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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A Biocatalytic Route to Nitrile Reduction

    SBC: QUZYME, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The recently identified ykvM gene family encodes an enzyme belonging to a unique family of nitrile oxido-reductases that catalyze the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine, a transformation never before observed in biology. Nitrile containing compounds are ubiquitous in the pharmaceutical, agricultural, and chemical industries, wh ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  2. Accessible Graphical Display for Numberical Data

    SBC: VIEWPLUS TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The long-term goal of this proposed project is a commercial technology permitting mainstream authors easily to create and distribute a wide variety of one and two dimensional data plots that are easily accessible by all people including those who are blind or have other print disabilities. This would extend the ViewPlus IVEO technology to include virtually all ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  3. A Cognitive-Behavioral Multimedia Internet Program to Prevent Youth Depression

    SBC: Oregon Center For Applied Science, Inc            Topic: N/A

    DESCRIPTION (provided by applicant): Depression is one of the most prevalent mental disorders to afflict adolescents. It seriously impacts role functioning and typically takes a recurrent or chronic course. Because most depressed youth never receive treatment, there is a critical need to develop effective prevention programs that can be easily implemented and widely disseminated. The proposed proj ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  4. A computational platform to prioritize drugs and target genes for therapeutic intervention

    SBC: Genetic Networks, LLC            Topic: NCATS

    Project Summary This project proposes implementation of a computational discovery platform that quantifiably identifies and prioritizes both targets and compounds for therapeutic intervention This platform is based on a novel fusion of two state of the art computational approaches phenolog mapping and functional networks with proprietary data from our powerful gene drug screening assays HIP H ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. A counterpulsation device to promote myocardial recovery

    SBC: SCR, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The incidence of congestive heart failure (CHF) is increasing worldwide with over one million new cases diagnosed annually. Over the past 30 years, counterpulsation with an intra-aortic balloon pump (IABP) has been widely and successfully used as a short-term treatment for cardiac dysfunction. However, counterpulsation is limited by its location within the desc ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  6. ACOUSTIC OPTICS FOR MICROSCOPY

    SBC: Neos Technolgies, Inc.            Topic: N/A

    DESCRIPTION (Adapted from Applicant's Abstract): This is a Phase I SBIR application to develop an add on system for fluorescence microscopes to provide control over the incident wavelength and to provide accurate spectral analysis and discrimination of spectral bands in image space. This will be accomplished without moving parts at high speed using improved acousto-optic devises. The proposal foc ...

    SBIR Phase I 1997 Department of Health and Human Services
  7. A Cytomegalovirus based therapeutic vaccine for chronic hepatitis B

    SBC: TOMEGAVAX, INC.            Topic: R

    Abstract Although an efficient prophylactic vaccine is available for hepatitis B virus HBV chronic hepatitis B CHB affects up to million people worldwide and despite advances remains mostly incurable In adults acute HBV infection is cleared in of cases by CD T cell mediated mechanisms but chronic lifelong infection ensues in the remaining individuals which can lead to liver ci ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. ADVANCED LABORATORY SYSTEM FOR PSYCHOPHYSIOLOGY

    SBC: United States Control            Topic: N/A

    WE EILL DEVELOP A WIRELESS DIGITAL POLYGRAPH LINK WITH SOPHISTICATED DIGITAL ERROR CORRECTION, WHICH WILL PROTECT TRANSMITTED PHYSIOLOGICAL MEASUREMENT SIGNALS FROM NOISE DEGRADATION AND FROM DROPOUTS CAUSED BY SUBJECTS MOVING AROUND WHILE THEY ARE BEING MONITORED. WE WILL ADD THE WIRELESS DIGITAL LINK TO A MINIATURE, BATTERY-OPERATED 16-CHANNEL MICROPROCESSOR-BASED DIGITAL POLYGRAPH PREVIOUSLY DE ...

    SBIR Phase II 1993 Department of Health and Human Services
  9. A Hidden Markov Model Based Segmentation Framework for MR Spectroscopy Imaging

    SBC: INFOTECH SOFT, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The convergence of biomedicine and computation in the form of biomedical computing has demonstrated gains in the areas of genetic sequences, biomedical images, qualitative descriptors for health and social science and geospatial images and chemical formulae. This provides a unique opportunity to utilize novel image processing techniques to more accurately and o ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  10. A Hidden Markov Model Based Segmentation Framework for MR Spectroscopy Imaging

    SBC: INFOTECH SOFT, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The convergence of biomedicine and computation in the form of biomedical computing has demonstrated gains in the areas of genetic sequences, biomedical images, qualitative descriptors for health and social science and geospatial images and chemical formulae. This provides a unique opportunity to utilize novel image processing techniques to more accurately and o ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
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