Award Data

GeneCapture is proposing to use its rapid CAPTURE assay (Confirm Active Pathogens Through Unamplified RNA Expression) to identify the pathogen(s) in wound infections. The pathogen Infection Diagnostic (ID)test takes place in a disposable cartridge that integrates and automates the sample prep steps and determines the genetic signature of the pathogens present. The assay is based on immobilized ste ...

Functional Fluidics is dedicated to commercialization of novel assays for improved blood cell health and function assessment. Cardiovascular Disease (CVD) is the leading cause of death in the United States with Heart Disease (HD) accounting for over 75% of all 840,678 deaths attributed to CVD in 2016. Mechanical Circulatory Support (MCS) devices provide cardiac and systemic support and reduce morb ...

Response to National Institutes of Health Small Business Innovation Research (SBIR)NIH SBIR: PHS 2019-2 Omnibus Solicitation for SBIR/STTR Grant Applications Re : Submission of R43/44 SBIR Phase I Proposal FOA : PHS 2019-2 Omnibus Solicitation of the NIH, CDC, FDS and ACF for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44]) Institute/Division/Topic : National Institute ...

In resource limited settings, rapid and accurate diagnosis of infections is critical for managing potential exposures to highly virulent pathogens, whether occurring from an act of bioterrorism or a natural event. This is especially important for hard to detect intracellular bacterial and alphavirus infections, that overlap symptomatically and often treated empirically due to a lack of reliable an ...

While this solicitation described the need for better sampling methods and rugged mass spectrometers, the topic author funded our alternative approach, which employs existing DoD Raman spectrometers. The Phase III project goal is to develop a Field-Usable Designer Drug Analyzer capable of identifying and quantifying drugs in saliva and blood at 10 ng/mL in 10 minutes. Feasibility was demonstrated ...

Eye injuries are common in combat. Many of these injuries can result in a buildup of pressure behind the eye, causing a damaging reduction in blood flow to the retina and optic nerve. A Lateral Canthotomy and Cantholysis (LCC) can save the eyesight of t

Blood loss is a major problem in trauma care and resuscitation, causing over 90% of potentially survivable combat deaths. Dried blood products that can be stored at ambient temperatures and rapidly rehydrated for transfusions offer significant potential t

Check-in Check-out (CICO) is a widely used behavioral intervention for elementary and middle schools centered on goals, feedback, and communication with parents about daily behavioral performance. This project will develop a prototype platform to streamline and automate the delivery of CICO. The prototype will include an app, a user-friendly interface, and a dashboard to track progress and capture ...

In a previous National Science Foundation SBIR project, the developer created an online platform that uses songs to support mathematical learning. In the current project, the team will develop a prototype of a component of a platform to guide students in creating and producing their own music videos about algebra. The prototype will include a video production application, features to enhance learn ...

This project will develop an augmented reality application to generate personalized formative assessment feedback as students interact with physical objects related to STEM (science, technology, engineering, and math) concepts, such as recognizing the shape of an atom. The prototype will be designed as a multi-sensory tool to support students with visual challenges. At the end of Phase I, in a res ...