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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. High-potency nitro antimicrobials for topical treatment of trichomoniasis

    SBC: DESIGNMEDIX, INC.            Topic: R

    DESCRIPTION provided by applicant Trichomonas vaginalis is the causative agent of the most common non viral sexually transmitted infection with million new cases reported annually in the world and million cases in the U S In addition to infections of the urogenital tract trichomoniasis increases the risk of adverse pregnancy outcomes and HIV transmission and increases the incidence ...

    STTR Phase I 2016 Department of Health and Human Services
  2. Aminopiperidines as novel anti influenza agents

    SBC: Chicago Biosolutions, Inc.            Topic: NIAID

    Influenza A viruses belong to the orthomyxoviridae family with a negative sense segmented RNA genome which can cause seasonal or pandemic flu with high morbidity and significant mortality Vaccination is the most prevalent prophylactic means for controlling influenza infections However an effective vaccine usually takes at least months to develop for the circulating strains Furthermore vac ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Monochromatic 222 nm UV light: Development of a safe, cost-effective technology for the efficient reduction of bacterial and viral infection and transmission

    SBC: EDEN PARK ILLUMINATION, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Drug resistant bacteria such as MRSA and airborne transmitted microbes such as influenza and TB together present major health issues both in the developed and the developing world with major health care and economic consequences Recent research from Columbia University Medical Center demonstrated that single wavelength far UVC photons can kill bacteria a ...

    STTR Phase I 2016 Department of Health and Human Services
  4. A chimeric protein for the selective expansion of regulatory T cells

    SBC: Sahane Biotech, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant Type diabetes T D is a chronic disease caused by the autoimmune destruction of the insulin producing beta cells in the pancreas Current treatment options for T D are severely limited All patients diagnosed with T DM are placed on life long insulin therapy and the current standard of care for adult patients with T DM is intensive diabetes therapy to avoid ...

    STTR Phase I 2016 Department of Health and Human Services
  5. Development of DRα1-MOG-35-55 for treatment of DR2 negative MS subjects

    SBC: Virogenomics BioDevelopment Inc            Topic: NIAID

    DESCRIPTION provided by applicant Our laboratory discovered and is developing partial p MHC class II constructs pMHC as a possible immunotherapy for multiple sclerosis MS pMHC containing the extracellular domains of the MS risk factor HLA DR linked covalently to the encephalitogenic peptide of myelin oligodendrocyte glycoprotein pDR MOG can reverse CNS inflammation and ...

    STTR Phase I 2016 Department of Health and Human Services
  6. Developing a method to increase HIV testing among YMSM

    SBC: RESILIENT GAMES STUDIO, LLC            Topic: NICHD

    DESCRIPTION provided by applicant Adolescents are particularly vulnerable to HIV and account for one quarter of all new infections each year Most new infections among adolescents occur among young men who have sex with men YMSM Transmission of HIV can be virtually eliminated by treatment but testing rates are low and a significant proportion of YMSM are unaware of their HIV status P ...

    STTR Phase I 2016 Department of Health and Human Services
  7. NMDA RECEPTOR MODULATORS AS NOOTROPIC THERAPIES IN AGING BRAIN

    SBC: Aptinyx Inc            Topic: NIA

    DESCRIPTION provided by applicant Age related memory loss is a growing public health issue which will be magnified in the coming decades by increasing life expectancies and the aging baby boomer population Age is the most important risk factor for developing dementia of the population between and has some form of dementia between and and of those or older The the ...

    SBIR Phase I 2016 Department of Health and Human Services
  8. An Ultra filtrate perfusion bio artificial pancreas for high-density islet replacement without immunosuppression

    SBC: Norfolk Medical Products, INC.            Topic: NIDDK

    DESCRIPTION provided by applicant The Cell SafeTM is a fundamentally new approach in replacement of dysfunctional insulin producing cells in patients with diabetes by transplantation of new islets in a three dimensional scaffold embedded in a highly compatible bioengineered perfusion system that continuously supplies tissue fluid blood ultrafiltrate so that the cells ae protected from immun ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Screening for pancreatic cancer via nanocytology of duodenal cells

    SBC: NANOCYTOMICS LLC            Topic: NCI

    DESCRIPTIONprovided by applicantThe goal of this SBIR project is to develop a minimally intrusivehighly sensitive risk stratification tool to determine the need for invasive pancreatic cancerPCscreeningPC is theth leading cause of cancer deaths in the USWhile early stage disease is generally curablethe vast majority of patients are diagnosed in advancedunresectable stages due in large part to the ...

    SBIR Phase I 2016 Department of Health and Human Services
  10. A Holographic Waveguide Display Based Low Vision Eyewear

    SBC: Biolight Engineering LLC            Topic: N

    DESCRIPTION provided by applicant Low vision rehabilitation is the only proven way to restore functional vision and maintain a high quality of life in patients with permanent vision impairment Low vision aids are devices that manipulate visual information for example magnify images to compensate for impaired vision The patientandapos s willingness to accept a low vision aid ability to ada ...

    SBIR Phase I 2016 Department of Health and Human Services
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