You are here
Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
-
Receptors, Ligands, and Catalysts on Demand using Expanded Genetic Alphabets
SBC: FIREBIRD BIOMOLECULAR SCIENCES LLC Topic: 100DESCRIPTION provided by applicant Technology to deliver molecules andquot on demandandquot that bind to targets or catalyze reactions of a technologistandapos s choosing would have enormous commercial value in research manufacturing and medicine Thus this has been a andquot holy grailandquot of molecular science for a half century Even today chemical theory is inadequate to support de ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
RSK3 Anchoring Disruptor Therapy for Heart Failure
SBC: ANCHORED RSK3 INHIBITORS, LLC Topic: NHLBIDESCRIPTION provided by applicant Pathological cardiac remodeling including myocyte hypertrophy and apoptosis and myocardial interstitial fibrosis constitutes a common pathway to heart failure in disease Despite current pharmacologic therapy and other advances that attenuate remodeling mortality due to heart failure remains high New more effective therapeutic options are desperately neede ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
A Low Cost, Quantitative, Chemical Specific Device for Illicit Drug Detection
SBC: MKS Technology Topic: NIDADESCRIPTION provided by applicant This proposal will assess the quantitative capabilities of surface enhanced Raman scattering SERS detection of cocaine and marijuana metabolites in urine samples Combining low cost instrumentation and novel chemical sensing provides an innovative new approach for diagnosing illicit drug use Current methods use a colorimetric indicator to screen specimens fo ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Novel piperazine tethered thiazole compounds as antimalarials
SBC: Smart Biomolecules, Inc. Topic: NIAIDDESCRIPTION provided by applicant In spite of all the advances in molecular medicine malaria still afflicts about million people worldwide and half of the world population is at rik The disease causes nearly million deaths each year mostly children Unfortunately the prospects for control of malaria by chemotherapy have been seriously compromised by the emergence of resistance to all av ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Targeting CD137L to MC1R-Expressing Melanoma Cells and Tumors.
SBC: MODULATION THERAPEUTICS, INC. Topic: 102DESCRIPTION provided by applicant There are specific high affinity ligands for receptors found on many cancers that have been investigated as imaging probes and we believe that we should try to enhance immunotherapy by using these ligands to deliver immune effectors to the cancer microenvironment Melanoma is among the most immunogenic tumors known and so that disease is an excellent test bed f ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Simple Inexpensive Assay for Five Common HIV Resistance Mutations
SBC: FIREBIRD BIOMOLECULAR SCIENCES LLC Topic: NIAIDDESCRIPTION provided by applicant Only a few inexpensive drugs can be used in the developing world for the treatment of AIDS Several of these target the HIV reverse transcriptase RT Accordingly patient therapy with these drugs often fails when the gene encoding RT undergoes mutation Thus the WHO recently reported that after months of treatment with anti RT drugs patients most often r ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Therapeutic Neutralization of the Inflammasome After Spinal Cord Injury
SBC: INFLAMACORE LIMITED LIABILITY COMPANY Topic: 105DESCRIPTION provided by applicant Spinal cord injury SCI is a complex and devastating clinical condition mediated by proinflammatory cytokines that produce neuronal loss axonal destruction and demyelination during the secondary injury cascade There are currently no proven therapies targeting posttraumatic inflammation that have been shown to have clinical value We have previously shown th ...
STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health -
A Hidden Markov Model Based Segmentation Framework for MR Spectroscopy Imaging
SBC: INFOTECH SOFT, INC. Topic: N/ADESCRIPTION (provided by applicant): The convergence of biomedicine and computation in the form of biomedical computing has demonstrated gains in the areas of genetic sequences, biomedical images, qualitative descriptors for health and social science and geospatial images and chemical formulae. This provides a unique opportunity to utilize novel image processing techniques to more accurately and o ...
STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health -
Cell Culture Production of Marine-Derived Bioactive Terpenses
SBC: Nautilus Topic: N/ADESCRIPTION (provided by applicant): The marine environment has proven to be a prolific source of novel bioactive molecules with great potential in a number of therapeutic areas. Currently, marine natural products are in clinical trials for cancer, analgesia, allergy and cognitive diseases. It is clear that research groups will continue to identify new marine natural products which offer great po ...
STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health -
Non-Peptide Somatostatin Agonist Analgesics
SBC: RFE PHARMA, INC. Topic: N/ADESCRIPTION (provided by applicant): Endogenous somatostatin receptors (SSTRs) offer novel targets for treating pain via both peripheral and central mechanisms. Our studies show that peripheral SSTR activation prevents nociceptor sensitization and provides phasic and tonic inhibitory control of nociceptors. This modulation is an important therapeutic goal since sensitization of peripheral nocicept ...
STTR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health