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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Integrated Cookstove-Heating-Electricity Generation for Small homes- Integrated cooking, heating, and electric power generation

    SBC: ASAT, INC.            Topic: 15NCER02

    _x000D_Currently available biomass heating/cooking stoves in Asia and in the USA do not efficiently cook food or heat houses while consuming too much fuel and emitting pollution, resulting in respiratory illnesses and premature death. ASAT specializes in the development and manufacturing of clean burning biomass stoves. In SBIR Phase I, ASAT developed a low emission, fuel efficient Integrated Heat ...

    SBIR Phase II 2017 Environmental Protection Agency
  2. Developing a novel therapy for diabetic retinopathy

    SBC: Everglades Biopharma, LLC            Topic: W

    Project Summary Diabetic retinopathy DR is a leading cause of vision loss affecting about million people worldwide A major breakthrough in DR therapy is the recent approval of vascular endothelial growth factor VEGF inhibitors However anti VEGF therapy has limited efficacy with a number of side effects The critical barrier is how to identify other angiogenic targets for alternative or ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. A Randomized Blinded Placebo Controlled Clinical Trial to Evaluate Longeveron Mesenchymal Stem Cell LMSC Therapy for Treating The Metabolic Syndrome

    SBC: Longeveron LLC            Topic: NIA

    The metabolic syndrome MetS is a cluster of factors that increases the risks for cardiovascular disease type diabetes mellitus and mortality and currently affects andgt of US adults MetS is associated with endothelial dysfunction decreased circulating endothelial progenitor cells EPCs and a pro inflammatory state We have made the exciting discovery that therapy with allogeneic me ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Commercialization of a Novel Therapeutic for Alzheimer's Disease

    SBC: CoPlex Therapeutics, LLC            Topic: NIA

    ABSTRACT Traditional mon therapeutictarget driven approaches to drug development for Alzheimer s diseaseADare becoming increasingly expensive and in many cases disappointingly unsuccessfulBased on preliminary in vitro and in vivo studies we have identified a novel small moleculemethyldimethyloxodihydrobenzo cnaphthyridinecarboxylateBNCthat significantly decreases neuroinflammation and production o ...

    STTR Phase II 2017 Department of Health and Human Services
  5. Exosomal Drug Delivery

    SBC: 3P BIOTECHNOLOGIES, INC.            Topic: 102

    Technical AbstractAs with many chemotherapeutic drugstaxanes exhibit poor oral bioavailabilityhencethey are administered intravenouslyi vThis regimen results in significant toxicitiesdue to both the high drug dose and vehicleCremophore ELRusedAttempts made to develop an oral chemotherapeuticusing liposomes and polymeric nanoparticles as carriershave not made it to the clinicdue to their inherent l ...

    SBIR Phase II 2017 Department of Health and Human Services
  6. STEM Familia A language acquisition mobile app to improve long term educational and health outcomes among Latino families

    SBC: Oregon Research Behavioral Intervention Strategies, INC            Topic: NIMHD

    PROJECT SUMMARY ABSTRACT STEM Familia A language acquisition mobile app to improve long term educational and health outcomes among Latino families Enhancing the STEM science technology engineering and math proficiency of Hispanic elementary students to prepare them for success in secondary school and college STEM courses and in STEM fields after graduation While STEM fields account for mo ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Culturally Responsive Stress Reduction A Mobile Mindfulness Application to Support Health Promotion for African Americans

    SBC: IRIS MEDIA INC            Topic: 102

    ABSTRACT The proposed intervention Culturally Responsible Stress Reduction A Mobile Mindfulness Application to Support Health Promotion for African Americans CRSR is designed to encourage the use of mindfulness to mitigate the disproportionate amount of stress related health disparities facing African Americans Current mindfulness approaches have been unsuccessful in engaging this popula ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Probabilistic Modeling for Software Guided Radiotherapy Patient Plan QA

    SBC: SUN NUCLEAR CORP.            Topic: 103

    Errors in the planning and delivery of radiation therapy can result in inferior outcomes for patients The magnitude of this problem is now well appreciated from cooperative group trials and other sources At present however there are few concrete tools to reduce the chance of plan errors passing undetected Current practice uses a variety of error mitigation means such as human inspection of th ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Optimizing electrical impedance myography outcomes through data mining

    SBC: Myolex Inc            Topic: NIAMS

    Project summary Electrical impedance myography EIM is a non invasive technology for the assessment of muscle that is based on the application of a weak high frequency electrical current to a muscle and the measurement of the resulting surface voltages The further development and application of EIM remains the main business focus of Skulpt Inc a small business concern based in Boston and San ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Novel fluorescent protein expression vector that simplifies the solubilization of membrane proteins

    SBC: PARATECHS CORP.            Topic: 300

    ABSTRACT Simple protein mutations can have serious consequences by causing diseases that affect peopleandapos s lives Protein therapeutics are developed to target and replace those protein mutations and essentially to heal the disease Distinctively membrane proteins make up over of todayandapos s drug targets However cumbersome time consuming and often ineffectual purification methods ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health

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