical hurdles and design deficits of current industry standard microcapillary needles. Microinjection is a well-established engineering technique and widely used in research and medical applications such as drug discovery and development, fertility treatments, and genetic ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) project will address concerns about the shortage of materials for Lithium-ion batteries as the number of electric vehicles increases. Lithium Sulfur (Li-S) batteries offer an opportunity because sulfur is more readily available, lower cost, and environmentally friendly. Unlike lead-acid batteries, Li-S batter ...

The broader/commercial impact of this SBIR Phase I project is to start validating a novel high-intensity focused ultrasound (HIFU) device for minimally invasive treatment of brain tumors. The current standard of care is a highly invasive cranial flap resection, which not only risks infection, uncontrolled bleeding, and damage to healthy tissue, but also has prolonged post-operative recovery. Altho ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase II project, in which a non-invasive respiratory muscle stimulation device and approach to weaning patients from mechanical ventilation will be developed, is a reduction in public health care expenditure and a reduction in morbidity for the half a million patients who have difficulty weaning from mechani ...

This STTR Phase I project addresses the problem of embedded energy in the manufacture of magnesium metal for use in vehicle light-weighting. Improving fuel economy by incorporation of light metals, especially magnesium, does not save on total lifecycle energy consumed if the magnesium was produced using conventional methods. The most energy efficient production method known is a process technology ...

The broader impacts of this Small Business Technology Transfer Phase I project relate to the increased viability of indigo as an agricultural crop competing with synthetically manufactured indigo dye. Indigo was among the major global cash crops of the 18th and 19th centuries and accounted for 100% of the indigo dye consumed in the world. Since the beginning of the 20th century, nearly 100% of the ...