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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Technology for Sterile Water Generator

    SBC: TDA RESEARCH, INC.            Topic: DHP16007

    Currently, deployed medics must transport, maintain and be resupplied with liquid-based medications and materials that are heavy, expensive to transport, perishable and may require refrigeration. Many medications and materials are or will be available in

    SBIR Phase II 2020 Department of DefenseDefense Health Agency
  2. Development of an ALDH2-Targeting RNAi Therapeutic for Alcohol Use Disorders

    SBC: Dicerna Pharmaceuticals, Inc.            Topic: 150

    Abstract Alcohol Use Disorder (AUD) is a chronic condition characterized by compulsive alcohol use, loss of control over alcohol use, and a negative emotional state when not using alcohol, with such use associated with a range of medical, psychological, social, economic, and personal problems. AUD is global and prevalent; in a survey of over 36,000 adults in the US, AUD had a 12-month prevalence o ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  3. The Development of a High Throughput Whole Brain Alzheimer's Disease Drug Screening Pipeline

    SBC: Tissuevision Inc            Topic: NIA

    Project Summary Alzheimer’s disease (AD) is a debilitating neurodegenerative disease affecting roughly 1 in 10 people over the age of 65. In 2017, the total cost of AD in the United States was estimated at $259 billion and is predicted to climb to $1.1 trillion by the year 2050. Despite enormous efforts invested in finding a cure, it has proven extremely difficult to develop treatments for AD. C ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  4. UTI Reduction in Neurogenic Bladder.

    SBC: ICET, INC            Topic: NIDILRR

    This Phase II SBIR project builds upon previous research of two novel functional gel compositions for use with intermittent and indwelling catheters to establish the prototype design, dose of prototype units, and the urinary tract infection (UTI) pathogenic burden on ex-vivo models; and to evaluate pre-clinical safety. There is a high incidence of life-long recurrent UTIs in individuals with neuro ...

    SBIR Phase II 2020 Department of Health and Human ServicesAdministration for Community Living
  5. High-Energy, Light-Weight Battery to Power Next Generation Wearable Assist Prosthetics.

    SBC: GINER INC            Topic: NIDILRR

    This Phase II SBIR project builds upon previous research to develop an increased life cycle, high-energy, lightweight, cost-efficient 1 Ah prototype battery designed specifically to support the next generation of powered prosthetic devices. Currently, prosthetic power supplies are not specifically designed for these applications and present a major hurdle for prosthetic design engineers. The Giner ...

    SBIR Phase II 2020 Department of Health and Human ServicesAdministration for Community Living
  6. Development of a Non Toxic Paint Stripper

    SBC: TDA RESEARCH, INC.            Topic: 19NCERP2

    There is a tremendous need for an all-purpose paint stripper that is safe to handle and that does not harm the environment. The most popular all-purpose paint strippers are based on methylene chloride (MeCl), which is dangerous to workers and harmful to the environment. In particular, it is highly volatile, and if it is used in an area with poor ventilation it is an immediate health hazard. In ext ...

    SBIR Phase II 2020 Environmental Protection Agency
  7. Low cost hyperspectral measurement system to identify harmful materials in construction and demolition (C&D) materials

    SBC: SYMBIOS TECHNOLOGIES INC.            Topic: 19NCERP2

    Because C&D materials constitute a significant waste stream, increasing the diversion of C&D materials, through recycling and reuse, is identified as an area of need in EPA’s Sustainable Materials Management (SMM) Program Strategic Plan. Due to a lack of technologies to quickly identify harmful constituents, C&D-materials recyclers often dispose of potentially usable materials as a matter of pre ...

    SBIR Phase II 2020 Environmental Protection Agency
  8. Quantitative Methane Plume Imager for Localization and Flow Rate Estimation in Mines

    SBC: PHYSICAL SCIENCES INC.            Topic: NIOSH

    ABSTRACT: NIOSH conducts activities to assure safe and healthful conditions for American workers. This proposed project addresses a NIOSH mission objective for innovative solutions that provide practical methods to identify and measure hazards at a reasonable cost in high-risk occupations (e.g. mining). The mining industry presents particularly challenging safety and health needs. Despite well-reg ...

    SBIR Phase II 2020 Department of Health and Human ServicesCenters for Disease Control and Prevention
  9. Improved Amputee Quality of Life Enabled by Tailored, Self-Regenerating Energy Storage Device For Powered Prosthetics

    SBC: GINER INC            Topic: NICHD

    Powered, motorized prosthetics enable users to more naturally perform tasks, such as climbing stairs or rising from a seated position. However because the power requirements fluctuate during the gait cycle; the current battery system is not energy efficient and also since energy is dissipated through a shunt resistor when the motor slows and changes direction. As a result the battery is (over)desi ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  10. Therapy and Prophylaxis for Genital Tract Infection

    SBC: THERAPYX, INC.            Topic: NIAID

    PROJECT SUMMARY/ABSTRACT Genital tract infection with Neisseria gonorrhoeae does not induce a state of specific protective immunity and can be acquired repeatedly. Despite public health measures, the disease persists at an unacceptably high frequency; there is no vaccine against it, and resistance even to the latest generations of antibiotics continues to emerge. TherapyX, Inc. is advancing GneX12 ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
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