Award Data

THE OBJECTIVE OF THIS PROJECT IS TO (1) PROCESS LARGE NUMBERS OF CLONES THROUGH COLONY PICKING, (2) REPOSITION THECOLONIES IN LARGE RECTANGULAR ARRAYS, (3) PURIFY COLONIES BYRECLONING AS NECESSARY, (4) PROCESS THE DNA FROM EACH COLONYTO ALLOW RECOMBINANT DNAS TO BE TRANSFERRED TO NITROCELLULOSE OR OTHER FILTER MATERIALS, (5) PROBE THE ARRAYS EN MASSE WITH DNA PROBES UNDER DIFFERENT STRINGENCY COND ...

THIS PROJECT WILL ESTABLISH THE POTENTIAL FOR RAPID RESPONSE, HIGH RESOLUTION DETECTION AND CHARACTERIZATION OF INFRARED (IR) ACTIVE POLLUTANT MOLECULES, SUCH AS S02, N0, AND N02. MINIATURE OPTICAL HEAT PIPES WILL BE CONSTRUCTED AND OPTIMIZED FOR THE GENERATION OF TUNABLE IR LASER LIGHT BY MEANS OF STIMULATED ELECTRON RAMAN SCATTERING (SERS). THE HEAT PIPES WILL USE ALKALI METAL VAPORS AT PRESSURE ...

MAPPING AND SEQUENSING THE DNA IN THE HUMAN GENOME IS OF CRUCIAL IMPORTANCE TO FUTURE MEDICAL ADVANCES AND ECONOMIC COMPETITIVENESS. UTILIZATION OF DNA PROBES LABELED WITH DOZENS OF STABLE ISOTOPES INSTEAD OF A SINGLE RADIOISOTOPE COULD INCREASE THE RATE OF SEQUENCE DETERMINATION 100-FOLD OR MORE COMPARED TO CURRENT METHODS. THIS PROJECT INVOLVES A NEW APPROACH, LASER ATOMIZATION RESONANCE IONIZAT ...

DEMONSTRATION TESTING OF ADVANCED PROCESS EQUIPMENT IS EXPECTED TO CONFIRM THE FEASIBILITY OF THE INTEGRAL FAST REACTOR (IFR) FUEL CYCLE PROCESS AT THE HOT FUEL EXAMINATION FACILITY - SOUTH (HFEF-S) ON THE ARGONNE-WEST SITE IN IDAHO. TEST RESULTS WILL BE INCORPORATED INTO THE DESIGN OF A COMMERCIAL IFR FUEL CYCLE FACILITY. THIS PROJECT CONTRIBUTES TO DEVELOPMENT OF A CONCEPTUAL DESIGN FOR AN ADVAN ...

REMOTE MAINTENANCE OF THE COMPACT IGNITION TOKAMAK (CIT) POSES FORMIDABLE CHALLENGES BECAUSE OF ITS INTERNAL DIMENSIONAL CONSTRAINTS, DIVERSITY OF MAINTENANCE OPERATIONS, AND GEOMETRICALLY INTRICATE ARRANGEMENT OF EXTERNAL SERVICE EQUIPMENT. THESE CHALLENGES MUST BE ADDRESSED TO SUPPORT FUTURE "HOT" OPERATION OF THE PRINCETON PLASMA PHYSICS LABORATORY (PPPL) CIT. PHASE I INTRODUCES A SINGLE SOLUTI ...

THE TECHNICAL OBJECTIVES OF THIS PROPOSAL ARE ORIENTED TOWARD THE DEVELOPMENT OF SOIL SURFACTANT FLUSHING AND WASHING AS A LOW-COST, LOW-IMPACT, LOW-RISK, EFFECTIVE TECHNIQUE FOR THE REMOVAL AND ULTIMATE DESTRUCTION OF THE ORGANIC CONTAMINANTS IN SOIL. THESE OBJECTIVES ARE: DEMONSTRATION OF THE EFFECTIVENESS OF AN IONIC SURFACTANT SOLUTION AT CONCENTRATIONS ABOVE THE CRITICAL MICELLE CONCENTRATION ...

A THREE-DIMENSIONAL QUANTITATIVE DIELECTRIC IMAGING TECHNIQUE IS PROPOSED FOR MEASUREMENT OF VOID FRACTION, INTERFACIAL AREA, AND FLOW TOPOLOGY OF LIQUID TWO-PHASE FLOWS. WITH MICROWAVES AS PROBING RADIATION, IT MEASURES THE SCATTERING FIELDS USING AN ARRAY AND, THROUGH AN INVERSE SCATTERING PROCESS, RECONSTRUCTS THE DIELECTRIC PERMITTIVITY, BOTH REAL AND IMAGINARY PARTS, OF EVERY PIXEL OF THE FLO ...

THIS PROJECT WILL RESULT IN THE DEVELOPMENT OF A NEW TECHNOLOGY FOR MEASURING THE QUANTITY AND LOCATION, WITH SUBMICRON RESOLUTION, OF BORON IN BIOLOGICAL CELLS IN SUPPORT OF THE BORON NEUTRON CAPTURE THERAPY (BNCT) PROGRAM. THIS PROJECT THUS ADDRESSES THE MAJOR UNSOLVED TECHNICAL ISSUE IMPACTING BNCT CLINICAL EFFICACY. BNCT IS APROMISING RADIATION THERAPY IN WHICH NEUTRONS ARE USED TO ACTIVATE BO ...

THE MTIC INDIRECT STEAM REFORMING PROCESS OFFERS A COST EFFECTIVE ALTERNATIVE TO THE EXISTING WASTE-TO-ENERGY INCINERATION OF MUNICIPAL SLUDGE WASTE (MSW) OR REFUSE- DERIVED FUEL (RDF). THE PROCESS HAS THE POTENTIAL FOR RESOLVING MANY OF THE ENVIRONMENTAL ISSUES ASSOCIATED WITH INCINERATION, ESPECIALLY IN THE CONTROL OF CHLORINATED DIOXINS AND FURANS AS WELL AS EMISSIONS OF TOXIC METALS; PARTICULA ...

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