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The Award database is continually updated throughout the year. As a result, data for FY22 is not expected to be complete until September, 2023.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Bactericidal antibiotic for Vancomycin Resistant Enterococci

    SBC: Arietis Corporation            Topic: NIAID

    DESCRIPTIONprovided by applicantThe goal of the project is to develop a therapeutic against vancomycin resistant enterococcusVREThese infections are a serious health concern because antibiotic resistance has gotten to the point where there are few or no effective treatment options availableFor the enterococciresistance is inherently linked to toleranceth ability of the pathogen to survive in the p ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Development of BA for treatment of cerebral cavernous malformation

    SBC: BIOAXONE BIOSCIENCES, INC.            Topic: 105

    DESCRIPTION provided by applicant Cerebral cavernous malformations CCMs also known as andapos cavernous angiomaandapos or andapos cavernomaandapos are common vascular abnormalities found in of the population exposing patients to a lifetime risk of hemorrhagic stroke seizures and other neurologic sequelae Approximately of CCM lesions present with clinically overt hemorr ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  3. STAT Palm-Sized Blood Counter

    SBC: CHAN RESEARCH, LLC            Topic: NHLBI

    DESCRIPTIONprovided by applicantThe overarching objective of this proposal is to attain data for FDAksubmission of a handheld miniaturized STAT Blood Counter usingL blood to yield a complete blood countCBCwithpart differentialThis dramatically decreased size and sample volume creates new opportunities in delivery of these hematology testsultimately leading to more streamlinedavailableand on demand ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Arrayed drug microinjection for guiding precision medicine in relapsed lymphoma

    SBC: PRESAGE BIOSCIENCES, INC.            Topic: 102

    DESCRIPTIONprovided by applicantImprovements in cancer diagnostics and therapeutics have positively impacted outcomes for oncology patients within select clinical nichesHoweversignificant therapeutic uncertainty awaits the majority of today s oncology patients who present in the clinic with cancer that will relapse after exhibiting an initial response or whose cancer is already refractory to stand ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Advanced morphological analysis of cerebral blood flow for acute concussion diagnosis and return to play determination

    SBC: Neural Analytics, Inc.            Topic: 101

    Project Summary Abstract Between and million people each year suffer a mild TBI in the US alone Reliable diagnosis and prompt treatments are vital to managing the often serious short and long term sequelae resulting from mild TBI However a reliable objective and accurate method for mild TBI diagnosis outside of a hospital setting and in particular for determining RTP readiness has e ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  6. Arenavirus Antiviral Lead Optimization

    SBC: Arisan Therapeutics, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant Arenaviruses comprise a diverse family Several species are associated with severe arenaviral hemorrhagic fever AVHF in humans that exhibit case fatality rates as high as Human infection with arenaviruses typically occurs through contact with materials contaminated with the excretions of an infected rodent although direct human to human transmission may ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  7. IGF OT IGF SBIR TOPIC FAST TRACK BASE PHASE I LINE ITEM CERCLAGE FOR TREATING SECONDARY MITRAL REGURGITATION

    SBC: TRANSMURAL SYSTEMS LLC            Topic: NHLBI

    Development of Transcatheter Cerclage Mitral Valve Annuloplasty Cerclage

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  8. IGF OT IGF TRANSCATHETER CAVOPULMONARY BYPASS ENDOGRAFT SBIR TOPIC DIRECT TO PHASE II IGF OT IGF

    SBC: TRANSMURAL SYSTEMS LLC            Topic: NHLBI

    Extra anatomic bypass or vascular shunts divert blood flow In congenital heart disease these surgical procedures are critical for management Children born with one functional ventricle or cardiac pumping chamber require two to three major cardiac surgery procedures for palliation The management goal is to divert systemic venous return deoxygenated blood from the heart directly to pulmonary a ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Near patient molecular diagnostics test for infections

    SBC: GeneFluidics, Inc.            Topic: R

    ABSTRACT Currentlythere are no FDA cleared molecular based tests for urinary tract infectionUTIpathogen identification and antimicrobial susceptibility testing to replace the andapos gold standardandaposof dipstick urinalysis and urine culturingAll pathogen identification tests still rely on clinical isolates from urine cultureslargely unchanged from Kochandapos s postulates developed in theth cen ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Rapid Immunodiagnosis of Drug-Resistant Bacterial Pathogens

    SBC: SILVER LAKE RESEARCH CORPORATION            Topic: NIAID

    PROJECT SUMMARY ABSTRACT This proposal describes Phase II of the development of a rapid immunoassay test kit for the determination oflactam antibiotic resistanceto be used as a point of care diagnostic test for urinary tract infectionsTodayantibiotics for UTI are prescribed empiricallywith no diagnostics available to clinicians to avoid treating resistant infections with the very drug to which the ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
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