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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Digoxin Chiral Isolates as Improved Pharmaceuticals

    SBC: ACADEMIC PHARMACEUTICALS INC            Topic: N/A

    DESCRIPTION (provided by applicant): Digoxin is the first line pharmacologic therapy for CHF and AF. Digoxin increases cardiac contractility and blocks conduction through the AV node slowing the ventricular response to AF and thus slowing the rate of the beating ventricles permitting more time for the heart to fill. The recent Dig trial supports the use of digoxin in the treatment of CHF and the r ...

    SBIR Phase I 2005 Department of Health and Human Services
  2. Nanoadsorbent and Microwave Technology to Capture and Recover Organic Vapors

    SBC: ADS Technoogies, Inc.            Topic: N/A

    Emissions of volatile organic compounds (VOCs) and hazardous air polutants (HAPS are a serioud environmental issue. These pollutants are requlated to protect human health and encourage the development of better control technologies. Current technologies to control thses emissions, until better materials are developed, include destructive and/or recovery-based technologies. Implementation of ads ...

    SBIR Phase I 2005 Environmental Protection Agency
  3. Vascular Permeability Normalization in Ischemic Stroke

    SBC: Advanced Life Sciences, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Stroke is the third leading cause of death in the United States and is the number one cause of adult disability. It is estimated that this clinical condition results in a cost of $30-40 billion in the U.S alone. While a large number of therapeutic agents have been investigated for the treatment of ischemic stroke, only one agent is currently approved for marke ...

    SBIR Phase I 2005 Department of Health and Human Services
  4. High-performance Food Pathogen Detection Instrument

    SBC: Biodetection Instruments, Inc            Topic: N/A

    DESCRIPTION (provided by applicant): The primary objective of this Phase II project is to develop an innovative benchtop instrument for use on-site at food processing facilities with high performance, ease-of-use, and a low per sample cost for rapid, specific, and sensitive detection of multiple pathogens including Escherichia coli O157:H7, Listeria monocytogenes, and Salmonella Typhimurium in re ...

    SBIR Phase II 2005 Department of Health and Human Services
  5. Point Source Ozonation to Minimize Antibiotic Resistance

    SBC: Biodetection Instruments, Inc            Topic: N/A

    DESCRIPTION (provided by applicant): BluelnGreen, LLC proposes to develop an effective, versatile and cost efficient device for the application of ozone micro-bubbles to the effluent of critical point sources of medical wastewater (hospitals, large clinics and pharmaceutical manufacturing plants) to reduce the overall amount of both antibiotic residuals and resistant pathogens that are released t ...

    STTR Phase I 2005 Department of Health and Human Services
  6. Long-term Iron Needs of Renal Transplant Recipients

    SBC: BIOCHEMANALYSIS CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): The long-term objectives of this project are to: (a) Formulate an oral iron/ascorbic acid supplement specific to the needs of renal transplant recipients (RTxRs), (b) evaluate the efficacy of oral iron/ascorbic acid supplementation to meet the iron needs of this patient population as part of their routine post-transplant (post-Tx) care, and (c) establish a cons ...

    SBIR Phase I 2005 Department of Health and Human Services
  7. Non-invasive Assessment of Insulin Resistance

    SBC: BIOCHEMANALYSIS CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): The long-term objectives of this project are to develop a novel non-invasive test of insulin resistance. The proposed test is based on the well-established principle of inverse relationship between glucose oxidation (Gox) and lipid oxidation (Lox) during cellular respiration. Because the ratio of whole-body Gox/Lox can be measured precisely after administratio ...

    SBIR Phase I 2005 Department of Health and Human Services
  8. A Test of Iron Malabsorption in Patients with IDA

    SBC: BIOCHEMANALYSIS CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): Iron deficiency anemia (IDA) is a major problem among adults and elderly. In men and postmenopausal women, IDA is currently thought to result from gastrointestinal (GI) blood loss. Despite thorough GI tract evaluation, a significant number of patients are found to be negative for fecal occult blood (FOB) and >30% do not have lesions consistent with chronic bloo ...

    SBIR Phase I 2005 Department of Health and Human Services
  9. PROsIT: A Total Patient-Reported Outcomes Solution

    SBC: BRIGHTOUTCOME INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The PROsIT Project seeks to promote the use of patient-reported outcomes (PROs) for HIV-infected patients in clinical settings by developing and commercializing a comprehensive, practical and integrated system for PROs management with cross-discipline efforts. In Phase I, we successfully implemented and pilot-tested an IRT-based adaptive PROs assessment engin ...

    SBIR Phase II 2005 Department of Health and Human Services
  10. COMPREHENSIVE PRO MANAGEMENT FOR ONCOLOGY PRACTICE-SBIR TOPIC 212

    SBC: BRIGHTOUTCOME INC.            Topic: N/A

    N/A

    SBIR Phase I 2005 Department of Health and Human Services
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