Award Data

DESCRIPTIONprovided by applicantPeople in recovery from serious mental illness are often excluded from making decisions about their own mental health carefrequently resulting in poor alliances with their care providersWhile the Patient Protection and Affordable Care Act addresses this issue by requiring programs to be person centered and recovery orientedproviders often struggle to identify concre ...

DESCRIPTIONprovided by applicantTherapeutic Reversal of Endothelial Dysfunction in Atherogenesis Cardiovascular disease is the leading cause of morbidity and mortality in the worldIn particularatherosclerosis is a life threatening disease strongly associated with risk factors such as elevated cholesterol levelshigh blood pressure and diabetesThere are effective commercially available therapeutics ...

DESCRIPTION provided by applicant In the andquot Enhancing Confidentiality of Research Files Based on Medicare Dataandquot project Acumen LLC aims to expand the overall capabilities of researchers to use survey linked Medicare claims data Currently the process for obtaining approval from the Centers for Medicare andamp Medicaid Services CMS to access these files entails significant paper ...

DESCRIPTIONprovided by applicantThe goal of the project is to develop a therapeutic against vancomycin resistant enterococcusVREThese infections are a serious health concern because antibiotic resistance has gotten to the point where there are few or no effective treatment options availableFor the enterococciresistance is inherently linked to toleranceth ability of the pathogen to survive in the p ...

DESCRIPTION provided by applicant Obesity has reached epidemic proportions in the U S and plays a major role in the development of type diabetes dyslipidemia and cardiovascular disease There remains a very significant need for better non surgical treatments While most weight loss agents rely on suppressing appetite to reduce caloric intake strategies that can safely enhance energy expe ...

DESCRIPTION provided by applicant Neonatal seizures are a common neurologic diagnosis in the Neonatal Intensive Care Unit NICU occurring in some newborns annually in the US and are frequently associated with long term deleterious consequences including intellectual disability cerebral palsy epilepsy and other neurodevelopmental disabilities Early detection and treatment can resul ...

DESCRIPTIONprovided by applicantThe purpose of this project is to develop an improvedminimally invasive treatment for intracranial aneurysmsIntracranial aneurysms are spherical outpouchings of blood vessels in the head that result from weakness in the vessel wallUnruptured aneurysms are present in approximatelyof the general populationand rupture can be devastating with a high morbidity and mortal ...

ABSTRACT This project will harness recent technological developments in smart tablets and other mobile devicestheir proliferation and affordabilitytheir increased use in pedagogy and healthcareand the numerous benefits they affordsuch as personalizationconnectednessmobilityand improved learning outcomesThese developments will be leveraged to improve the uptakeappropriate implementationand evaluati ...

DESCRIPTION provided by applicant Alzheimerandapos s disease AD is one of the most significant public health problems of the st century with the number of patients in the US estimated to grow from million to million by and an annual cost of care projected to reach $ trillion Current treatments for AD have limited effect for a short duration and only serve to alleviate sympto ...

DESCRIPTIONprovided by applicantNeuron cell culture is widely used for studies in basic researchdrug discoveryand toxicity testingTraditional neuron cell culture approaches result in random growth of processes which prevent the study of their unique polarized morphologyOur goal is to provide robustuser friendlyand cost effective culture platforms to manipulate and access neurons and their subcellu ...