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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. TECHNOLOGY FOR DETECTION OF SINGLE BASE MUTATIONS

    SBC: AMBION DIAGNOSTICS, INC.            Topic: N/A

    THE GOAL OF THIS PROJECT IS TO DEVELOP A RIBONUCLEASE PROTECTION/MISMATCH ASSAY, WHICH WILL ALLOW THE DETECTION OF ESSENTIALLY ALL SINGLE-BASE MUTATIONS. SUCH AN ASSAY WOULD PROVIDE AN INEXPENSIVE AND WIDELY APPLICABLE METHOD FOR SCREENING FOR GENETIC DISEASES, DETECTING MUTATIONS IN ONCOGENES AND TUMOR SUPRESSOR GENES, TYPING VIRUSES AND FOR OTHER RESEARCH AND DIAGNOSTIC APPLICATIONS. CURRENT RIB ...

    SBIR Phase II 1993 Department of Health and Human Services
  2. Development of High-Speed Nucleic Acid Hybridization

    SBC: AMBION DIAGNOSTICS, INC.            Topic: N/A

    N/A

    SBIR Phase I 1993 Department of Health and Human Services
  3. NEW BIOCOMPATIBLE DIALYSIS MEMBRANES

    SBC: ANATRACE, INC.            Topic: N/A

    END-STAGE RENAL FAILURE IS TREATED BY AN EXTRACORPOREAL DIALYSIS DEVICE. OVER 250,000 PATIENTS WORLDWIDE ARE MAINTAINED BY SUCH THRICE WEEKLY TREATMENTS. THE EVOLUTION OF THE MODERN DIALYZER HAS BEEN GREATLY DEPENDENT ON ADVANCES MADE IN POLYMERIC MATERIAL SCIENCE. WHILE THE MODERN DIALYSIS UNIT HAS REACHED A HIGH STATE OF SAFETY AND EFFICIENCY, THERE IS STILL ROOM FOR IMPROVEMENTS IN THE AREAS OF ...

    SBIR Phase II 1993 Department of Health and Human Services
  4. Production of Monoclonal Antibodies Specific to Vivrio Cholerae 01

    SBC: ANATRACE, INC.            Topic: N/A

    PRINCIPAL INVESTIGATOR: Chi, Kefung AWARDEE ORGANIZATION: BioKwitech, Inc. 4204-L Sorrento Valley Boulevard San Diego, CA 92121 TELEPHONE NUMBER: (619) 587-6738 AWARDEE NUMBER: 200-93-0667 Cholera is a very severe epidemic disease caused by cholera toxin (CT) of Vibrio cholerae (V. cholerae). Two major serotypes (Ogawa and Inaba) have been identified as defined by O antigens of lipopolysaccharide ...

    SBIR Phase I 1993 Department of Health and Human Services
  5. Production of Wild-Type Measles Hemagglutinin in hte Yeast

    SBC: ANATRACE, INC.            Topic: N/A

    PRINCIPAL INVESTIGATOR: Nakano, Eileen T. AWARDEE ORGANIZATION: Hawaii Biotechnology group, Inc. 99-193 Aiea Heights Dr. Aiea, HI 96701 TELEPHONE NUMBER: (808) 486-5333 AWARDEE NUMBER: 200-93-0668 The incidence of measles infections in North America has recently increased. Sequence comparison between new wild-type isolates and the vaccine strain (Moraten) show distinct genetic variation, which may ...

    SBIR Phase I 1993 Department of Health and Human Services
  6. The Development of Moleculary Pure Antibody Reagents to Variant

    SBC: ANATRACE, INC.            Topic: N/A

    PRINCIPAL INVESTIGATOR: Slack, John H. AWARDEE ORGANIZATION: Integrated Biotechnology Corp. 11711 North College Ave., Suite 196 Carmel, IN 46032 TELEPHONE NUMBER: (317) 575-7250 AWARDEE NUMBER: 200-93-0669 Measles virus, a severe acute highly contagious human pathogen, is not only responsible for clinical measles, but also for persistent central nervous system disease. In the United States, with t ...

    SBIR Phase I 1993 Department of Health and Human Services
  7. Porosity Prevention in Prophylactic Membranes

    SBC: ANATRACE, INC.            Topic: N/A

    Latex rubber articles in the form of condoms and gloves are used as barriers against the transmission of infectious diseases. The medical community have identified the use of condoms as an effective means for preventing the transmission of the human immunodeficiency virus (HIV) and other sexually transmitted diseases. Universal precaution procedures for health care workers requires wearing, and ch ...

    SBIR Phase I 1993 Department of Health and Human Services
  8. Flagellar Antigen Rapid Test for Detection of Antibodies to Borrelia

    SBC: ANATRACE, INC.            Topic: N/A

    PRINCIPAL INVESTIGATOR: Levin, Andrew E. AWARDEE ORGANIZATION: Immunetics 380 Green Street Cambridge, MA 02139 TELEPHONE NUMBER: (617) 492-5416 AWARDEE NUMBER: 200-93-0666 The research program is aimed at providing a simple and reliable serological test which can be used in clinical laboratories, physicians' offices and field stations as an aid in the rapid diagnosis of Lyme Disease. The test is b ...

    SBIR Phase I 1993 Department of Health and Human Services
  9. Development of Antipeptide Antibodies as Immunodiagnostic Probes

    SBC: ANATRACE, INC.            Topic: N/A

    PRINCIPAL INVESTIGATOR: Reynolds, Steven H. AWARDEE ORGANIZATION: Life Sciences, Inc. 2900 72nd Street, North St. Petersburg, FL 33710 TELEPHONE NUMBER: (813) 345-9371 AWARDEE NUMBER: 200-93-0680 Tuberculosis is reemerging as a health threat in the United States. Primary reasons include the susceptibility of HIV-infected persons, the lack of rapid and effective diagnostic tests, and recent outbrea ...

    SBIR Phase I 1993 Department of Health and Human Services
  10. Rapid and Sensitive Detection of Tuberculosis by MS/MS in Clinical

    SBC: ANATRACE, INC.            Topic: N/A

    PRINCIPAL INVESTIGATOR: Sonesson, Anders AWARDEE ORGANIZATION: Microbial Insights, Inc. 201 Center Park Dr., Suite 1140 Knoxville, TN 37922 TELEPHONE NUMBER: (615) 966-7356 AWARDEE NUMBER: 200-93-0681 In response to the resurgent epidemic of tuberculosis which has been greatly stimulated by the large increase in immuno-compromised persons, it is imperative that rapid and accurate diagnostic tests ...

    SBIR Phase I 1993 Department of Health and Human Services
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