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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Developing Drug-like Small Molecules that Target Toxic Repeat RNAs to Alleviate Myotonic Dystrophy Type 1-derived Mis-Splicing

    SBC: Nymirum, Inc.            Topic: 104

    Project Summary Abstract Nymirum will utilize its technology platform to identify and optimize a drug-like, orally available small molecule that binds toxic CUG repeat RNAs to rescue myotonic dystrophy type 1 (DM1) derived mis-splicing and treat the disease. DM1 is a rare genetic disorder that leads to progressive muscle degeneration, cardiovascular disease, severe cognitive disabilities, insulin ...

    SBIR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  2. Portable Affordable Innovative and Smart Device-Coupled Electronic Fetal Monitoring System to Improve Rural Access to Obstetrics Services and Improve Outcomes in Rural Communities

    SBC: Fetal Life, LLC            Topic: 102

    Obstetricians measure fetal heartrate (FHR) and uterine contractions to evaluate fetal health during pregnancy and labor. This monitoring is performed to decrease the development of complications while minimizing the need for unnecessary obstetric interventions and is especially important for women with high-risk pregnancies. However, many women, especially in rural areas, do not have the time or ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  3. Rapid and non-invasive device for drug detection through sweat

    SBC: ARBORSENSE INC            Topic: NIDA

    Project Summary In the NIDA SBIR Phase I project, Arborsense will develop a portable sweat-based screening device for rapid, non-invasive, point-of-need, and quantitative detection of drugs of abuse. The use and abuse of potentially- addictive substances has become a national crisis with immense social (~93,000 deaths in 2020) and economic costs (~$400B annually). Consequently, regular drug-use te ...

    SBIR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  4. Advanced three-dimensional microscale electrode array for high-density volumetric neural interfacing

    SBC: Neuronexus Technologies, Inc.            Topic: 104

    Project Summary/AbstractSystems neuroscience is powered by progressively more sophisticated microscale neural probe technologies. Decoding the complex neural circuits underlying memory, behavior and perception often requires, in part, recording from as many neurons as possible in targeted brain regions with high spatial and temporal precision and over multiple spatial and temporal scales. While ad ...

    SBIR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  5. Photo-mediated ultrasound therapy for treatment of cutaneous vascular malformations

    SBC: PHOTOSONOX LLC            Topic: NIBIB

    ABSTRACT: Cutaneous vascular malformations (CVM), such as port wine stain (PWS) which occurs in 0.3–0.5% of newborns, are often a cause of great concern to patients for both medical and cosmetic reasons. Laser irradiation with flashlamp-pumped pulsed dye lasers, i.e. photothermolysis therapy (PTT), is currently the gold standard treatment for PWS. Most patients with PWS, however, fail to clear c ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  6. Real-time Multimodal Diffuse Reflectance and Polarization Imaging Based Nerve Identification in Surgical Field of View

    SBC: YAYA SCIENTIFIC LLC            Topic: NIBIB

    PROJECT SUMMARY We propose to develop a novel non-contact, label-free multimodality imager that provides real-time intraoperative identification of nerves within the surgical field-of-view to facilitate the prevention of unintended nerve damage (termed iatrogenic nerve injury) during surgical procedures, as they are a major source of postsurgical complications, e.g., chronic pain. In the United St ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  7. Development of Smart Flocculants for the Treatment of PFAS Contaminated Water

    SBC: BLUEGRASS ADVANCED MATERIALS, LLC            Topic: NIEHS

    Project Summary Per- and polyfluoroalkyl substances (PFAS) are a family of manmade congeners with dual hydro- and oleo- phobic properties, which is why they have been widely used in firefighting foams, as well as in a multitude of other products such as food packaging, paints, pesticides, and microelectronics. Given their extensive use, high water solubility, and resistance to conventional wastewa ...

    SBIR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  8. Feasibility study of developing SEAK-114 for the treatment of pediatric cancers

    SBC: SEAK Therapeutics, LLC            Topic: 102

    PROJECT SUMMARYAcute lymphoblastic leukemia (ALL) and neuroblastoma (NB) are the most common cancers in children. Currently treatment options are often associated with severe side effects. Therefore, there is a strong unmet medical need to develop targeted-drugs with higher therapeutic indexes for improved treatment outcome.Both MDM2 and XIAP are important cell-survival proteins in tumors. Elevate ...

    SBIR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  9. Point-of-Care CT Perfusion (PoC CT-P) for Early Stroke Assessment

    SBC: Xoran Technologies LLC            Topic: 101

    Abstract The goal of this SBIR Phase I project is to develop a portable and affordable cranial x-ray-based Computed Tomography Perfusion (CT-P) device for expedited front-line evaluation and triage of ischemic cerebral stroke victims. CT-P is the gold standard modality for assessment and classifying stroke patients to determine the best candidates for revascularizing procedures; however, CT-P is g ...

    SBIR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  10. Learning Health System Building Blocks: Filling Gaps to Enable a Real Time Physician-AI Partnership

    SBC: Prediction Health Inc.            Topic: NLM

    PROJECT SUMMARY/ABSTRACT Over 54% of doctors are experiencing burnout and the primary cause is documentation. Doctors spend up to two hours on clerical work for each hour of direct patient care. Documentation burden is the number one contributor to burnout, which costs the US health care system approximately $150 billion each year. Further, the largely free-text notes generated by healthcare provi ...

    SBIR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
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