Award Data

Assays for accurate diagnosis of early stages of infection with biothreat agents, on the day of infection or within a few days of infection, will find wide use in both civilian and military applications These diagnostic assays, which are anticipated to be highly specific and sensitive, will add to the repertoire of tools of hospitals and clinics that serve our armed forces personnel deployed on th ...

The Phase II strategy proposed provides for the development and optimization of a feasible, rapidly scalable, single-use manufacturing platform for the production of a mAb directed against Marburgvirus. Application of BioFactura’s StableFast patented manufacturing platform will result in an economically-produced mAb therapeutic with consistent, targeted properties for safety and efficacy. Charac ...

This project will fully develop NEWTON-AR, an augmented reality (AR) application-based engineering, computer science, and STEM puzzle game for children in kindergarten to grade three. Intended for use in classrooms, after-school programs, and at home, NEWTON-AR will combine AR, engineering, simulation, making, and programming into a sandbox game where students create, modify, simulate, prototype, ...

Check-in Check-out (CICO) is a widely used behavioral intervention for elementary and middle schools centered on goals, feedback, and communication with parents about daily behavioral performance. This project will develop a prototype platform to streamline and automate the delivery of CICO. The prototype will include an app, a user-friendly interface, and a dashboard to track progress and capture ...

In a previous National Science Foundation SBIR project, the developer created an online platform that uses songs to support mathematical learning. In the current project, the team will develop a prototype of a component of a platform to guide students in creating and producing their own music videos about algebra. The prototype will include a video production application, features to enhance learn ...

There is a tremendous need for an all-purpose paint stripper that is safe to handle and that does not harm the environment. The most popular all-purpose paint strippers are based on methylene chloride (MeCl), which is dangerous to workers and harmful to the environment. In particular, it is highly volatile, and if it is used in an area with poor ventilation it is an immediate health hazard. In ext ...

Because C&D materials constitute a significant waste stream, increasing the diversion of C&D materials, through recycling and reuse, is identified as an area of need in EPA’s Sustainable Materials Management (SMM) Program Strategic Plan. Due to a lack of technologies to quickly identify harmful constituents, C&D-materials recyclers often dispose of potentially usable materials as a matter of pre ...

Antibiotic resistant bacteria have become a major concern in discharges from hospitals, wastewater treatment plants, and agricultural runoff. A quick, inexpensive, field- deployable method of detecting antibiotic resistant bacteria in these waters is desirable. Antibiotic resistant bacteria of concern include Salmonella, Staphylococci, E. coli, Enterococci, and coliform bacteria, among others. A p ...

Harmful algal blooms (HABs) occur when the population of cyanobacteria in fresh or salt water explodes. HABs cause $14B in damages every year world-wide, because cyanobacteria release toxins into the water that threaten humans, livestock and native aquatic life. The only way to mitigate the damage from HABs is to detect them early and treat them with algicides as soon as possible. The problem is t ...

This Small Business Innovation Research project addresses the development of novel low-cost multiparameter sensors that use a new lab-on-a-chip technology platform for enabling real-time, on-line and maintenance-free deployments within water distribution systems as well as most water collection systems (i.e., storm water, grey water, etc.). At the present time, increasingly stringent local, state, ...