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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Novel Absorbent for Efficient Enantiomer Separation

    SBC: BEND RESEARCH, INC.            Topic: N/A

    Chiral drugs, when administered in enathiomerically pure form, offer significant clinicaladvantages over their racemic counterparts. However, available methods for chiral resolution of racemiccompounds, such as diasteriomeric derivatization and chiral chromatography, have drawbacks, includinghigh cost, difficulty with scale-up and lack of applicability for many chiral compounds. This project isdir ...

    SBIR Phase I 1994 Department of Health and Human Services
  2. Enzyme Triggered Membranes for Colonic Drug Delivery

    SBC: BEND RESEARCH, INC.            Topic: N/A

    N/A

    SBIR Phase I 1994 Department of Health and Human Services
  3. Choice Card: A Model for Health Plan Selection

    SBC: Benova            Topic: N/A

    N/A

    SBIR Phase I 1994 Department of Health and Human Services
  4. Development of Accurate Test Kits for Malabsorption

    SBC: BIOCHEMANALYSIS CORPORATION            Topic: N/A

    Accurate measurement of gastrointestinal absorption of various substances is important in bothresearch and diagnosis. In many cases, the acceptable general approach is the balance procedure. Thisprocedure suffers from the requirement for complete collection of stools over an extended period oftime. This limitation prevents widespread use of this otherwise desirable approach. The investigatorspropo ...

    SBIR Phase I 1994 Department of Health and Human Services
  5. Micron Resolution Volume-Computed Tomography

    SBC: BIO-IMAGING RESEARCH, INC.            Topic: N/A

    Instrumentation that can provide microstructural characterization of medical grade polymers,fabrics, and composite materials is the proposed research's long term goal. One micron resolutionvolume computed tomography of test specimens can now be demonstrated by combining anNIST-developed x-ray microscope with BIR's volume CT capability. Micro VCT will be a valuable toolin the development of new med ...

    SBIR Phase I 1994 Department of Health and Human Services
  6. Fiber Optic Sensor for Cardiac Magnetic Field

    SBC: BIO-IMAGING RESEARCH, INC.            Topic: N/A

    We will adapt a non-cryogenic magnetic field sensor previously developed for defense purposesand apply it to magnetocardiography (MCG), the measurement of magnetic fields induced by electricalcurrents in the heart. As a single non-invasive sensor, this unit would have similar applications to theelectrocardiograph. When these units are assembled into a spatial array, the magnetic field can bemeasur ...

    SBIR Phase I 1994 Department of Health and Human Services
  7. Reality Based Multisystem Balance Assessment in the Aged

    SBC: Brookside Research & Development            Topic: N/A

    N/A

    SBIR Phase I 1994 Department of Health and Human Services
  8. Novel Compounds for the Treatment of Memory Disorders

    SBC: Chicago Institute For Neuro            Topic: N/A

    We have generated a monoclonal antibody, B6B21, and have shown that it significantlyenhances acquisition rates in hippocampus-dependent trace eyeblink conditioning in rabbits, halving thenumber of trials required to reach 80% conditioned responses. Previous studies, with a variety of modelsystems, have shown that B6B21 acts as a partial ago mst at the glycine site of the N-methyl-D-aspart-ate rece ...

    SBIR Phase I 1994 Department of Health and Human Services
  9. Interactive Physiology Simulator for Teaching Medicine

    SBC: Critical Concepts, Inc.            Topic: N/A

    We will develop a computer simulation of the critically ill patient for use in training medical students, residents, nurses, fellows, and physicians. This computer software will faithfully simulate the functional aspects of cardiopulmonary physiology, using state-of-the-art mathematical models. For the first time, students at all levels will have the freedom to learn medical physiology and therape ...

    SBIR Phase II 1994 Department of Health and Human Services
  10. Interactive Media for Early Detection of Skin Cancers

    SBC: EDUMEDIA, INC.            Topic: N/A

    Elderly women and men are at higher risk for developing skin cancers, as a result of theirincreased cumulative exposure to ultraviolet radiation, and their depressed immune system functioningrelative to younger persons. Interactive multimedia materials providing information about skin lesionsand teaching early detection skills will be developed for target groups of elderly. Social cognitiveprincip ...

    SBIR Phase I 1994 Department of Health and Human Services

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