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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Digoxin Chiral Isolates as Improved Pharmaceuticals

    SBC: ACADEMIC PHARMACEUTICALS            Topic: N/A

    DESCRIPTION (provided by applicant): Digoxin is the first line pharmacologic therapy for CHF and AF. Digoxin increases cardiac contractility and blocks conduction through the AV node slowing the ventricular response to AF and thus slowing the rate of the beating ventricles permitting more time for the heart to fill. The recent Dig trial supports the use of digoxin in the treatment of CHF and the r ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  2. Nanoadsorbent and Microwave Technology to Capture and Recover Organic Vapors

    SBC: ADS Technoogies, Inc.            Topic: N/A

    Emissions of volatile organic compounds (VOCs) and hazardous air polutants (HAPS are a serioud environmental issue. These pollutants are requlated to protect human health and encourage the development of better control technologies. Current technologies to control thses emissions, until better materials are developed, include destructive and/or recovery-based technologies. Implementation of ads ...

    SBIR Phase I 2005 Environmental Protection Agency
  3. Vascular Permeability Normalization in Ischemic Stroke

    SBC: Advanced Life Sciences, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Stroke is the third leading cause of death in the United States and is the number one cause of adult disability. It is estimated that this clinical condition results in a cost of $30-40 billion in the U.S alone. While a large number of therapeutic agents have been investigated for the treatment of ischemic stroke, only one agent is currently approved for marke ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  4. Gene Expression and Diagnosis of Diabetes

    SBC: ARTHROCHIP, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Autoimmune diseases are difficult to diagnose, as the symptoms can be nonspecific. A single test that could readily distinguish between an autoimmune and non-autoimmune disorder would allow physicians to focus efforts on the specific disease that affects the patient. This is critical for diabetes mellitus (DM), which has two subsets, Type I and Type II. The sub ...

    STTR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  5. Development of Structural Building Elements from Oriented Straw Cable

    SBC: Ashland Prototypes            Topic: N/A

    The overall goal of this proposed project is the development of load bearing, structural building elements from oriented straw. Producting building elements from surplus staw will help provide low-cost housing in rural areas, and will help reduce greenhouse emissions associated with the production of typical construction materials. Producting building materials free from VOCs and other toxins wi ...

    SBIR Phase I 2005 Environmental Protection Agency
  6. Genosensor Matrices for Genome Mapping and Sequencing

    SBC: ATOM SCIENCES, INC.            Topic: N/A

    This project will use sequencing by hybridization (SBH) to develop a faster, more economicalmethod for sequencing and mapping. Current DNA sequencing procedures almost universally require gelelectrophoresis of DNA fragments and are cumbersome and slow. SBH promises to produce rapidly largeamounts of sequence information due to the parallel nature of the analysis and is well suited forsequencing cD ...

    SBIR Phase I 1994 Department of Health and Human Services
  7. Specific Diagnostic for Members of Genus Mycobacterium

    SBC: ATOM SCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): A novel microarray-based system is proposed for diagnosis of tuberculosis and tuberculosis-like respiratory infections. This diagnostic system offers a parallel method to screen clinical samples for the presence of DNA sequences from Mycobacterium tuberculosis, the causative agent of human tuberculosis, and closely related mycobacterial species, while simultan ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  8. Optimizing Electrophoresis Gels for Rimp Analysis

    SBC: ATOM SCIENCES, INC.            Topic: N/A

    N/A

    SBIR Phase I 1994 Department of Health and Human Services
  9. Apoptotic Regulation of Lymphocyte Responses

    SBC: Avi Biopharma, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The response of lymphocytes to antigen stimulation is characterized by proliferation of an antigen-sensitive lymphocyte population, subsequent differentiation to subsets with effector cell function, and ultimately the retention of antigen-responsive lymphocytes with a memory cell phenotype. The initial increase of responsive lymphocytes is followed by an equall ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  10. Antisense Antiviral Agent for West Nile Infections

    SBC: Avi Biopharma, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): AVI BioPharma has been developing an antisense phosphorodiamidate morpholino oligomer, AVI-4020 for the treatment of West Nile Virus. AVI-4020 has been shown both to reduce viral titer, and to cross the blood brain barrier. This compound targets the translation start site of the single open reading frame of WNV. Studies to date indicate AVI-4020 is a reasonabl ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
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