Award Data

DESCRIPTION provided by applicant Genomic instability is a hallmark of cancer and represents a targetable vulnerability yet is underdeveloped as a therapeutic area The central goal of this Phase program is to complete the early preclinical development of a new class of new cancer therapeutics that uniquely target RAD delivering effective cancer cell selective therapy in subsets of bioma ...

DESCRIPTION provided by applicant There is growing awareness that weakness of muscle is a significant biomedical health issue associated with many different chronic diseases and aging There are a variety of different diseases that affect muscle including muscular dystrophy fibromyalgia cerebral palsy amyotrophic lateral sclerosis and myasthenia gravis each of which carries its own uniqu ...

DESCRIPTION provided by applicant Atopic dermatitis AD or severe eczema is a very common life long skin disease with of adults in the US requiring systemic therapy Clinical manifestations of AD include multiple inflamed lesions erosions accompanied by lichenification thick leathery skin fibrotic papules and severely dry skin with increased susceptibility to infection A major uncont ...

DESCRIPTION provided by applicant The objective of this Phase II STTR grant application is to continue the R Randamp D efforts initiated in Phase I The long term objective for Arrhythmotech is to develop and market an instrument for the simultaneous recording of sympathetic nerve activity SNA and electrocardiogram ECG using electrodes on the skin This method neuECG was discovered in Dr ...

PROJECT SUMMARY ABSTRACT Interactions between the gut microbiome and the immune system have been linked to inflammatory bowel disease IBD IBD is a chronic and progressive gastrointestinal disease characterized by uncontrolled activation of the intestinal immune system resulting in severe medical complications affecting over million patients in the United States It is a disease of high u ...

DESCRIPTION provided by applicant Surface electromyogram sEMG controlled powered hand wrist prostheses are used by upper limb amputees to return partial upper limb function Conventional transradial prostheses can use surface EMG amplitudes from the residual forearm flexors and extensors to control hand closing and opening respectively Additional degrees of freedom DoFs e g wrist rota ...

The U.S. Navy is seeking new technologies and platforms to advance airborne anti-submarine warfare (ASW) and related maritime surveillance. Current magnetic anomaly detection (MAD) sensors, such as the latest versions of atomic magnetometers, are capable of very low noise operation. However, the performance of these sensors can be limited by the geomagnetic noise environment more so than by eithe ...

Agiltron in collaboration with National Renewable Energy Laboratory (NREL) will develop a new class of high-efficiency and lightweight broadband inverted metamorphic multi-junction (IMM) solar cells for the uninterrupted flight missions of unmanned aerial vehicles (UAVs). The approach is closely coupled with Agiltrons extensive experience in high-transmittance broadband and wide-angle anti-reflect ...

The Navy faces a significant challenge to its dominance of sea and air given the Anti-Access Area-Denial (A2AD) capabilities of major powers. The Navy's response, in part, is to implement technical capabilities that enable platforms to coordinate in new ways to execute offensive and defensive actions at very long range. While the Navy finalizes this Naval Integrated Fire Control-Counter Air (NIFC- ...

SI2 Technologies, Inc. (SI2) proposes to accelerate development of printed, high-efficiency phased arrays operating at Navy-relevant frequencies. The proposed development effort will include optimization of the array printing techniques from Phase I to meet the Navys phased array performance goals. The printed arrays will incorporate both printed radiating elements and an innovative printed packag ...