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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Integrated Cookstove-Heating-Electricity Generation for Small homes- Integrated cooking, heating, and electric power generation

    SBC: ASAT, INC.            Topic: 15NCER02

    _x000D_Currently available biomass heating/cooking stoves in Asia and in the USA do not efficiently cook food or heat houses while consuming too much fuel and emitting pollution, resulting in respiratory illnesses and premature death. ASAT specializes in the development and manufacturing of clean burning biomass stoves. In SBIR Phase I, ASAT developed a low emission, fuel efficient Integrated Heat ...

    SBIR Phase II 2017 Environmental Protection Agency
  2. Developing a novel therapy for diabetic retinopathy

    SBC: EVERGLADES BIOPHARMA LLC            Topic: W

    Project Summary Diabetic retinopathy DR is a leading cause of vision loss affecting about million people worldwide A major breakthrough in DR therapy is the recent approval of vascular endothelial growth factor VEGF inhibitors However anti VEGF therapy has limited efficacy with a number of side effects The critical barrier is how to identify other angiogenic targets for alternative or ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. A Randomized Blinded Placebo Controlled Clinical Trial to Evaluate Longeveron Mesenchymal Stem Cell LMSC Therapy for Treating The Metabolic Syndrome

    SBC: Longeveron LLC            Topic: NIA

    The metabolic syndrome MetS is a cluster of factors that increases the risks for cardiovascular disease type diabetes mellitus and mortality and currently affects andgt of US adults MetS is associated with endothelial dysfunction decreased circulating endothelial progenitor cells EPCs and a pro inflammatory state We have made the exciting discovery that therapy with allogeneic me ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Commercialization of a Novel Therapeutic for Alzheimer's Disease

    SBC: CoPlex Therapeutics, LLC            Topic: NIA

    ABSTRACT Traditional mon therapeutictarget driven approaches to drug development for Alzheimer s diseaseADare becoming increasingly expensive and in many cases disappointingly unsuccessfulBased on preliminary in vitro and in vivo studies we have identified a novel small moleculemethyldimethyloxodihydrobenzo cnaphthyridinecarboxylateBNCthat significantly decreases neuroinflammation and production o ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Topical Eyedrop Therapy for Keratoconus

    SBC: Iveena Delivery Systems, Inc.            Topic: N

    Project Summary Keratoconus KCN is a progressive disorder associated with structural changes in corneal collagen organization that leads to corneal thinning and ruptures in Bowman s layer and or Descemet s membrane As the disease progresses it leads to irregular astigmatism progressive myopia and subsequently poor visual acuity Treatment options are surprisingly limited with no oral or topi ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Exosomal Drug Delivery

    SBC: 3P BIOTECHNOLOGIES, INC.            Topic: 102

    Technical AbstractAs with many chemotherapeutic drugstaxanes exhibit poor oral bioavailabilityhencethey are administered intravenouslyi vThis regimen results in significant toxicitiesdue to both the high drug dose and vehicleCremophore ELRusedAttempts made to develop an oral chemotherapeuticusing liposomes and polymeric nanoparticles as carriershave not made it to the clinicdue to their inherent l ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  7. STEM Familia A language acquisition mobile app to improve long term educational and health outcomes among Latino families

    SBC: OREGON RESEARCH BEHAVIORAL INTERVENTION STRATEGIES, INC.            Topic: NIMHD

    PROJECT SUMMARY ABSTRACT STEM Familia A language acquisition mobile app to improve long term educational and health outcomes among Latino families Enhancing the STEM science technology engineering and math proficiency of Hispanic elementary students to prepare them for success in secondary school and college STEM courses and in STEM fields after graduation While STEM fields account for mo ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Cone Beam Tomosynthesis Fluoroscopy for Image Guided Interventions

    SBC: NVIEW MEDICAL            Topic: NCI

    PROJECT SUMMARY ABSTRACT nView medicalSurgical inaccuracies impact patient safety and increase healthcare costsSpinal fusions are a prime examplewithprocedures per year in the US it is the sixth most frequent procedure and reoperation rates areThereareanestimatedrevisionsurgeriesduetomisplacedscrewsthatcouldbeavoidedifintraoperativeD guidance was standardThe total cost of the revision surgeries du ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Culturally Responsive Stress Reduction A Mobile Mindfulness Application to Support Health Promotion for African Americans

    SBC: IRIS MEDIA INC            Topic: 102

    ABSTRACT The proposed intervention Culturally Responsible Stress Reduction A Mobile Mindfulness Application to Support Health Promotion for African Americans CRSR is designed to encourage the use of mindfulness to mitigate the disproportionate amount of stress related health disparities facing African Americans Current mindfulness approaches have been unsuccessful in engaging this popula ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Clinical Development of JS-K for the Treatment of Cancer

    SBC: JSK THERAPEUTICS INC.            Topic: 102

    PROJECT DESCRIPTIONJSK TherapeuticsJSKTDirect to Phase II Application Nitric oxideNOis a potentially powerful therapy against cancerSpontaneous NO generating drugs cannot be used to treat malignancies because of the pleiotropic effects of NOIn particularNO is a potent vasodilator with resultant hypotensionIn order to make NO based cancer therapy possibleit is necessary to develop agents that deliv ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
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