Award Data

With the advent of high-density low-power sub-20nm technology processes and circuits with tens-of-billions of transistors, radiation-induced single-event effects present a new set of design challenges for terrestrial applications. Developing reliable single-event effect resilient microelectronics in these modern technology nodes is a resource and time-intensive endeavor that further requires valid ...

To address the scarcity of effective treatments for volumetric muscle loss injuries, we propose a novel aligned multilumen nanofibrillar collagen scaffold loaded with Hepatocyte Growth Factor (HGF) modified messenger RNA (mmRNA) to direct functional muscl

There has been considerable interest in the development of alternative therapies for pain management that are neither opioid nor non-steroidal anti-inflammatory drugs (NSAIDs). Kalyra Pharmaceuticals has demonstrated that acetaminophen, also known as APAP

This proposal is for a subsequent Phase II for the SBIR project Apps for Rapid Epidemiological Surveillance (AREA).Our Phase II accomplishments focused on AREA handheld apps and their use for managing epidemiological data acquisition.Our proposed subsequent Phase II effort will increase the AREA capabilities for data stream integration and decision support by extending the system to a Disease Outb ...

Despite recent tremendous leaps in the development of new technologies for image recording, presentation, manipulation, 3D capabilities, and analysis, many vision exams are still performed using paper Snellen charts, paper color charts and Amsler grids. Current procedures are time consuming, labor intensive, potentially subject to transcription errors and test preparation, which may compromise the ...

Existing visual screening devices consist of illuminated test cards. By rotating the knob, images may be changed; however, once the system is loaded with cards it cannot be easily reconfigured. There are a limited number of cards that a unit can hold at one time, and it is impossible to change cards on the fly if a patients vision needs further investigation or if the clinician wants to do variabl ...

Over 820 million Indians, about 65% of its population, cook on polluting open fires, causing ~1 million premature deaths annually. Fifty million households have no electricity. The Power Stove is a household energy solution combining clean cooking and reliable, ondemand power. Clean combustion and thermoelectric power technology, make it a high performance, user desirable solution based on low cos ...

Rapid diagnosis in conflict areas is a growingmilitary need, as troops areexposed to chemical threats (http://www.army.mil/e2/c/downloads/351235.pdf). Testingfor biomarkers in saliva has recently shown great promisein diagnostics, prognostics, and treatmentefficacy follow-up. In addition to itsconveniencefor field sampling and rapid testing,saliva is a rich body fluid with a number of physiologica ...

The project team will develop a platform that will facilitate design challenges in K-12 classrooms across STEM academic topics and career paths within the field of engineering. The platform will enable classes to post their projects to the site and for other classes around the country to participate in the project. Each challenge (and the associated education resources curated for that challenge) ...

Combat soldiers are exposed to vast numbers of dangerous chemicals with potentially adverse health outcomes. This SBIR proposal aims to develop a new class of saliva based diagnostic assays that will measure the bodys response to toxic chemical exposure with a panel of clinically validated biomarkers that are indicative of organ injury. The tests will leverage the proven functionality of lateral ...