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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Serum Hepcidin Immunoassay: Laboratory to Marketplace

    SBC: INTRINSIC LIFESCIENCES LLC            Topic: 300

    DESCRIPTION provided by applicant Disorders of iron metabolism are among the most common human diseases During the last decade rapid progress has been made in understanding the molecular basis of iron homeostasis and its disorders The peptide hormone hepcidin has emerged as the master regulator of iron metabolism Dysregulation of hepcidin is the principal or contributing factor in most syst ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Risperidone Subcutaneous Implant

    SBC: Delpor, Inc            Topic: 101

    DESCRIPTION provided by applicant The objective of the proposed study is to develop a subcutaneous implant of risperidone which provides consistent therapeutic blood levels of the drug for months The benefits of such product include improved medication adherence the ability to withdraw the medication if needed due to treatment emergent Adverse Effects AEs fewer relapses and improved eff ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  3. A Human Fc Bifunctional Fusion Protein to Treat Severe Allergic Asthma

    SBC: TUNITAS THERAPEUTICS, INC.            Topic: NIAID

    DESCRIPTION provided by applicant The overall goal of this phase SBIR proposal is to position our novel biologic GE for human clinical trials in allergic disease though the completion of critical preclinical development research activities GE a genetically engineered human fusion protein consisting of portions of the human gamma Fc linked to portions of the human epsilon Fc chain has unique mechan ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  4. Arenavirus Antiviral Lead Optimization

    SBC: Arisan Therapeutics, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant Arenaviruses comprise a diverse family Several species are associated with severe arenaviral hemorrhagic fever AVHF in humans that exhibit case fatality rates as high as Human infection with arenaviruses typically occurs through contact with materials contaminated with the excretions of an infected rodent although direct human to human transmission may ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Advanced morphological analysis of cerebral blood flow for acute concussion diagnosis and return to play determination

    SBC: Neural Analytics, Inc.            Topic: 101

    Project Summary Abstract Between and million people each year suffer a mild TBI in the US alone Reliable diagnosis and prompt treatments are vital to managing the often serious short and long term sequelae resulting from mild TBI However a reliable objective and accurate method for mild TBI diagnosis outside of a hospital setting and in particular for determining RTP readiness has e ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  6. An immune based approach for HIV eradication

    SBC: RETROVIROX, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Viral reservoir eradication has become a leading subject in the field of HIV research A plethora of antiretrovirals ARVs are available to efficiently treat infection Living with HIV has become a chronic disease in which viral load can be controlled in over ninety percent of patients Yet the health social and economical burden of the disease are unpre ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  7. Clinical and Non Clinical Evaluations of repeat administrations of the FAST PV and mGFR Technology

    SBC: PHARMACOPHOTONICS, INC.            Topic: 400

    DESCRIPTION provided by applicant Pharmaco Photonics DBA FAST Biomedical proposes a PHASE IIB project to determine the safety and functionality of repeat administration of the FAST PV and mGFR Technology in both non clinical and clinical studies The long term goal of this SBIR project is to test FASTandapos s fluorescent based test in humans and commercializes this product for rapid detecti ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  8. Therapeutic Antibodies for CMV

    SBC: Trellis Bioscience, LLC            Topic: NIAID

    DESCRIPTION provided by applicant Human cytomegalovirus HCMV is the major viral cause of birth defects and of medical complications associated with organ transplantation Passive immunization using human immune globulin HIG has been shown to prevent disease As pooled plasma however HIG is a variable product that potentially contains infectious agents or may cause side effects Native human monoclona ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  9. Cyanalyzer A Medical Laboratory Device for the Rapid Diagnosis of Cyanide Exposure

    SBC: SEACOAST SCIENCE, INC.            Topic: 106

    Project Summary The overall objective in the proposed project is to develop and test a prototype Cyanalyzer sensor designed for the rapid and accurate diagnosis of cyanide exposure The proposed device directly addresses a long term goal of the National Institute of Neurological Disorders and Stroke NIH Countermeasures Against Chemical Threats CounterACT program development of rapid diagnostic ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Strain Independent Therapeutic Antibodies for Influenza

    SBC: Trellis Bioscience, LLC            Topic: NIAID

    DESCRIPTION provided by applicant Trellis Bioscienceandapos s CellSpotandquot technology for identification of rare human antibodies with high specificity and affinity against multiple antigen has enabled discovery of highly efficacious strain independent antibodies to Respiratory Syncytial Virus and to Cytomegalovirus We have now applied CellSpot to isolate two native human antibodies with ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health

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