Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until September, 2020.

  1. DESIGN OF A PROTON THERAPY DELIVERY SYSTEM

    SBC: Acctek Associates, Inc.            Topic: N/A

    THE LONG-RANGE GOAL OF THIS PROGRAM IS THE DEVELOPMENT AND COMMERCIALIZATION OF A PROTON THERAPY DELIVERY SYSTEM THAT WILL LEAD TO A SUBSTANTIAL ADVANCEMENT OVER EXISTING METHODSOF CANCER TREATMENT WITH PROTONS. DELIVERY SYSTEM COMPONENTS WILL INCLUDE RASTER SCANNING MAGNETS, SMALL APERTURE BENDING MAGNETS, GANTRY SYSTEMS, AND PERMANENT MAGNET TRANSPORT SYSTEMS OF WIDE MOMENTUM ACCEPTANCE. SUCH EQ ...

    SBIR Phase II 1989 Department of Health and Human Services
  2. COMPOSITE, HOLLOW FIBER MEMBRANE OXYGENATION DEVICE

    SBC: ANATRACE, INC.            Topic: N/A

    THE ACCEPTANCE OF EXTRACORPOREAL OXYGENATION DEVICES BASED ON GAS TRANSFER THROUGH A MEMBRANE WILL DEPEND TO A LARGE EXTENT ON THE AVAILABILITY OF SIMPLER, EASIER TO USE, SAFER,AND LOWERCOST DEVICES. OXYGENATORS USING MICROPOROUS HOLLOWFIBERS HAVE COME INTO WIDER USE THE LAST FIVE YEARS. THEY PRESENT MORE MEMBRANE SURFACE TO BLOOD AND GAS PHASES FOR EQUIVALENT VOLUME AND DO NOT REQUIRE A SUPPLEMEN ...

    SBIR Phase II 1989 Department of Health and Human Services
  3. GLYCATED HEMOGLOBIN BY AUTOMATED AFFINITY CHROMATOGRAPHY

    SBC: ANATRACE, INC.            Topic: N/A

    CLASSICAL ASSAYS FOR DETERMINING BLOOD AND URINE GLUCOSE HAVE LIMITED VALUE FOR THE MONITORING OF AN INDIVIDUAL'S BLOOD GLUCOSE LEVEL OVER TIME. MEASUREMENT OF GLYCATED HEMOGLOBIN (GHB) IS ALREADY GAINING ACCEPTANCE FOR MANAGEMENT OF PERSONS WITH DIABETES MELLITUS. GHB LEVELS ARE NOT ONLY USEFUL FOR DIAGNOSIS BUT ALSO FOR THE ESTABLISHMENT OF CARE GOALS AND FOR CARE REINFORCEMENT. IN THE FUTURE, M ...

    SBIR Phase II 1989 Department of Health and Human Services
  4. NEUROANATOMY WORKSTATION AND KNOWLEDGE ENGINEERING

    SBC: BIOGRAPHICS, INC.            Topic: N/A

    THIS PROJECT WILL EXPLORE THE DEVELOPMENT OF AN ADVANCED, LOW-COST COMPUTER SYSTEM, BASED ON A VIRTUAL-MEMORY INTEL 80386 PROCESSOR, FOR IMAGE ANALYSIS, GRAPHICAL DATA STORAGE, AND THREE-DIMENSIONAL RECONSTRUCTION THAT WILL BE USED AS A NEUROANATOMICAL WORKSTATION. THE STATION WILL INCLUDE PROVISIONS FOR DATA INPUT FROM A DIGITIZING TABLET, COMPUTER MICROSCOPY USING A LIGHT MICROSCOPE WITH STEPPER ...

    SBIR Phase II 1989 Department of Health and Human Services
  5. DIGITAL THERAPIST

    SBC: Digital Therapeutics Inc.            Topic: N/A

    THIS PROJECT IS DESIGNED TO DEVELOP A DEVICE, THE DIGITAL THERAPIST, THAT MAY IMPROVE EXISTING ASSESSMENTS OF EMOTIONS, PROCESSES OF PSYCHOLOGICAL CHANGE, COGNITIONS, ANDAND SITUATIONS AFFECTING BEHAVIOR IN EVERYDAY LIVING. THIS DEVICE COULD ALSO HELP CLIENTS MAKE CHANGES IN HEALTH- RELATED AND OTHER BEHAVIORS BY TEACHING THEM HOW TO BE AWAREOF THEMSELVES IN A MAXIMALLY ADAPTIVE FASHION. DURING PH ...

