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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Soluble high-affinity T cell receptors prevent MRSA lethality

    SBC: IMMUVEN, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): Methicillin resistant Staphylococcus aureus (MRSA) and methicillin sensitive S. aureus (MSSA) are highly significant human health threats that are responsible for a range of diseases. Recently, the CDC and colleagues reported that MRSA are the most significant causes of serious infections and infectious disease deaths in the United States. A major factor involv ...

    SBIR Phase II 2012 Department of Health and Human Services
  2. Therapeutic factor XI blockade for sepsis

    SBC: Aronora, Inc            Topic: NIAID

    DESCRIPTION (provided by applicant): This SBIR Phase II grant will support the commercial development of an injectable biological product candidate, a unique proprietary recombinant humanized anti-factor XI monoclonal antibody (AXIMAB), towards an investigational new drug (IND) application. The lead indication for AXIMAB is severe bacterial sepsis, which is a major cause of mortality in hospitaliz ...

    SBIR Phase II 2012 Department of Health and Human Services
  3. Non-invasive Assessment of Skeletal Muscle Loss in Cancer Patients


    DESCRIPTION (provided by applicant): Abstract The long-term objective of this research is to develop a non-invasive approach for assessment of de novo 3MH production in cancer patients early in the course of the disease as a way of assessing which patients are at high risk for future development of skeletal muscle atrophy. The approach is based on: 1) the known increase in de novo production ...

    SBIR Phase II 2012 Department of Health and Human Services
  4. Cross-platform remote monitoring technologies to monitor and improve adherence to


    DESCRIPTION (provided by applicant): Medication nonadherence is a costly healthcare problem, adding 177 billion annually to the nation's healthcare expenditures. Three out of four Americans do not take their medicine as prescribed, and the ramifications affect virtually every aspect of the health care system. It is called America's other drug problem for good reason. Nonadherence issues ...

    SBIR Phase II 2012 Department of Health and Human Services
  5. Online Training for Resource Parents of Substance-Exposed Children

    SBC: NORTHWEST MEDIA, INC            Topic: NIDA

    DESCRIPTION (provided by applicant): While foster-adoptive parents receive some rudimentary training just prior to or in the early months following adoption finalization, many stil harbor unrealistic expectations about adoption and are unaware of the severe behavioral problems they may encounter, no less the role that exposure to substance abuse may play in the child's development. Our Phase ...

    SBIR Phase II 2012 Department of Health and Human Services

    SBC: Health Education Research Systems, llc            Topic: NIDA

    DESCRIPTION (provided by applicant): (Phase-2, Renewal) The SACC-Substance Addiction Collaboration Channel(R) platform is a new Collaboration, WEB-2.0 springboard specifically designed to structure and share information across the Behavioral/Mental Health Workforce community with the special focus on Substance-Addiction Disorders. SACC is an individual and group-level application platform th ...

    SBIR Phase II 2012 Department of Health and Human Services

    SBC: DAHL NATURAL L.L.C.            Topic: NIEHS

    DESCRIPTION (provided by applicant): Development of a phase 2 beta for demonstration in Tree Top juice processing plant of a Field Applicable Real-time Remote Monitoring Sensor Device capable of detecting multiple pesticides simultaneously in unfiltered juice, fluid or waste water. We propose to further develop the carbon nanotube matrices active biosensor area for effective immobilization of mult ...

    SBIR Phase II 2012 Department of Health and Human Services
  8. Embosser Using Polymer Roller for Production of Improved Braille and Tactile Grap


    DESCRIPTION (provided by applicant): The specific aim of this proposal is to develop and implement a new type of technology for production of braille and tactile graphics that uses a system in which metal punch pins fire into a smooth polymer-coated shaftrather than into a machined metal die as with most current embossing technologies. The successful completion of this project will yield a new bra ...

    SBIR Phase II 2012 Department of Health and Human Services
  9. Factor XI inhibitor for thrombosis

    SBC: Aronora, Inc            Topic: NHLBI

    DESCRIPTION (provided by applicant): Thrombotic cardiovascular diseases including venous thromboembolism (VTE), deep vein thrombosis (DVT), myocardial infarction, and ischemic stroke, remain leading causes of death and disability in the U.S. Although effective antithrombotic agents are available, these drugs inadvertently target vital hemostatic molecular mechanisms and can produce severe dose-lim ...

    SBIR Phase II 2012 Department of Health and Human Services
  10. Mission Reconnect: Promoting Resilience and Reintegration of Post-Deployment Vete

    SBC: Collinge And Associates, Inc.            Topic: NIMH

    DESCRIPTION (provided by applicant): There is an urgent and growing need for mental health interventions supporting both short- and long-term reintegration of veterans of OIF and OEF into their communities and significant relationships. Innovative approaches are needed to support the well-being of veterans who may not access or be reached by formal services. Objectives. This Phase II project will ...

    SBIR Phase II 2012 Department of Health and Human Services

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