Award Data

Over 2.7 million units of plasma are transfused annually in the United States mainly to treat trauma, shock, burn injury, and emergency surgery. Plasma from AB individuals, often referred to as universal plasma, is in high demand for both military and civilian emergency transfusions as it does not contain anti-A and anti-B antibodies that could induce fatal hemolytic reactions as a result of their ...

This project will achieve a field-deployable system to estimate circadian phase. Our approach involves the use of minimally-invasive sensors suitable for use in operational environments to continuously monitor physiological parameters associated with slee

In resource limited settings, rapid and accurate diagnosis of infections is critical for managing potential exposures to highly virulent pathogens, whether occurring from an act of bioterrorism or a natural event. This is especially important for hard to detect intracellular bacterial and alphavirus infections, that overlap symptomatically and often treated empirically due to a lack of reliable an ...

This project involves the development of a deep-fitting in-ear personal noise dosimeter that can be worn for at least 72 hours without removal. The purpose of this device is to measure noise exposure deep in the ear canal, near the tympanic membrane. The dosimeter must be compatible with conventional hearing protection, i.e., earplugs and/or earmuffs can be worn with the device in-place without ad ...

Department of Defense personnel must wear respiratory protection continuously when deployed in regions with the danger of chemical or biological attack. Manufacturing respirators/masks using conventional molding methods limits the features that can be designed into the protection. Additive manufacturing provides an ideal approach for manufacturing respirators. Additive Manufacturing enables the ab ...

A significant performance gap exists between the theoretical number of Floating Point Operations (FLOPS) that an HPC machine is capable of sustaining and the number of FLOPS realized by real-world HPC software. One of the principal reasons for this gap is the parasitic work that computational processes must do to communicate with one another. It has been shown that this communication work can be s ...

Iron deficiency is one of the most common nutritional deficiencies in the United States. Left untreated, iron stores continue to deplete, resulting in iron deficiency anemia (IDA). Women undergoing basic military training are particularly susceptible to reduced and depleted iron stores. To-date, there are no point-of-care (POC) instruments for comprehensive, accurate determination of iron status. ...

Typical procedures for respirator masks sizing and protective fit test are time-consuming and user intensive, requiring taking anthropometricmeasurements of the wearer, sampling the wearers breathing zone and the use of specialized tools and equipment. The proposed softwareapp aims to quickly, accurately and automatically perform respirator mask sizing and predict protective fit using only 2D imag ...

SuperChemVR is a room-scale VR lab and learning game for high school chemistry students. While wearing a VR headset, students will be immersed in a simulated chemistry 3D-environment where they will be challenged to acquire basic lab and safety skills. Through actual, accurate measurement and experimentation, students will improve their understanding of chemistry practices as they learn using scie ...

This project is a unique metagenomic evaluation of under-studied extremophilic microbiome natural products (NPs), with the goal of discovering novel antibiotic biowarfare agent (BWA) countermeasures. A metagenomic biosynthetic gene cluster library from extremophilic sources was created, sequenced, analyzed, and exploited to produce several broad-spectrum antibiotic extracts during the Phase I effo ...