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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. TOPIC 384: CANCERCOSTDETOX: DETOXING CANCER CARE FINANCIAL TOXICITY

    SBC: BRIGHTOUTCOME INC.            Topic: NCI

    The prohibitive cost of cancer care has been widely describedCancer treatment received by patients with insurance can still result in a considerable financial burdenNon adherence is one of the best studied outcomes resulting from higher care costsFinancial distress has also been linked to changes in treatment related decision makingincluding the decision against a treatment course because of costA ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Development of digital and interactive methods to teach immunology

    SBC: FLUID CONTENT INC            Topic: NIGMS

    Abstract The goal of this project is to develop a digital media based program to teach high school student about immunologyWe will develop an interactive digital media to teach minority studentshigh schoolon the introduction of immunology and compare the efficacy of learning between traditional teaching and interactive mediaWe will develop three curriculums to teach group of high school students r ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Noninvasive Home Assessment of Cardiac Filling Pressure to Identify Heart Failure Patients at High Risk for Readmission

    SBC: Vixiar Medical, Inc            Topic: NHLBI

    Congestive heart failureCHFis the most common reason for hospitalization in the U Swith overmillion admissions per yearPatients admitted with CHF usually need IV diuretics to promote fluid removalThe readmission rate is highoverbydaysandbydays post dischargeThis also presents an enormous economic burdenhospitalizations account for a large percentage of the $billion spent yearly on heart failureOne ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Device to Measure Pain using Facial Expression Recognition Integrated with Patient PAINReportIt Tablet

    SBC: ENURSING LLC            Topic: NIDA

    Abstract Our goal is to develop a product that will objectively measure pain using computer vision and machine learning technologies together with tablet based self reported pain data from patients for research or clinical purposesOur device will be low cost because it will consist of one or two cameras to record the video and a computer to analyze the video in almost real timeThe software of the ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Amorphous Pharmaceutical Product Development Using Containerless Methods

    SBC: Materials Development, Inc.            Topic: 300

    Amorphous Pharmaceutical Product Development Using Containerless Methods Project Summary The overall objective of this research is to advance drug discovery through preciseengineeringof the structure and properties of API bearing phasesMany emerging drugs cannot be used in their naturally insoluble crystalline forms or they require crystallization in a preferred polymorph in order to be activeIn s ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Targeted Small Molecular Mertansine Delivery for Triple Negative Breast Cancer Treatment

    SBC: Iria Pharma, LLC            Topic: 102

    Project Summary Triple negative breast cancerTNBCis a subtype of breast cancerthat occurs in aboutof diagnosed breast cancerswhich is more likely to affect younger peopleAfrican AmericansHispanicsand or those with BRCAgene mutationThe projected TNBC annually diagnosed cases in United States are estimated to be more thanbyDue to the lack of the identified receptors on tumor cell surfaceTNBC patient ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Development of a High-Throughput Magnetic Cytometer for Single Cell Sorting

    SBC: Microsensor Labs, LLC            Topic: 400

    Project Summary This Small Business Innovation Research Phaseproject will develop a novel magnetic cytometer to rapidly isolateidentify and sort single intact and viable cells from heterogeneous cell population for single cell analysisSingle cell analysis is the key to investigate fundamental biological principles behind cell heterogeneity and disease evolutionSorting of single cells from heteroge ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Development and evaluation of a polymer coated proprietary cream formulation of resiniferatoxin nanoparticles for the treatment of pain associated with Diabetic Peripheral Neuropathy

    SBC: Premkumar, Louis            Topic: 200

    Development and Evaluation of a polymer coated proprietary cream formulation ofresiniferatoxin nanoparticles for the Treatment of Pain Associated with DiabeticPeripheral Neuropathy Diabetes is a major problem in developed and developing countriesIt is estimated thatmillion adults will have diabetes globally by yearOne of the major complications of diabetes is diabetic peripheral neuropathyDPNresul ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Plug-and-Play Microsystem Enabling Highly Sensitive Analysis of Volatile Organic Compounds

    SBC: ZEBRA ANALYTIX, INC.            Topic: NIEHS

    Project SummaryThis SBIR Phase I project will investigate the technical feasibility of a microfabricated chip system for enabling on site or in fieldhighly sensitive analysis of volatile organic compoundsVOCsin aqueous samplesThe system consists of two chips in a tandem configurationThe first chip is designed to extract VOCs directly from water samplesThe extracted VOCs are concentrated in the sec ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Nucleation Enhanced Crystallization of Pharmaceuticals in Continuous Flow Manufacturing to Mitigate Therapeutic Drug Shortages

    SBC: DENOVX, LLC            Topic: 100

    PROJECT SUMMARY DeNovX and its collaborators in the Myerson Group at MIT are developing innovative approaches to improve crystallization of active pharmaceutical ingredientsAPIsand proteinsThe goal of this Phase II grant is to expand the use of continuous flow crystallization using enhanced nucleation surfaces to the manufacture of small molecule therapeutics to improve efficiencieseconomicsand dr ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health

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