    SBIR Phase II 1989 Department of Health and Human Services
  6. INITIATION-PROMOTION BIOASSAY IN MOUSE LIVER

    SBC: Environmental Health Research            Topic: N/A

    SHORT-TERM/LIMITED BIOASSAYS FOR THE DETECTION OF CHEMICAL CARCINOGENS, TUMOR INITIATORS, AND TUMOR PROMOTERS HAVE BEEN RECOGNIZED AS IMPORTANT COMPONENTS TO THE DETERMINATIONOF THE CARCINOGENIC HAZARD OF ENVIRONMENTAL CHEMICALS AND COMPLEX MIXTURES. THESE BIOASSAYS ARE USEFUL TO DETERMINE (1) WHEATER A SUBSTANCE IS CARCINOGENIC, (2) DOSE-RESPONSE RELATIONSHIPS, AND (3) MECHANISM, I.E., TUMOR INIT ...

    SBIR Phase II 1989 Department of Health and Human Services
  7. POLYPORUS UMBELLATUS: A NEW BIOLOGICAL RESPONSE MODIFIER

    SBC: Hipple Cancer Research            Topic: N/A

    THE PHARMACOLOGICAL ACTIVITIES OF AN EXTRACT OF POLYPORUS UMBELLATUS, A MUSHROOM INDIGENOUS TO CHINA, HAVE BEEN INVESTIGATED EXTENSIVELY BY THE STATE PHARMACEUTICAL ADMINISTRATION OF CHINA. COMPOUND 757, A POLYSACCHARIDE PURIFIED FROM THE EXTRACT, HAS BEEN SHOWN TO HAVE ANTITUMOR AND IMMUNOMODULATORY ACTIVITIES AND ALREADY IS IN CLINICAL TRIALS WITHIN CHINA. IT HAS NEVER BEEN USED OUTSIDE OF CHINA ...

    SBIR Phase II 1989 Department of Health and Human Services
  8. TAPERED LINEAR PHASED ARRAY FOR ULTRASOUND HYPERTHERMIA

    SBC: Labthermics Technologies, Inc.            Topic: N/A

    THE OVERALL GOAL OF THIS PROJECT IS TO COMPLETE DEVELOPMENT AND TO TEST A NOVEL ULTRASONIC TAPERED LINEAR PHASED ARRAY APPLICATOR FOR HYPERTHERMIA TREATMENT. SUCH AN APPLICATOR WILL ALLOW ELECTRONIC STEERING OF THE FOCUS ALONG A DESIRED PATH WITHOUT THE USE OF A MECHANICAL SCANNING SYSTEM; IT WILL ALSO REMAIN FIXED RELATIVE TO THE PATIENT, MAKING COUPLING EASIER. THE APPLICATOR WILL BE COMPUTER CO ...

    SBIR Phase II 1989 Department of Health and Human Services
  9. GENE*DETEQ: MOLECULAR SCREENING AND ANALYSIS OF MUTATIONAL RISK

    SBC: Laboratorytories For Geneti            Topic: N/A

    A LONG-TERM OBJECTIVE OF THE SOUTHWEST FOUNDATION FOR BIOMEDICAL RESEARCH IS TO PROVIDE SERVICES FOR DETECTION ANDPREVENTION OF MUTATION IN HUMANS RESULTING IN GENETIC DISEASE AND CANCER. IT IS EXTENDING ITS SERVICES FROM IDENTIFICATION OF CHROMOSOMAL ABERRATIONS IN PATIENTS TO MOLECULAR SCREENING AND CHARACTERIZATION OF MAMMALIAN GENE MUTATIONS. SPECIFICALLY, IN PHASE I IT IS PROPOSED TO DEVELOP ...

    SBIR Phase II 1989 Department of Health and Human Services
  10. DEVELOPMENT OF INTERACTIVE RADIOGRAPHIC DISPLAY SYSTEM

    SBC: Laboratorytory Automation,            Topic: N/A

    THE PROPOSED RESEARCH SEEKS TO DEVELOP AND EVALUATE A DISPLAY STATION SUITABLE FOR ROUTINE CLINICAL USE IN MEDICALDIAGNOSTIC IMAGING. A DIGITAL DISPLAY THAT CAN BE SOLD AS ACOMPONENT OF PICTURE ARCHIVING AND COMMUNICATIONS SYSTEM WILL BE DEVELOPED. THE INVESTIGATORS INTEND TO OVERCOME THESPATIAL RESOLUTION LIMITATIONS OF EXISTING DISPLAY TECHNOLOGY BY IMPLEMENTING HIGH SPEED ZOOM AND ROAM CAPABILI ...

    SBIR Phase II 1989 Department of Health and Human Services
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