Award Data

THE LONG-RANGE GOAL OF THIS PROGRAM IS THE DEVELOPMENT AND COMMERCIALIZATION OF A PROTON THERAPY DELIVERY SYSTEM THAT WILL LEAD TO A SUBSTANTIAL ADVANCEMENT OVER EXISTING METHODSOF CANCER TREATMENT WITH PROTONS. DELIVERY SYSTEM COMPONENTS WILL INCLUDE RASTER SCANNING MAGNETS, SMALL APERTURE BENDING MAGNETS, GANTRY SYSTEMS, AND PERMANENT MAGNET TRANSPORT SYSTEMS OF WIDE MOMENTUM ACCEPTANCE. SUCH EQ ...

THIS PROJECT WILL DEVELOP AND TEST THE PROTOTYPE OF A NEW INSTRUMENT FOR MEASURING HORIZONTAL, VERTICAL, AND TORSIONAL EYE POSITIONS NONINVASIVELY, UNOBTRUSIVELY, AND SIMULTANEOUSLY. TESTING WILL BE DONE BY MEASURING A SIMULATED EYE AND BY COMPARING MEASUREMENTS ON HUMANS WITH THOSE MADE BY OTHER INSTRUMENTS. THE PROTOTYPE WILL HAVE A DIRECTIONAL RESOLUTION OF BETTER THAN 2 ARC MINUTES OVER +45 DE ...

THE ACCEPTANCE OF EXTRACORPOREAL OXYGENATION DEVICES BASED ON GAS TRANSFER THROUGH A MEMBRANE WILL DEPEND TO A LARGE EXTENT ON THE AVAILABILITY OF SIMPLER, EASIER TO USE, SAFER,AND LOWERCOST DEVICES. OXYGENATORS USING MICROPOROUS HOLLOWFIBERS HAVE COME INTO WIDER USE THE LAST FIVE YEARS. THEY PRESENT MORE MEMBRANE SURFACE TO BLOOD AND GAS PHASES FOR EQUIVALENT VOLUME AND DO NOT REQUIRE A SUPPLEMEN ...

CLASSICAL ASSAYS FOR DETERMINING BLOOD AND URINE GLUCOSE HAVE LIMITED VALUE FOR THE MONITORING OF AN INDIVIDUAL'S BLOOD GLUCOSE LEVEL OVER TIME. MEASUREMENT OF GLYCATED HEMOGLOBIN (GHB) IS ALREADY GAINING ACCEPTANCE FOR MANAGEMENT OF PERSONS WITH DIABETES MELLITUS. GHB LEVELS ARE NOT ONLY USEFUL FOR DIAGNOSIS BUT ALSO FOR THE ESTABLISHMENT OF CARE GOALS AND FOR CARE REINFORCEMENT. IN THE FUTURE, M ...

APPLIED GENETICS LABORATORIES, INC. PROPOSES TO UTILIZE NEWLY DEVELOPED MOLECULAR GENETIC TECHNIQUES TO ANALYZE THE SPECTRUM OF MUTAGENIC EVENTS THAT OCCUR AT THE TK AND HPRT LOCI IN MOUSE L5178Y CELLS. THE PURPOSE OF THESE STUDIES ISTO DETERMINE IF THE SPECTRUM OF GENETIC ABNORMALITIES REGISTERED AT THESE LOCI IS A FUNCTION OF THE HETEROZYGOUS/HOMOZYGOUS NATURE OF THE GENE LOCI INVOLVED, AND TO C ...

THIS PROGRAM IS RELATED TO THE DEVELOPMENT OF A PLATINUM-POLYSTYRENE ELECTRODE WITH TEXTURED SURFACE FOR A SUBCUTANEOUS ELECTROCATALYTIC SENSOR. THE SUBCUTANEOUS SENSOR HAS LOWER RISKS COMPARED TO AN INTRAVENOUS SENSOR, SOIT IS CONSIDERED FOR LONG-TERM MONITORING PURPOSES. IT HAS BEEN DEMONSTRATED THAT TEXTURED SURFACES ARE FAVORABLE FOR IMPLANTATION TO THE SOFT TISSUE DUE TO BETTER VASCULARIZATIO ...

CONCERN ABOUT THE EFFECTS OF HEARING IMPAIRMENT ON A CHILD'S DEVELOPMENT IS CAUSING HEARING EVALUATION TO BECOME A ROUTINE PART OF PEDIATRIC CARE. WHILE THE COMMERCIAL MARKET HAS FOCUSED ON THE IMPROVEMENT OF ELECTROPHYSIOLOGIC PROCEDURES AND EQUIPMENT, BEHAVIORAL PROCEDURES WHICH MAY BE MORE APPROPRIATELY USED WITH OLDER INFANTS AND CHILDREN HAVE BEEN LARGELY IGNORED. THE OVERALL GOAL OF THIS PRO ...

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