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DESCRIPTION provided by applicant A research plan is proposed to produce potent human polyclonal antibodies against influenza viruses by immunizing genetically modified bovines with seasonal influenza vaccine in combination with a strong adjuvant and immune stimulator Previous studies have demonstrated that genetically engineered bovines are capable of producing large amounts of human polyclo ...

Currently available anti-thymocyte globulin (ATG) products are polyclonal animal antibodies (ATGAM – equine polyclonal ATG, Thymoglobulin – rabbit polyclonal ATG) and have found broad use as immune tolerizing agents, particularly for induction therapy in a majority of tissue transplants, for acute transplant rejection, and as treatment for graft vs. host disease following bone marrow transplan ...

Deep learning offers a powerful and extensible toolset to achieve or perhaps even exceed human-level accuracy for automatic object detection in stream of commerce data, and offers a path toward improving the effectiveness of scanners, reducing wait times, and radically increasing the accuracy of screening, where automatic object detection support is essential. A deep learning-based system for auto ...

The Synthetik team is uniquely placed to conduct this Phase II SBIR effort where we plan to extend and optimize our DeepSpektra high-resolution hyperspectral and deep learning-based non-contact detection technology to provide enhanced, targeted sampling for explosive and illegal drugs trace detection that was successfully demonstrated in Phase I.Synthetik's DeepSpektra technology directly addresse ...

Assisted Living Facilities (ALF) are the fastest growing means of providing assistance to the elderly with Alzheimer?s I Dementia (AD), but generally care is provided by untrained, nonprofessional staff. Therefore, the overall, long term goal of our program is to improve the quality of AD care for persons residing in assisted living facilities. In Phase I, the objective of the project was to devel ...

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Wildlife are a reservoir of diseases affecting both humans and domestic animals. These wildlife reservoirs represent a potential threat to public health, serving as a continuous and difficult to eradicate source of infection for zoonotic diseases, but may also represent a significant economic threat to US agriculture. In particular, wild ruminants including white-tail deer may harbor vector-bo ...

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DESCRIPTION (provided by applicant): Creature Control: Food for Thought is a health science curriculum supplement and obesity prevention unit tailored to be effective with American Indian (AI) students. It considers the AI experience as its frame of refere nce and much of the visual representation is inspired by American Indian culture. In Phase I, prototype games and a set of lesson plans were de ...