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The Award database is continually updated throughout the year. As a result, data for FY21 is not expected to be complete until September, 2022.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. A Versatile Microbot Fabrication Platform

    SBC: AMT Nano, LLC            Topic: 9050768R

    AMT Nano, LLC has developed innovative technology for achieving a versatile microrobot platform. The innovation relies on a unique micromolding process, which is low-cost and high-throughput, and high precison. The process achieves versatility by generating deterministic freeform shapes in polymers and nanocomposites. Several perceived benefits accompany the micromolding process. Due to the three- ...

    SBIR Phase I 2011 Department of CommerceNational Institute of Standards and Technology
  2. FEMOVAL OF GASOLINE FROM WATE SUPPLIES

    SBC: Lowry Engineering Inc.            Topic: N/A

    THE FEASIBILITY OF AMULTI-STAGED DIFFUSED AERATION TREATMENTSYSTEM FOR GASOLINE REMOVAL FROM CONTAMINATED HOUSEHOLD GROUND WATER SUPPLIES WILL BE STUDIED. EXPERIMENTS IN THE LABORATORY AND FIELD WILL IDENTIFY THE CONTROLLING GASOLINE COMPONENT COMPOUNDS FOR THE SYSTEM. THESE ADDITIVES ARE LIKELY TO INCLUDE METHYL TERTIARY BUTYL ETHER (MTBE) AND OTHER HIGHLY SOLUBLE AND POORLY ADSORBED COMPOUNDS. E ...

    SBIR Phase I 1986 Environmental Protection Agency
  3. A transfollicular nanovaccine against leishmaniasis

    SBC: VINDICO NANOBIOTECHNOLOGY, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): The World Health Organization estimates that over 350 million people are at risk of developing leishmaniasis and infection prevalence is 14 million people in the world. Annually, 2 million people are infected with Leishmania species and 270,000 will die. Leishmaniasis is one of the most important parasitic diseases affecting the U.S. military today, with over 2 ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  4. Apparatus and Method for Convection Enhanced Therapeutic Delivery

    SBC: FHC, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): Malignancies of the brain are among the most devastating diseases known. Glioblastoma multiform (GBM) in particular are known for their rapid, uncontrolled, and aggressive growth. Very little progress has been made in the treatment of GBM over the past 25 years. A more recent promising therapeutic approach is convection enhanced delivery (CED) in which chemothe ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  5. Modulation of In Vivo Tumor Oxygenation via Polymersome-encapsulated Myoglobin

    SBC: VINDICO NANOBIOTECHNOLOGY, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): Over 250,000 new cases of head and neck cancers (HNCs) and non-small cell lung cancers (NSCLCs) are diagnosed every year in the United States. At the time of diagnosis, 60% of these cases are regionally advanced (stageIII and IV). Wide surgical excision is not the immediate therapeutic option for most of these locally advanced solid tumor malignancies. A number ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  6. Transdermal Cannabidiol Prodrug Delivery

    SBC: ALLTRANZ, INC.            Topic: NIDA

    DESCRIPTION (provided by applicant): With over 8.5% of the U.S. population and 75 million people worldwide meeting the diagnostic criteria for alcohol use disorders (AUDs), alcohol abuse is among the top three preventable public health problems in the U.S.and the world. AUDs, commonly referred to as alcoholism, have a complex etiology where chronic alcohol associated neurodegeneration, withdrawal- ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  7. Use of a viral mucin-like protein to convert adherent cells to suspension culture

    SBC: PARATECHS CORP.            Topic: NIGMS

    DESCRIPTION (provided by applicant): Most cell culture lines are anchorage-dependent and require surface attachment for proliferation. For industrial production, increased surface area can be provided by microcarrier beads, but the associated increases incost and the resulting complexity of manipulation may preclude their use. Due to these limitations, anchorage-independent cells are preferred for ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  8. Novel method to create knockout rats using endonucleases and spermatagonialstem

    SBC: TRANSPOSAGEN BIOPHARMACEUTICALS, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): The laboratory rat is the preferred rodent model in pre-clinical drug studies and encompasses the bulk of accumulated knowledge in drug development. Their larger size facilitates procedures otherwise difficult in mice,including studies using instrumentation, blood sampling, and surgeries. Although rats are more suitable than mice for pharmacological, toxicologi ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  9. Sleep Apnea Diagnostic

    SBC: TELEHEALTH HOLDINGS, LLC            Topic: NHLBI

    DESCRIPTION (provided by applicant): Sleep apnea is a common respiratory disorder during sleep, which has significant individual, healthcare system, and societal impact. The current gold standard method for sleep apnea assessment is full night polysomnography (PSG). However, its high cost, inconvenience, long waiting lines, and immobility have persuaded researchers to seek simple and portable devi ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  10. Beyond Pillboxes: Medminding for Universal Drug Delivery

    SBC: TELEHEALTH HOLDINGS, LLC            Topic: NINR

    DESCRIPTION (provided by applicant): Medication errors are now the leading cause of accidental death. Smart electronic devices are emerging to aid medication adherence with organizing, reminding, monitoring, and communicating medication use. Most are focused on bulk pills and are structured to dispense pills, remind at pill-time, monitor when pills are taken, or communicate pill histories to care ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
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